10 Best topical pain reliefs of 2025

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Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2
Main highlights

Powerful Topical Relief
Voltaren Arthritis Pain Gel offers prescription-strength relief for arthritis, improving mobility and reducing stiffness with a non-greasy formula.

Ideal for Arthritis Pain
Perfect for hand, wrist, elbow, ankle, foot, and knee pain relief when used up to four times daily.

Doctor Recommended Effectiveness
Customers praise its effectiveness, often noting significant relief and satisfaction with results.
9.7

Exceptional

Our Rating
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Value for Money

2

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
Main highlights

Powerful Topical Relief
Voltaren Gel offers prescription-strength arthritis pain relief, reducing stiffness and improving mobility.

Ideal for Joint Pain
Best for hand, wrist, elbow, ankle, foot, or knee pain relief.

Highly Praised Easy Cap
Customers appreciate the new easy-to-open cap for convenience.
9.6

Exceptional

Our Rating

9.3
pain management

8.0
worth the money
3

Boiron
Boiron Arnicare Gel Natural Soothing Relief for Joint Pain, Muscle Pain, Inflammation, Soreness, and Bruises - Non-greasy and Fragrance-Free - 2.6 oz

33% Off
Main highlights

Natural Pain Relief and Fast Absorption
Boiron Arnicare Gel offers temporary relief for muscle pain and stiffness with a fast-absorbing, non-greasy formula.

Ideal for Post-Workout and Minor Injuries
Perfect for soothing muscle soreness and reducing bruising after intense workouts, minor injuries, or overexertion.

Highly Praised Non-Sticky Application
Customers appreciate the gel's quick absorption and non-sticky, residue-free finish.
9.5

Excellent

Our Rating

9.3
Aroma

8.9
worth the money

8.7
Long life
4

HealthWise

HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy, Unscented Formula | Topical Anesthetic
9.3

Excellent

Our Rating
5

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

34% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
Key specs
- Package Type:Bottle
- Active Ingredients:4% Lidocaine
- Application Method:Topical
- Effect Duration:Hours
- Formulation:Cream
9.0

Excellent

Our Rating

8.4
worth the money

8.4
pain management
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6

Bengay
Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ
Main highlights

Ultra-Strong Relief
Contains camphor, menthol, and methyl salicylate for effective pain relief.

Ideal for Minor Pains
Perfect for backaches, arthritis, muscle, joint pain, and bruises.

Menthol Scent Praised
Menthol scent is strong but effective for pain relief.
8.9

Very Good

Our Rating

8.4
worth the money

8.2
Aroma

8.0
pain management
7

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
8.6

Very Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients
8

Advil
Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz
Main highlights

Fast Relief Formula
Unique blend with four powerful ingredients for quick pain relief.

Ideal for Muscle and Joint Pain
Perfect for relieving muscle, joint, and back pain without a prescription.

Pleasant Minty Scent
Praised for its subtle mint fragrance that doesn't linger.
Key specs
- Package Type:Tube
- Active Ingredients:4 powerful pain fighting ingredients
- Application Method:Topical
- Effect Duration:Up to 8 hours
- Formulation:Cream
8.5

Good

Our Rating
9

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
Main highlights

Powerful Topical Pain Relief
Voltaren Gel provides prescription-strength relief for arthritis pain, improving mobility and reducing stiffness without the need for pills.

Ideal for Joint Pain Management
Best used for hand, wrist, elbow, ankle, foot, or knee pain with significant relief in seven days.

Highly Effective According to Users
Customers praise its effectiveness as a topical pain reliever, often noting its significant impact within a few uses.
Key specs
- Active Ingredients:Diclofenac Sodium
- Gel Type:Non-greasy, clean scented
- Formulation:Topical Gel
- Application Area:Hand, wrist, elbow, ankle
- Texture:Non-greasy
8.4

Good

Our Rating

8.0
pain management

8.0
worth the money
10

HealthCareAisle
HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)

29% Off
Main highlights

Effective Arthritis Relief
Clinically proven to relieve arthritis pain with Diclofenac Sodium.

Ideal for Joint Pain
Targets inflammation in hands, wrists, elbows, feet, ankles, and knees.

Cost-Effective Solution
Praised for being as effective as Voltaren at a lower price.
8.2

Good

Our Rating

9.1
worth the money

9.1
pain management

10 Best topical pain reliefs of 2025

1

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2

How do we rank?

How do we rank?

Analyzing top stores

2

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

9.3

8.0

3

Boiron Arnicare Gel Natural Soothing Relief for Joint Pain, Muscle Pain, Inflammation, Soreness, and Bruises - Non-greasy and Fragrance-Free - 2.6 oz

9.3

8.9

8.7

4

HealthWise 4% Lidocaine Roll-On | OTC Strength | Pain Relief Liquid | 2.5 oz. 73 mL | Non-Greasy, Unscented Formula | Topical Anesthetic

5

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

6

Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

8.4

8.2

8.0

7

Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

8

Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz

9

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube

8.0

8.0

10

HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)

9.1

9.1

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