10 Best topical arthritis creams of 2025

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1

Curist
Curist Diclofenac Arthritis Cream Gel 1% (3 Tubes of 150g)- Stop Pain in Wrists, Feet, Elbows, & Ankles. Hand Arthritis Pain Relief & Knee Arthritis Pain Relief (3 Pack, 5.29 oz ea.)
Main highlights

Maximum Strength Relief
Contains maximum OTC strength diclofenac for effective arthritis pain relief.

Ideal for Joint Pain
Best for wrists, feet, elbows, ankles, and knees.

Customer Satisfaction
Praised for effectiveness and affordability compared to Voltaren.
Key specs
- Active Ingredients:Diclofenac sodium
- Gel Type:Non-greasy
- Formulation:Cream gel
- Application Area:Hand, wrist, elbow, foot, ankle, knees
- Texture:Non-greasy finish
9.8

Exceptional

Our Rating
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Value for Money

2

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size Tube
Main highlights

Powerful Topical Relief
Voltaren Gel provides prescription-strength arthritis pain relief, reduces stiffness, and improves mobility.

Ideal for Multi-Joint Pain
Apply to hand, wrist, elbow, ankle, foot, or knee pain for targeted relief.

Easy Open Cap
Convenient flip cap design praised for ease of use.
9.6

Exceptional

Our Rating

8.4
Simple to use

8.0
pain management

8.0
worth the money
3

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

19% Off
Main highlights

Powerful Topical Relief
Voltaren Gel offers prescription-strength arthritis pain relief, reducing stiffness and improving mobility.

Ideal for Joint Pain
Best for hand, wrist, elbow, ankle, foot, or knee pain relief.

Highly Praised Easy Cap
Customers appreciate the new easy-to-open cap for convenience.
9.5

Excellent

Our Rating

9.3
pain management

8.0
worth the money
4

HealthCareAisle
HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)
Main highlights

Effective Arthritis Relief
Clinically proven to relieve arthritis pain with Diclofenac Sodium.

Ideal for Joint Pain
Targets inflammation in hands, wrists, elbows, feet, ankles, and knees.

Cost-Effective Solution
Praised for being as effective as Voltaren at a lower price.
9.3

Excellent

Our Rating

9.1
worth the money

9.1
pain management
5

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
Main highlights

Powerful Topical Pain Relief
Voltaren Gel provides prescription-strength relief for arthritis pain, improving mobility and reducing stiffness without the need for pills.

Ideal for Joint Pain Management
Best used for hand, wrist, elbow, ankle, foot, or knee pain with significant relief in seven days.

Highly Effective According to Users
Customers praise its effectiveness as a topical pain reliever, often noting its significant impact within a few uses.
Key specs
- Active Ingredients:Diclofenac Sodium
- Gel Type:Non-greasy, clean scented
- Formulation:Topical Gel
- Application Area:Hand, wrist, elbow, ankle
- Texture:Non-greasy
9.2

Excellent

Our Rating

8.0
pain management

8.0
worth the money
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6

Amazon Basic Care
Amazon Basic Care Arthritis Pain Relieving Gel, Diclofenac Sodium Topical Gel, 1% (NSAID), 5.29 Oz (150 Grams) (Packaging may vary)
Main highlights

Effective Arthritis Pain Relief
Contains 1% diclofenac sodium, an NSAID, for targeted arthritis pain relief.

Ideal for Multiple Body Areas
Perfect for hand, wrist, elbow, foot, ankle, and knee pain.

Highly Praised for Value
Comparable to Voltaren, praised for effectiveness at a lower price.
Key specs
- Active Ingredients:Diclofenac sodium
- Gel Type:NSAID
- Formulation:Gel
- Application Area:Hand, wrist, elbow, foot, ankle, knee
- Texture:N/A
9.1

Excellent

Our Rating

8.4
worth the money

8.4
pain management

8.0
Aroma
7

Aspercreme

Aspercreme Original Pain Relief Cream for Arthritis, Joint & Muscle Pain, Non-Greasy Topical Analgesic with Moisturizing Aloe & Max-Strength 10% Trolamine Salicylate, 3 oz.

13% Off
9.0

Excellent

Our Rating

9.7
pain management

9.5
Simple to use

9.3
dispense easily
8

Curist
Curist Diclofenac Sodium Topical Gel 1 Percent 150g for Arthritis Pain - Joint Pain Relief for Hand/Foot Pain, Knee/Elbow Pain & Ankle Pain - 1% - 5.29oz
Main highlights

Maximum Strength Relief
Penetrates deeply to relieve joint pain, stiffness, and restore mobility with continued use.

Ideal for Joint Pain
Best for arthritis pain in hands, feet, knees, elbows, and ankles.

Affordable and Effective
Praised for being as effective as expensive brands, with a fair price.
Key specs
- Active Ingredients:Diclofenac Sodium
- Gel Type:Non-greasy
- Formulation:Cream Gel
- Application Area:Hand, wrist, elbow, foot, ankle, knees
- Texture:Non-greasy finish
8.8

Very Good

Our Rating
9

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
8.5

Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients
10

Boiron
Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz

30% Off
Main highlights

Dual Action Pain Relief
Combines Arnica Montana and Devil's Claw for effective arthritis relief.

Ideal for Joint Pain
Suitable for knees, hands, wrists, elbows, and muscles.

Praised Quick Absorption
Customers love its fast absorption and non-greasy texture.
Key specs
- Active Ingredients:Arnica Montana, Harpagophytum
- Gel Type:Non-greasy
- Formulation:Topical
- Application Area:All joints
- Texture:Light, silky
8.2

Good

Our Rating

10 Best topical arthritis creams of 2025

1

Curist Diclofenac Arthritis Cream Gel 1% (3 Tubes of 150g)- Stop Pain in Wrists, Feet, Elbows, & Ankles. Hand Arthritis Pain Relief & Knee Arthritis Pain Relief (3 Pack, 5.29 oz ea.)

How do we rank?

How do we rank?

Analyzing top stores

2

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g Tube And 20 g Travel Size Tube

8.4

8.0

8.0

3

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

9.3

8.0

4

HealthCareAisle Diclofenac Gel, 1%, Arthritis Pain Relief - 150 g tube - Original Prescription Strength (NSAID)

9.1

9.1

5

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube

8.0

8.0

6

Amazon Basic Care Arthritis Pain Relieving Gel, Diclofenac Sodium Topical Gel, 1% (NSAID), 5.29 Oz (150 Grams) (Packaging may vary)

8.4

8.4

8.0

7

Aspercreme Original Pain Relief Cream for Arthritis, Joint & Muscle Pain, Non-Greasy Topical Analgesic with Moisturizing Aloe & Max-Strength 10% Trolamine Salicylate, 3 oz.

9.7

9.5

9.3

8

Curist Diclofenac Sodium Topical Gel 1 Percent 150g for Arthritis Pain - Joint Pain Relief for Hand/Foot Pain, Knee/Elbow Pain & Ankle Pain - 1% - 5.29oz

9

Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

10

Boiron Arnicare Arthritis Cream for Pain Relief of Knees, Hands, Wrists, Elbows, Joints & Muscles – Quickly Absorbed & Fragrance-Free – 2.5 oz

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