10 Best suppositories of 2025

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Best Choice

1

Preparation H
PREPARATION H Hemorrhoid Symptom Treatment Suppositories, Burning, Itching and Discomfort Relief (48 Count)
Main highlights

Immediate Relief and Soothing Benefits
Provides prompt relief from burning, itching, and discomfort.

Ideal for Nighttime Relief
Can be used effectively at night for symptom relief.

Highly Soothing
Praised for its soothing effect and ease of use.
9.9

Exceptional

Our Rating

8.0
Simple to use

8.0
worth the money
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Value for Money

2

NutraBlast
NutraBlast Boric Acid Vaginal Suppositories - 100% Pure Made in USA - Boric Life Intimate Health Support (30 Count)

43% Off
Main highlights

Natural Support for Vaginal Health
Boric acid suppositories promote a healthy pH balance, supporting vaginal health naturally.

Effective for Post-Antibiotic Use
Ideal for restoring balance and freshness after antibiotic treatments.

Highly Praised for Immediate Relief
Customers appreciate the quick relief and freshness after just one use.
Key specs
- Usage:Vaginal discomfort support
- Formulation:Suppository capsules
- Active Ingredient:Boric acid
- Duration:7 consecutive days
- Dosage:1 capsule per day
9.8

Exceptional

Our Rating

9.5
Simple to use

8.9
Freshness
3

Fleet
Fleet Laxative Glycerin Suppositories for Adult Constipation, Adult Laxative Jar Aloe vera, 50 Count
Main highlights

Fast Effective Relief
Fleet Glycerin Suppositories provide quick relief from constipation in 15 minutes to 1 hour.

Ideal for Constipation Relief
Best used for occasional constipation, offering gentle, stimulant-free relief.

Quick Action Praised by Users
Customers frequently praise its rapid effectiveness, often working within minutes.
9.6

Exceptional

Our Rating

9.5
Simple to use

9.3
Comfort

9.1
worth the money
4

Amazon Basic Care
Amazon Basic Care Hemorrhoidal Suppositories, Relief from Burning, Itching and Discomfort of Hemorrhoids, 24 Count
Main highlights

Effective Relief from Hemorrhoid Discomfort
Amazon Basic Care Hemorrhoidal Suppositories provide fast relief from burning, itching, and swelling associated with hemorrhoids.

Ideal for Day and Night Use
These suppositories are designed for both daytime and nighttime relief, offering continuous protection from hemorrhoid discomfort.

Customers Praise Soothing Effect
Users frequently commend the product for its soothing effect on inflamed tissue, comparable to major brands.
Key specs
- active ingredients:cocoa butter, phenylephrine HCl
- application method:Rectal
- usage:Hemorrhoidal relief
- formulation:Suppository
- pain relief:Burning, itching, swelling
9.5

Excellent

Our Rating
5

AVEDANA
AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository
Main highlights

Fast and Gentle Relief
The Avedana constipation relief suppositories provide fast and gentle relief, alleviating discomfort within minutes and stimulating bowel movement in 15 minutes to one hour.

Efficient for Occasional Constipation
Ideal for those experiencing occasional constipation, these glycerin suppositories offer a safe and powerful laxative effect with a soothing and fast-acting formula.

Highly Recommended for Quick Results
Customers frequently praise the product for its quick and reliable action, noting it works better than stimulant laxatives without upsetting the stomach.
9.4

Excellent

Our Rating

9.9
pain management

9.5
Simple to use

9.3
Comfortable
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6

Dulcolax

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 4 Count

23% Off
9.3

Excellent

Our Rating
7

Rite Aid
Rite Aid Laxative Glycerin Suppositories, 2 g - 100 Count Adult Size | Constipation Relief | Works in Minutes for Gentle Effective Relief of Constipation | Hyperosmotic Laxative Suppository

23% Off
Main highlights

Quick Effective Relief
Provides gentle constipation relief in as fast as 15 minutes.

Ideal for Occasional Constipation
Perfect for those needing quick relief from occasional constipation.

Praised for Fast Action
Customers appreciate the fast-acting relief it provides.
Key specs
- Effectiveness:Works in minutes
- Form:Suppository
- Active Ingredient:Glycerin
- Dosage:2 grams
- Packaging:N/A
9.2

Excellent

Our Rating
8

Fleet Glycerin

Fleet Adult Glycerin Suppositories 50-Count (2-Pack)
9.1

Excellent

Our Rating
9

Fleet

Fleet Laxatives, Liquid Glycerin Suppositories for Adult Constipation Relief, 7.5 mL Bottles, 4 Count
8.8

Very Good

Our Rating
10

Monistat
Monistat 3 Day Yeast Infection Treatment for Women, 3 Miconazole Suppository Inserts & External Monistat Anti-Itch Cream Bundle

30% Off
Main highlights

Effective_3-Day_Treatment
Monistat 3-Day provides quick relief from yeast infection symptoms with miconazole nitrate.

Ideal_for_Convenient_Use
Perfect for women seeking a fast, hassle-free yeast infection solution.

Preferred_Suppository_Format
Customers love the easy-to-insert suppository format for comfort.
8.6

Very Good

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
Comfort

10 Best suppositories of 2025

1

PREPARATION H Hemorrhoid Symptom Treatment Suppositories, Burning, Itching and Discomfort Relief (48 Count)

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

NutraBlast Boric Acid Vaginal Suppositories - 100% Pure Made in USA - Boric Life Intimate Health Support (30 Count)

9.5

8.9

3

Fleet Laxative Glycerin Suppositories for Adult Constipation, Adult Laxative Jar Aloe vera, 50 Count

9.5

9.3

9.1

4

Amazon Basic Care Hemorrhoidal Suppositories, Relief from Burning, Itching and Discomfort of Hemorrhoids, 24 Count

5

AVEDANA USP 2g Glycerin Laxatives Suppository – 100 Adult Size Laxative Suppositories for Men and Women – Fast and Gentle Relief Suppositories for Constipation – Comfortable Shape Adult Suppository

9.9

9.5

9.3

6

Dulcolax Stimulant Laxative Medicated Suppositories, Predictable & Effective Constipation Relief, Bisacodyl 10 mg, 4 Count

7

Rite Aid Laxative Glycerin Suppositories, 2 g - 100 Count Adult Size | Constipation Relief | Works in Minutes for Gentle Effective Relief of Constipation | Hyperosmotic Laxative Suppository

8

Fleet Adult Glycerin Suppositories 50-Count (2-Pack)

9

Fleet Laxatives, Liquid Glycerin Suppositories for Adult Constipation Relief, 7.5 mL Bottles, 4 Count

10

Monistat 3 Day Yeast Infection Treatment for Women, 3 Miconazole Suppository Inserts & External Monistat Anti-Itch Cream Bundle

8.0

8.0

8.0

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