10 Best topical anesthetics of 2025

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Best Choice

1

WELMATE
WELMATE | 5% Lidocaine | Numbing Cream Maximum Strength | Topical Anesthetic | Aches, Back Pain, Itching, Soreness, Burning, Tattoos, & Bruises | Unscented | Vegan | Child Resistant Packaging | 5.5 Oz
Main highlights

Maximum Strength Relief
Contains 5% Lidocaine, offering fast-acting, long-lasting pain relief for various discomforts.

Versatile Application
Ideal for aches, tattoos, injections, insect bites, and more.

Highly Praised Effectiveness
Customers commend its effectiveness in numbing and pain relief.
9.8

Exceptional

Our Rating

9.3
pain management

8.9
worth the money

8.2
Moisturizing
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Value for Money

2

Ebanel Laboratories
Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses
Main highlights

Fast-Acting Pain Relief
Ebanel 5 Lidocaine Spray offers immediate relief from pain, itching, and discomfort with its enhanced lidocaine and phenylephrine formula.

Versatile Use Cases
Ideal for tattoos, waxing, and minor skin irritations, providing temporary relief and comfort in sensitive areas.

Effective Numbing Experience
Customers praise its ability to significantly reduce pain during long tattoo sessions and other procedures.
9.5

Excellent

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
pain management
3

Ebanel
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
Main highlights

Fast-Acting Long-Lasting Relief
Ebanel 5 Lidocaine Cream provides quick, enduring numbing for pain relief and itch reduction.

Ideal for Skin Procedures
Perfect for tattoos, microneedling, waxing, and injections, enhancing comfort during sessions.

Highly Praised Numbing Effect
Customers commend its ability to significantly reduce discomfort and improve treatment experience.
9.4

Excellent

Our Rating

8.9
Simple to use

8.0
Absorbency

8.0
Gentle
4

HealthWise

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
9.3

Excellent

Our Rating
5

Bactine MAX
Bactine MAX First Aid Spray - Pain Relief Cleansing Spray with 4% Lidocaine - Numbing Lidocaine Kills 99.9% of Germs - Pain + Itch Relief For Minor Cuts & Scrapes, Burns & Bug Bites - 5oz

40% Off
Main highlights

Max Relief and Germ Protection
Bactine MAX provides pain and itch relief while killing 99% of germs.

Ideal for Minor Injuries
Perfect for cuts, scrapes, burns, bug bites, and sunburns.

No-Sting Application Praised
Customers appreciate the sting-free application, even on sensitive skin.
9.1

Excellent

Our Rating

9.7
Simple to use

9.3
pain management

8.7
Easy to grip
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6

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

34% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
8.8

Very Good

Our Rating

8.4
worth the money

8.4
pain management
7

DCH Labs
DCH Labs 5% Lidocaine Numbing Spray Maximum Strength Relief, 5 oz, Topical Anesthetic That Sprays at Any Angle, Vegan & Cruelty-Free, Secured with Child Resistant Cap
Main highlights

Maximum Strength Relief
5% lidocaine delivers fast relief for pain, itching, and soreness.

Versatile Use Cases
Ideal for anorectal disorders, tattoo aftercare, minor cuts, and more.

Reliable Spray Function
Customers praise the consistent performance of the spray mechanism.
8.7

Very Good

Our Rating

9.7
pain management

9.3
Simple to use

8.9
Odor elimination
8

Wuiil
HurriCaine Topical Anesthetic Gel Watermelon - 1 oz.
Main highlights

Fast Acting Pain Relief
HurriCaine Gel provides quick relief from oral discomfort with its fast-acting anesthetic properties.

Ideal for Dental Procedures
Perfect for numbing gums before dental work or alleviating minor mouth irritations.

Flavor Praised by Customers
The watermelon flavor is a favorite among users, making application pleasant.
8.6

Very Good

Our Rating
9

Americaine

Americaine Hospital Formula, Maximum Strength Benzocaine Topical Anesthetic Spray, For Minor Cuts, Scrapes, Burns & Sunburn, 2 oz Can (Packaging may vary)
8.5

Good

Our Rating
10

Jakwork
Maximum Strength Numbing Cream for Tattoos, Waxing, and Piercings - Topical Anesthetic Gel for Painless Tattooing, Microblading, Laser, and Skin Procedures
Main highlights

Deep Relief with Lidocaine
Infused with lidocaine for effective pain relief during tattoos, waxing, and piercings.

Versatile Use for Skin Procedures
Ideal for tattoos, laser removal, waxing, microblading, injections, and piercings.

Praised for Fast-Acting Formula
Customers love the quick numbing effect that starts within minutes.
8.4

Good

Our Rating

10 Best topical anesthetics of 2025

1

WELMATE | 5% Lidocaine | Numbing Cream Maximum Strength | Topical Anesthetic | Aches, Back Pain, Itching, Soreness, Burning, Tattoos, & Bruises | Unscented | Vegan | Child Resistant Packaging | 5.5 Oz

9.3

8.9

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

8.0

8.0

8.0

3

Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

8.9

8.0

8.0

4

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic

5

Bactine MAX First Aid Spray - Pain Relief Cleansing Spray with 4% Lidocaine - Numbing Lidocaine Kills 99.9% of Germs - Pain + Itch Relief For Minor Cuts & Scrapes, Burns & Bug Bites - 5oz

9.7

9.3

8.7

6

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

7

DCH Labs 5% Lidocaine Numbing Spray Maximum Strength Relief, 5 oz, Topical Anesthetic That Sprays at Any Angle, Vegan & Cruelty-Free, Secured with Child Resistant Cap

9.7

9.3

8.9

8

HurriCaine Topical Anesthetic Gel Watermelon - 1 oz.

9

Americaine Hospital Formula, Maximum Strength Benzocaine Topical Anesthetic Spray, For Minor Cuts, Scrapes, Burns & Sunburn, 2 oz Can (Packaging may vary)

10

Maximum Strength Numbing Cream for Tattoos, Waxing, and Piercings - Topical Anesthetic Gel for Painless Tattooing, Microblading, Laser, and Skin Procedures

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