10 Best sinusitis nasal sprays of 2025

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1

HealthA2Z
HealthA2Z® Fluticasone Propionate Nasal Sprays | Allery Relief Spray | Runny Nose | Nasal Congestion | Sneezing | Itchy Watery Eyes | 24 Hour Allergy Relief | (2 Packs)
Main highlights

24-Hour Allergy Relief
Provides non-drowsy relief from hay fever and allergy symptoms for 24 hours.

Ideal for Moderate Allergy Sufferers
Perfect for those needing affordable, effective relief from moderate allergy symptoms.

Affordable Alternative to Name Brands
Praised for being as effective as pricier name brand options.
9.8

Exceptional

Our Rating
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Value for Money

2

NORTH AMERICAN HERB & SPICE
NORTH AMERICAN HERB & SPICE SinuOrega - 2 fl. oz. - All-Natural Nasal Spray - Oregano Oil & Sage to Support Healthy Sinus Response - Non-GMO, Alcohol Free, No Chemical or Synthetic Additives

19% Off
Main highlights

Potent Natural Ingredients
Natural Nasal Wash SinuOrega is powered by potent spice extracts and pure sea salt in a spring water base. Free of chemicals, pesticides & additives.

Effective for Sinus Relief
Ideal for sinus, bronchial, and post-nasal drip response. Recommended for use with OregaResp capsules for optimal results. Non-addictive and safe for daily use.

Immediate Sinus Relief
Customers praise the product for providing immediate relief from sinus congestion and infections, despite an initial burning sensation. Effective for allergy and sinusitis sufferers.
9.7

Exceptional

Our Rating

9.9
Gentle

9.9
quality of ingredients

9.3
Aroma
3

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.5

Excellent

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
4

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
9.4

Excellent

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
5

Arm & Hammer

Arm & Hammer Simply Saline Daily Care Nasal Mist 4.4oz, Saline Nasal Spray, Drug-Free, 2-Pack
9.1

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- usage instructions:N/A
9.0

Excellent

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
7

Beekeeper's Naturals
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
Main highlights

Natural Ingredients and Benefits
Formulated with sea salt, propolis, and xylitol for sinus relief.

Ideal for Sinus Congestion
Perfect for relieving congestion caused by pollutants and allergens.

Customer Praised Natural Formula
Highly rated for its natural, chemical-free composition.
Key specs
- effects:Decongestant, reduces swelling
- safety:Non-GMO, non-addictive
- usage:Shake well, spray twice
- formulation:Saline solution, sea salt
- dimensions:1.37 x 1.37 x 5 inches
8.8

Very Good

Our Rating
8

Mucinex
Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce
Main highlights

Fast Acting Relief
Mucinex Sinus-Max provides quick relief from nasal and sinus congestion.

Ideal for Allergies
Perfect for allergy season, offering targeted congestion relief.

Customer Praised Effectiveness
Users love its fast action and long-lasting congestion relief.
8.6

Very Good

Our Rating
9

Afrin
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
Main highlights

12 Hour Relief and Moisture
Afrin No Drip Extra Moisturizing provides up to 12 hours of congestion relief while soothing dry nasal passages.

Ideal for Nighttime and Travel
Perfect for nighttime congestion relief and reducing in-flight discomfort from sinus pressure.

Instant and Effective Congestion Relief
Praised for its fast-acting relief of nasal and sinus congestion, especially during sleep and travel.
Key specs
- features:No drip, 12 hours relief
- product dimensions:1.88 x 1.25 x 4.5 inches
- decongestant:Nasal decongestant pump mist
- active ingredients:N/A
- usage instructions:Spray two or three times
8.4

Good

Our Rating

9.9
sweat control

9.3
pain management

8.7
Simple to use
10

Nasacort
Nasacort 24HR Allergy Nasal Spray for Adults, Non-drowsy & Alcohol Free, 240 Sprays, 0.57 fl.oz. 2Ct

45% Off
Main highlights

24-Hour Relief
Nasacort provides a full 24 hours of relief from nasal allergy symptoms.

Ideal for Daily Use
Perfect for adults needing non-drowsy, long-lasting allergy relief.

Ease of Use
Praised for its easy application and effectiveness by users.
8.2

Good

Our Rating

8.7
Flavor

8.4
Simple to use

8.0
worth the money

10 Best sinusitis nasal sprays of 2025

1

HealthA2Z® Fluticasone Propionate Nasal Sprays | Allery Relief Spray | Runny Nose | Nasal Congestion | Sneezing | Itchy Watery Eyes | 24 Hour Allergy Relief | (2 Packs)

How do we rank?

How do we rank?

Analyzing top stores

2

NORTH AMERICAN HERB & SPICE SinuOrega - 2 fl. oz. - All-Natural Nasal Spray - Oregano Oil & Sage to Support Healthy Sinus Response - Non-GMO, Alcohol Free, No Chemical or Synthetic Additives

9.9

9.9

9.3

3

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

4

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

5

Arm & Hammer Simply Saline Daily Care Nasal Mist 4.4oz, Saline Nasal Spray, Drug-Free, 2-Pack

6

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

7

Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

8

Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce

9

Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL

9.9

9.3

8.7

10

Nasacort 24HR Allergy Nasal Spray for Adults, Non-drowsy & Alcohol Free, 240 Sprays, 0.57 fl.oz. 2Ct

8.7

8.4

8.0

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