10 Best decongestants of 2025

Save up to 26% off

Best Choice

1

GenCare
GenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness

25% Off
Main highlights

Maximum Strength Relief
10 mg Phenylephrine HCl provides strong sinus and nasal congestion relief.

Ideal for Chronic Congestion
Perfect for families or individuals with frequent allergy symptoms.

Highly Praised Value
Customers appreciate the affordability and effectiveness compared to other brands.
9.8

Exceptional

Our Rating

9.7
worth the money

9.5
dispense easily

9.3
simple to consume
How do we rank?

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Value for Money

2

Vicks
Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.6

Exceptional

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
3

HealthA2Z
HealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Maximum Strength | Non-Drowsy Nasal & Sinus Congestion Relief Due to Cold & Allergies (90 Count (Pack of 1))
Main highlights

Non-Drowsy Relief
Provides non-drowsy relief for nasal and sinus congestion.

Ideal for Cold and Allergies
Perfect for temporary relief of sinus congestion and pressure.

Highly Effective
Praised by users for excellent congestion relief performance.
9.5

Excellent

Our Rating

9.9
worth the money

9.7
pain management

9.3
quality of ingredients
4

Sudafed
Sudafed PE Sinus Congestion Relief Tablets, Maximum Strength, Non-Drowsy 10 mg Phenylephrine HCI Decongestant for Sinus Pressure & Nasal Congestion Relief from colds or Allergies, 18 ct
Main highlights

Key Features
Max strength phenylephrine HCl for non-drowsy sinus and nasal congestion relief, reduces swelling for easier breathing, fast-acting formula.

Ideal Use Cases
Best for relieving sinus pressure and congestion from colds, hay fever, or allergies, suitable for adults and children 12 and older.

Customer Praise
Highly praised for its quick relief of severe sinus pressure and congestion, becoming a go-to for sufferers of common cold and allergies.
9.3

Excellent

Our Rating

9.1
simple to consume

8.4
worth the money

8.4
Comfort
5

P Puregen Labs
Puregen Labs Nasal Decongestant PE 100 Tablets | Phenylephrine HCl 10 mg Tablets | Maximum Strength | Non Drowsy Nasal & Sinus Congestion Relief Due to Cold or Allergies (1)
Main highlights

Maximum Strength Non-Drowsy Relief
Provides maximum strength, non-drowsy relief for nasal and sinus congestion due to cold or allergies.

Ideal for Busy Schedules
Perfect for use when you can't miss work, school, or important events.

Highly Rated for Fast Shipping
Customers frequently praise the product for its fast shipping and effective decongestion.
9.2

Excellent

Our Rating

9.9
simple to consume

9.7
worth the money

9.3
quality of ingredients
See Today’s Deals & Prices
6

Mucinex
Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

21% Off
Main highlights

Maximum Strength Relief
Provides relief from pain, headache, nasal, sinus, and chest congestion.

Ideal for Severe Congestion
Best for adults experiencing severe sinus and nasal congestion.

Praised for Effectiveness
Customers appreciate the product's good results despite small packaging.
9.1

Excellent

Our Rating
7

Sudafed
Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

20% Off
Main highlights

Comprehensive Relief
Provides non-drowsy relief from sinus pain, pressure, and congestion with acetaminophen, phenylephrine HCl, and guaifenesin.

Ideal for Cold and Allergy Symptoms
Perfect for alleviating symptoms of hay fever, upper respiratory allergies, and the common cold.

Highly Effective for Stuffy Nose
Praised for its effectiveness in relieving stuffy noses, according to customer reviews.
9.0

Excellent

Our Rating

9.9
simple to consume

9.7
pain management

8.0
For Gentle skin
8

Sudafed
Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct

26% Off
Main highlights

Powerful Sinus Relief
20-count of maximum strength tablets for day and night sinus congestion relief.

Best for All-Day Use
Ideal for relieving sinus pressure and congestion both day and night.

Fast Symptom Relief
Customers praise quick relief from sinus congestion and pressure.
8.9

Very Good

Our Rating

9.5
simple to consume

8.7
worth the money

8.4
pain management
9

NUVICARE
NUVICARE Max Strength PE Phenylephrine HCl 10mg Non Drowsy Nasal Decongestant - Allergy Sinus Congestion Relief Compare to Sudafed PE Decongestant Tablets - Sinus Decongestants for Adults (100 Count)
Main highlights

Powerful Nasal Decongestion
Contains phenylephrine HCl 10mg for direct nasal congestion relief.

Ideal for Daytime Use
Non-drowsy formula allows for all-day relief without drowsiness.

Highly Recommended by Users
Praised for effectiveness and ease of use compared to brands.
8.8

Very Good

Our Rating
10

HealthA2Z
HealthA2Z® Decongestant PE | Phenylephrine HCl 5 mg | Non-Drowsy Nasal & Sinus Congestion Relief Due to Cold & Allergies (300 Count, 5mg)
Main highlights

Affordable Large Quantity
300 count bottle offers cost-effective decongestant solution.

Ideal for Allergy Relief
Perfect for year-round allergy sufferers needing frequent relief.

Praised for Affordability
Customers appreciate the value and effectiveness of this product.
8.7

Very Good

Our Rating

10 Best decongestants of 2025

1

GenCare - Nasal Decongestant (10mg Tablets) Phenylephrine HCl (300 Tablets Per Bottle) | Value Pack Non Drowsy Sinus and Nasal Congestion Relief | Lower Sinus Pressure Due to Allergies or Illness

9.7

9.5

9.3

2

Vicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

3

HealthA2Z® Decongestant PE | Phenylephrine HCl 10 mg | Maximum Strength | Non-Drowsy Nasal & Sinus Congestion Relief Due to Cold & Allergies (90 Count (Pack of 1))

9.9

9.7

9.3

4

Sudafed PE Sinus Congestion Relief Tablets, Maximum Strength, Non-Drowsy 10 mg Phenylephrine HCI Decongestant for Sinus Pressure & Nasal Congestion Relief from colds or Allergies, 18 ct

9.1

8.4

8.4

5

Puregen Labs Nasal Decongestant PE 100 Tablets | Phenylephrine HCl 10 mg Tablets | Maximum Strength | Non Drowsy Nasal & Sinus Congestion Relief Due to Cold or Allergies (1)

9.9

9.7

9.3

6

Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

7

Sudafed PE Head Congestion + Mucus Tablets for Sinus Pressure, Pain & Congestion, 24 ct

9.9

9.7

8.0

8

Sudafed PE Sinus Congestion Day + Night Maximum Strength Decongestant & Antihistamine Tablets with Phenylephrine HCl & Diphenhydramine HCl, Helps Nasal & Sinus Pressure & Congestion, 20 ct

9.5

8.7

8.4

9

NUVICARE Max Strength PE Phenylephrine HCl 10mg Non Drowsy Nasal Decongestant - Allergy Sinus Congestion Relief Compare to Sudafed PE Decongestant Tablets - Sinus Decongestants for Adults (100 Count)

10

HealthA2Z® Decongestant PE | Phenylephrine HCl 5 mg | Non-Drowsy Nasal & Sinus Congestion Relief Due to Cold & Allergies (300 Count, 5mg)

Sign up and get exclusive special deals