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10 Best oxymetazoline nasal sprays of 2026
Explore top picks
Best Choice1
9.8Exceptional
MAJOR Maximum Strength Nasal Decongestant Spray, Oxymetazoline HCl 0.05% Pump Mist, Non-Drowsy Nasal Spray, up to 12-Hour Relief from Nasal Congestion, Colds, and Allergies 1 Fl. Oz. (12-Pack)
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package dimensions:12.05 x 4.96 x 2.72 inches 1.52 Pounds
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asin:B083W2KYFB
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date first available:January 14, 2020
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manufacturer:Major Pharmaceuticals
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product dimensions:N/A
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Value for Money2
9.7Exceptional
MAJOR Maximum Strength Nasal Decongestant Spray, Oxymetazoline HCl 0.05% Pump Mist, Non-Drowsy Nasal Spray, up to 12-Hour Relief from Nasal Congestion, Colds, and Allergies 1 Fl. Oz. (6-Pack)
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package dimensions:6.42 x 4.96 x 2.83 inches 11.99 ounces
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asin:B083VVHXR5
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date first available:January 15, 2020
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manufacturer:Major Pharmaceuticals
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product dimensions:N/A
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3
berkley jensen9.6Exceptional
Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fl Oz (Pack of 3)
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4
9.5Excellent
MAJOR Maximum Strength Nasal Decongestant Spray, Oxymetazoline HCl 0.05% Pump Mist, Non-Drowsy Nasal Spray, up to 12-Hour Relief from Nasal Congestion, Colds, and Allergies 1 Fl. Oz. (3-Pack)
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package dimensions:6.38 x 5.31 x 1.57 inches 6.38 ounces
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asin:B083VVK3HG
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date first available:January 15, 2020
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manufacturer:Major Pharmaceuticals Rugby Laboratories
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product dimensions:N/A
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5
ASSURED9.3Excellent
(12 pack) Nasal Relief Spray, 12 hour Pump Mist (Oxymetazoline HCL) 0.5 fl oz
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package dimensions:N/A
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asin:B006V6H4GU
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date first available:January 9, 2012
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manufacturer:Assured
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product dimensions:11.57 x 4.84 x 2.64 inches 0.5 ounces
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6
Greenbrier9.0Excellent
Assured Nasal Relief Spray, 12 Hour Pump Mist Oxymetazoline HCL, 0.5 fl. Oz (6 Pack)
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7
8.9Very Good
Afrin No Drip Extra Moisturizing Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Sinus Pressure and Dry Nasal Passages, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
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package dimensions:N/A
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asin:B08H9CKYKL
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date first available:September 1, 2020
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manufacturer:AmazonUs/BAYR7
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product dimensions:1.88 x 2.75 x 4.5 inches 1.92 ounces
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8
8.8Very Good
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
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package dimensions:N/A
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asin:B07HG5JMBR
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date first available:September 10, 2018
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manufacturer:Bayer Healthcare LLC
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product dimensions:1.88 x 2.75 x 4.5 inches; 2.4 ounces
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9
Vicks8.6Very Good
Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)
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is discontinued by manufacturer:No
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asin:B073MY31H6
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product dimensions:2.56 x 3.86 x 5.4 inches; 1 ounces
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date first available:April 10, 2017
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manufacturer:Procter & Gamble - HABA Hub
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10
ASSURED8.5Good
Nasal Relief Spray, Pump Mist, Anti-drip, Severe Congestion, (Oxymetazoline HCI) 12 Hours, 6 Pack.
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