October 26, 2025

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10 Best decongestant nasal sprays of 2025

Save up to 32% off

Best Choice

1

Vicks
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2
Main highlights

Instant Sinus Relief
Clears stuffy nose in seconds, works 6x faster than tablets.

Ideal for Cold and Allergy
Effective for congestion and sinus pressure relief day or night.

Praised Metered Mist
Fine mist prevents dripping, ensuring easy and mess-free use.
Key specs
- features:Instant sinus relief
- product dimensions:5.08 x 2.76 x 2.13 inches
- decongestant:Nasal Spray
- active ingredients:N/A
- usage instructions:N/A
9.9

Exceptional

Our Rating
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Value for Money

2

Afrin
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
Main highlights

Maximum Strength Relief
Afrin No Drip provides instant, long-lasting relief for severe nasal congestion.

Ideal for Allergy Season
Perfect for allergy sufferers needing effective nasal congestion relief.

Long-Lasting Effect
Customers praise its 12-hour effectiveness and non-drip formulation.
9.8

Exceptional

Our Rating

9.5
Simple to use

9.1
worth the money

8.9
Moisturizing
3

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

29% Off
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- usage instructions:N/A
9.7

Exceptional

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
4

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.5

Excellent

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
5

Amazon Basic Care
Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)
Main highlights

Maximum Strength Relief
Provides 12-hour relief from nasal congestion due to colds and allergies.

Ideal for Cold and Allergy Sufferers
Perfect for those needing fast, effective nasal decongestion.

Praised for Value and Performance
Customers appreciate the effective relief and cost savings over name brands.
Key specs
- features:12-hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- decongestant:Yes
- active ingredients:Oxymetazoline HCl
- usage instructions:N/A
9.4

Excellent

Our Rating

9.1
worth the money

8.2
Comfort

8.0
Flavor
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6

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
9.3

Excellent

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
7

Amazon Basic Care
Amazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides maximum strength nasal congestion relief for 12 hours.

Best for Cold and Allergy Relief
Ideal for relieving nasal congestion from colds and allergies.

Customer Praise for Effectiveness
Praised for opening nasal passages quickly and effectively.
Key specs
- features:12 hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- decongestant:Yes
- active ingredients:Oxymetazoline HCl
- usage instructions:N/A
9.2

Excellent

Our Rating

8.9
Simple to use

8.7
worth the money

8.2
Flavor
8

Afrin
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
Main highlights

12 Hour Relief and Moisture
Afrin No Drip Extra Moisturizing provides up to 12 hours of congestion relief while soothing dry nasal passages.

Ideal for Nighttime and Travel
Perfect for nighttime congestion relief and reducing in-flight discomfort from sinus pressure.

Instant and Effective Congestion Relief
Praised for its fast-acting relief of nasal and sinus congestion, especially during sleep and travel.
Key specs
- features:No drip, 12 hours relief
- product dimensions:1.88 x 1.25 x 4.5 inches
- decongestant:Nasal decongestant pump mist
- active ingredients:N/A
- usage instructions:Spray two or three times
9.0

Excellent

Our Rating

9.9
sweat control

9.3
pain management

8.7
Simple to use
9

MAJOR

MAJOR 12-Hour Nasal Decongestant Spray-Oxymetazoline Hydrochloride 0.05% Nose Spray for Adults and Kids - Soothing Pump Mist for Cold, Allergy, Nasal Congestion, and Sinus Relief - 1 Fl. Oz.(3 Pack)
8.9

Very Good

Our Rating
10

Amazon Basic Care
Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)

32% Off
Main highlights

Key Features
Fast-acting phenylephrine HCl for up to four hours of nasal congestion relief, non-drowsy formula, suitable for ages 12 and older.

Ideal Use Cases
Effective for relieving nasal and sinus congestion, swollen nasal membranes, and sinus pressure, ideal for daytime use.

Customer Praise
Users highly appreciate its fast relief for nasal congestion, highlighting its effectiveness and the convenience of a non-drowsy formula.
Key specs
- features:Fast-acting, non-drowsy
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Phenylephrine hydrochloride
- active ingredients:Phenylephrine hydrochloride 1%
- usage instructions:For ages 12 years and older
8.8

Very Good

Our Rating

8.2
Long life

8.0
worth the money

8.0
Comfort

10 Best decongestant nasal sprays of 2025

1

Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

How do we rank?

How do we rank?

Analyzing top stores

2

Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

9.5

9.1

8.9

3

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

4

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

5

Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)

9.1

8.2

8.0

6

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

7

Amazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 fl oz (Pack of 1)

8.9

8.7

8.2

8

Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL

9.9

9.3

8.7

9

MAJOR 12-Hour Nasal Decongestant Spray-Oxymetazoline Hydrochloride 0.05% Nose Spray for Adults and Kids - Soothing Pump Mist for Cold, Allergy, Nasal Congestion, and Sinus Relief - 1 Fl. Oz.(3 Pack)

10

Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)

8.2

8.0

8.0

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