10 Best excedrin pm sleep aids of 2026

Save up to 31% off

1

Tylenol

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150 ct

27% Off
9.8

Exceptional

Our Rating

9.7
pain management

9.5
worth the money

9.3
quality of sleep
How do we rank?

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Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
2

Tylenol

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150 ct

31% Off
9.7

Exceptional

Our Rating

9.7
pain management

9.5
worth the money

9.3
quality of sleep
3

Excedrin
Excedrin PM for Headache Relief, Acetaminophen 250mg, Aspirin 250mg, Diphenhydramine Citrate 38mg, Pain Reliever, Nighttime Sleep-Aid, 100 Count
Main highlights

Triple Action Relief
Combines aspirin, acetaminophen, and diphenhydramine for effective pain relief and sleep aid.

Ideal for Nighttime Use
Perfect for those with headaches and sleeplessness, offering relief without caffeine.

Highly Praised Sleep Aid
Customers appreciate its ability to provide restful sleep during migraines.
Key specs
- form:Caplet
- active ingredient:Diphenhydramine, aspirin, acetaminophen
- pain relief:Headache and muscle pain
- flavor:N/A
- dosing instructions:N/A
9.4

Excellent

Our Rating

9.5
worth the money

9.5
pain management
4

Excedrin
Excedrin PM for Headache Relief, Acetaminophen 250mg, Aspirin 250mg, Diphenhydramine Citrate 38mg, Pain Reliever, Nighttime Sleep-Aid, 100 Count
Main highlights

Triple Action Relief
Combines aspirin, acetaminophen, and diphenhydramine for effective pain relief and sleep aid.

Ideal for Nighttime Use
Perfect for those with headaches and sleeplessness, offering relief without caffeine.

Highly Praised Sleep Aid
Customers appreciate its ability to provide restful sleep during migraines.
Key specs
- form:Caplet
- active ingredient:Diphenhydramine, aspirin, acetaminophen
- pain relief:Headache and muscle pain
- flavor:N/A
- dosing instructions:N/A
9.1

Excellent

Our Rating

9.5
worth the money

9.5
pain management
5

HealthA2Z
HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))
Main highlights

Fast Acting Pain Relief and Sleep Aid
500 mg Acetaminophen and 25 mg Diphenhydramine provide quick pain relief and help you fall asleep.

Ideal for Nighttime Use
Perfect for adults needing pain relief and better sleep at night.

Value for Money
Customers appreciate the cost-effectiveness without compromising quality.
9.0

Excellent

Our Rating
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6

HealthA2Z
HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

10% Off
Main highlights

Fast Acting Pain Relief and Sleep Aid
500 mg Acetaminophen and 25 mg Diphenhydramine provide quick pain relief and help you fall asleep.

Ideal for Nighttime Use
Perfect for adults needing pain relief and better sleep at night.

Value for Money
Customers appreciate the cost-effectiveness without compromising quality.
8.9

Very Good

Our Rating
7

Amazon Basic Care
Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may vary
Main highlights

Effective Pain Relief and Sleep Aid
Amazon Basic Care Acetaminophen PM combines 500 mg acetaminophen and 25 mg diphenhydramine HCl to relieve pain and aid sleep. Non-habit forming and gluten-free.

Ideal for Nighttime Pain and Sleep Issues
Perfect for adults and children over 12 experiencing minor pain and sleeplessness. Easy-to-swallow caplets with a child-resistant cap.

Highly Praised for Value and Effectiveness
Customers appreciate its affordability and effectiveness, comparing it favorably to name brands like Tylenol PM. Non-addictive and provides solid pain relief and sleep aid.
8.6

Very Good

Our Rating

9.5
simple to consume

9.5
worth the money

9.3
quality of sleep
8

Amazon Basic Care
Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may vary
Main highlights

Effective Pain Relief and Sleep Aid
Amazon Basic Care Acetaminophen PM combines 500 mg acetaminophen and 25 mg diphenhydramine HCl to relieve pain and aid sleep. Non-habit forming and gluten-free.

Ideal for Nighttime Pain and Sleep Issues
Perfect for adults and children over 12 experiencing minor pain and sleeplessness. Easy-to-swallow caplets with a child-resistant cap.

Highly Praised for Value and Effectiveness
Customers appreciate its affordability and effectiveness, comparing it favorably to name brands like Tylenol PM. Non-addictive and provides solid pain relief and sleep aid.
8.3

Good

Our Rating

9.5
simple to consume

9.5
worth the money

9.3
quality of sleep
9

Tylenol

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct
8.2

Good

Our Rating
10

Tylenol

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct
8.1

Good

Our Rating

10 Best excedrin pm sleep aids of 2026

1

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150 ct

9.7

9.5

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 150 ct

9.7

9.5

9.3

3

Excedrin PM for Headache Relief, Acetaminophen 250mg, Aspirin 250mg, Diphenhydramine Citrate 38mg, Pain Reliever, Nighttime Sleep-Aid, 100 Count

9.5

9.5

4

Excedrin PM for Headache Relief, Acetaminophen 250mg, Aspirin 250mg, Diphenhydramine Citrate 38mg, Pain Reliever, Nighttime Sleep-Aid, 100 Count

9.5

9.5

5

HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

6

HealthA2Z® Extra Strength Pain Relief PM| Acetaminophen 500mg | Diphenhydramine 25mg | Pain Reliever & Nighttime Sleep Aid | (365 Count (Pack of 1))

7

Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may vary

9.5

9.5

9.3

8

Amazon Basic Care Acetaminophen PM Caplets, Pain Reliever Plus Nighttime Sleep Aid, Extra Strength, Helps Occasional Minor Aches, Pains and Headache Relief, 100 Count, Packaging may vary

9.5

9.5

9.3

9

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct

10

Tylenol PM Extra Strength Nighttime Pain Reliever & Sleep Aid Caplets, 500 mg Acetaminophen & 25 mg Diphenhydramine HCl, Relief for Nighttime Aches & Pains, Non-Habit Forming, 100 ct

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