Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best over counter medications of 2026
Save up to 49% off
- Home
- Health & Household
- Products
- Health care
- Over-the-counter medication
- Pain relievers
- Non-aspirin
- Acetaminophen
- Best Choice
1
TylenolTylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine
25% OffMain highlights-
100-count Tylenol Extra Strength Rapid Release Gels work quickly to relieve pain and reduce fever with 500 mg acetaminophen.
Fast Acting Relief
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Suitable for adults and children 12 years and older, making it versatile for family use.
Ideal for Adults and Teens
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Customers appreciate the fast action and effectiveness, noting the rapid relief and long-lasting results.
Highly Praised Effectiveness
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- Value for Money
2
TylenolTylenol Extra Strength Acetaminophen Rapid Release Gels, Pain Reliever & Fever Reducer, Gelcaps with Laser-Drilled Holes for Fast Release, Gentle on Stomach, 500 mg Per Gelcap, 100 Count OTC Medicine
29% OffMain highlights-
100-count Tylenol Extra Strength Rapid Release Gels work quickly to relieve pain and reduce fever with 500 mg acetaminophen.
Fast Acting Relief
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Suitable for adults and children 12 years and older, making it versatile for family use.
Ideal for Adults and Teens
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Customers appreciate the fast action and effectiveness, noting the rapid relief and long-lasting results.
Highly Praised Effectiveness
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3
ImodiumImodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow
46% OffMain highlights-
Imodium A-D Softgels provide fast, effective relief for diarrhea symptoms, restoring natural rhythm in one dose.
Effective Relief
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Perfect for acute, active, and travelers diarrhea, suitable for ages 12 and up.
Ideal for Travel
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Customers praise its quick action and effectiveness in relieving stomach issues.
Customer Satisfaction
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4
ImodiumImodium A-D Fast-Acting Anti-Diarrheal Softgels, Loperamide HCl 2 mg, Travel Essential Diarrhea Relief Medicine for Adults, 24 Count, Anti Diarrhea Pills, Ages 12+, Easy to Swallow
49% OffMain highlights-
Imodium A-D Softgels provide fast, effective relief for diarrhea symptoms, restoring natural rhythm in one dose.
Effective Relief
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Perfect for acute, active, and travelers diarrhea, suitable for ages 12 and up.
Ideal for Travel
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Customers praise its quick action and effectiveness in relieving stomach issues.
Customer Satisfaction
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5
Amazon Basic CareAmazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)
Main highlights-
Contains 200 mg ibuprofen for effective pain and fever relief.
Pain Relief and Fever Reduction
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Perfect for muscular aches, arthritis, toothache, backache, and more.
Ideal for Various Aches
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Praised for affordability and convenience of Amazon delivery.
Best Price and Convenience
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6
Amazon Basic CareAmazon Basic Care Ibuprofen Tablets 200 mg, Pain Reliever/Fever Reducer, Body Aches, Headache, Arthritis Pain Relief and More, 500 Count (Packaging may vary)
Main highlights-
Contains 200 mg ibuprofen for effective pain and fever relief.
Pain Relief and Fever Reduction
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Perfect for muscular aches, arthritis, toothache, backache, and more.
Ideal for Various Aches
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Praised for affordability and convenience of Amazon delivery.
Best Price and Convenience
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7
TUMSTUMS Chewy Bites Chewable Antacid Tablets with Gas Relief, Lemon & Strawberry - 54 Count
Main highlights-
54 TUMS Chewy Bites provide quick relief from heartburn, sour stomach, acid indigestion, and gas with tasty lemon and strawberry flavors.
Fast and Powerful Relief
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Perfect for those experiencing heartburn, sour stomach, acid indigestion, and gas, especially after consuming gassy foods like beans and broccoli.
Ideal for Quick Heartburn Relief
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Customers love the delicious lemon and strawberry flavors and the chewy texture, making them a preferred choice over other antacid options.
Highly Praised Taste and Texture
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8
TUMSTUMS Chewy Bites Chewable Antacid Tablets with Gas Relief, Lemon & Strawberry - 54 Count
Main highlights-
54 TUMS Chewy Bites provide quick relief from heartburn, sour stomach, acid indigestion, and gas with tasty lemon and strawberry flavors.
Fast and Powerful Relief
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Perfect for those experiencing heartburn, sour stomach, acid indigestion, and gas, especially after consuming gassy foods like beans and broccoli.
Ideal for Quick Heartburn Relief
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Customers love the delicious lemon and strawberry flavors and the chewy texture, making them a preferred choice over other antacid options.
Highly Praised Taste and Texture
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9
LudensLuden's Sore Throat Relief Lozenges for Minor Everyday Irritation & Dry Mouth, Wild Cherry Flavored Drops, 30 Count
Main highlights-
Ludens Wild Cherry throat drops use 2.8 mg of pectin for a soothing throat coat without menthol.
Soothing Relief Without Medicated Ingredients
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Designed for easy use anywhere, these drops relieve minor throat irritation anytime.
Perfect for On-the-Go Minor Throat Irritation
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Customers praise the great-tasting wild cherry flavor, a nostalgic favorite.
Delicious Wild Cherry Flavor
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10
LudensLuden's Sore Throat Relief Lozenges for Minor Everyday Irritation & Dry Mouth, Wild Cherry Flavored Drops, 30 Count
Main highlights-
Ludens Wild Cherry throat drops use 2.8 mg of pectin for a soothing throat coat without menthol.
Soothing Relief Without Medicated Ingredients
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Designed for easy use anywhere, these drops relieve minor throat irritation anytime.
Perfect for On-the-Go Minor Throat Irritation
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Customers praise the great-tasting wild cherry flavor, a nostalgic favorite.
Delicious Wild Cherry Flavor
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