10 Best saline nasal sprays of 2025

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Best Choice

1

Vicks
Vicks Sinex SALINE Nasal Spray, Drug Free Ultra Fine Mist, Clear Everyday Sinus Congestion Fast, Clear Mucus from a Cold or Allergy, Daily Use 5.0 fl oz x 2
Main highlights

Drug-Free Relief
Provides fast, drug-free relief from nasal congestion using a hypertonic saline solution.

Ideal for Dry Environments
Perfect for alleviating nasal dryness in hot, dry, or windy conditions.

Gentle and Comfortable
Praised for its gentle mist that doesn't cause discomfort or irritation.
Key specs
- saline solution:Hypertonic saline solution
- features:Drug-free, ultra-fine mist
- product dimensions:4.17 x 2.09 x 7.08 inches
- active ingredients:Purified water
- usage instructions:Safe for daily use
9.8

Exceptional

Our Rating

8.4
Simple to use

8.0
worth the money

8.0
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Value for Money

2

Arm & Hammer
Simply Saline Extra Strength for Severe Congestion Relief Nasal Mist: 4.6oz 3-Pack

15% Off
Main highlights

Key Features
Features purified water, salt, and ARM & HAMMER Baking Soda in an extra-strength formula to alleviate sinus pressure and clear severe congestion.

Ideal Use Cases
Perfect for those suffering from allergies or colds, needing relief from nasal blockages, sinus pressure, and to flush out nasal irritants.

Customer Praise
Users highly appreciate its effectiveness in clearing congestion and the fact that it`s drug-free, allowing for frequent use alongside prescription medications.
Key specs
- saline solution:3 saline nasal spray
- features:Drug free, doctor recommended
- product dimensions:6.42 x 6.14 x 2.13 inches
- active ingredients:Purified water, salt, baking soda
- usage instructions:Use as often as needed
9.7

Exceptional

Our Rating
3

Amazon Basic Care
Amazon Basic Care Premium Saline Nasal Moisturizing Spray, 1.5 fl oz (Pack of 1), Clear

30% Off
Main highlights

Key Features
Contains sodium chloride 0.65% with preservatives, soothes dry nasal passages, and offers non-medicated relief.

Ideal Use Cases
Perfect for relieving dryness from allergies, sinus issues, and cold medications; instantly soothes.

Customer Reviews
Most praised for its effective relief of dry nasal passages and ease of use.
Key specs
- saline solution:Sodium chloride 0.65%
- features:Soothes dry nasal passages
- product dimensions:1.53 x 1.53 x 3.98 inches
- active ingredients:Sodium chloride, phenylcarbinol
- usage instructions:N/A
9.6

Exceptional

Our Rating

8.9
Simple to use

8.4
worth the money

8.2
Moisturizing
4

Arm & Hammer
ARM & HAMMER Simply Saline Nasal Care Daily Mist 4.5oz – Instant Relief for Every Day Congestion – One 4.5oz Bottle
Main highlights

Natural Moisturizing Formula
The isotonic formula naturally moistens dry nasal passages and clears congestion.

Ideal for Allergy Relief
Perfect for year-round allergies and common cold congestion relief.

Effortless Spray Mechanism
Customers love the easy push lever for consistent, gentle mist.
Key specs
- saline solution:Purified water, salt
- features:Moisturizes and relieves dryness
- product dimensions:2.1 x 2.1 x 6.3 inches
- active ingredients:ARM & HAMMER Baking Soda
- usage instructions:Use as often as needed
9.5

Excellent

Our Rating

8.9
Moisturizing

8.7
worth the money

8.7
Simple to use
5

Arm & Hammer

Arm & Hammer Simply Saline Daily Care Nasal Mist 4.4oz, Saline Nasal Spray, Drug-Free, 2-Pack
9.2

Excellent

Our Rating
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6

Little Remedies
Little Remedies Sterile Saline Nasal Mist, Safe for Newborns, 3 oz

17% Off
Main highlights

Relieves and Moisturizes Baby Noses
Relieves runny, stuffy, dry or crusty noses and keeps baby's nose clear and moisturized. Safe for newborns and contains no alcohol, drugs, or preservatives.

Ideal for Quick and Effective Nasal Relief
Sterile saline mist flushes mucus from little noses, providing non-medicated relief. Recommended by pediatricians and easy to use for fidgety babies.

Praised for Ease of Use and Effectiveness
Highly praised for its ease of use and effectiveness in clearing mucus. Many parents find it more efficient than other nasal sprays or drops.
Key specs
- effects:Flushes mucus, soothes
- safety:Safe for newborns
- active ingredient:Sterile saline
- usage:Relieves runny, stuffy noses
- formulation:Sterile saline mist
9.0

Excellent

Our Rating

9.7
Simple to use

9.5
worth the money

8.9
Vacuum strength
7

Thera Care
Thera Care Nasal Spray | Premium Saline | 1.5 fl oz | Non-Medicated Solution | Safe for Adults and Children | Allergy Relief
Main highlights

Immediate Relief for Dry Nasal Passages
Thera Care Nasal Spray provides instant moisture and relief for dry and irritated nasal passages with its saline solution.

Perfect for Allergy Sufferers
Ideal for flushing out pollen, dust, and debris, offering relief during allergy seasons.

Praised for Easy Application
Customers appreciate the spray bottle design for its even and thorough application.
Key specs
- effects:Soothes inflammation
- safety:Safe for daily use
- active ingredient:Saline salt water
- usage:Daily use on adults
- formulation:Spray bottle
8.9

Very Good

Our Rating
8

SinuCleanse
SinuCleanse Daily Care Sterile Saline Nasal Spray, Ultra Fine Mist, Instantly Moisturizes & Relieves Everyday Nasal Congestion Due to Colds & Dry Air, 4.5 Oz (2 Pack), Made in USA
Main highlights

Key Features and Benefits
Moisturizes dry nasal passages, aids in mucus removal, all-natural, preservative-free, and safe for all ages. Doctor recommended and FDA registered.

Ideal Use Cases
Excellent for relieving nasal congestion and sinus symptoms due to colds, allergies, dry air, and other irritants. Suitable for daily use.

Customer Reviews Highlight
Most praised for its instant relief of nasal discomfort, ease of use, and effectiveness in moisturizing dry nasal passages without side effects.
Key specs
- saline solution:Sterile Saline Nasal Mist
- features:Moisturizes, fast relief, preservative-free
- product dimensions:2.08 x 4.16 x 6.37 inches
- active ingredients:N/A
- usage instructions:Use as often as needed
8.7

Very Good

Our Rating
9

NeilMed

NeilMed NasaMist Hypertonic Extra Strength Saline Spray,Green 4.5 fl oz (Pack of 1)
8.5

Good

Our Rating

9.1
worth the money

8.7
Simple to use

8.7
Moisturizing
10

Arm & Hammer
ARM & HAMMER Simply Saline Daily Care Nasal Mist, Drug-Free Non-Drowsy Saline Spray for Instant Nasal Congestion and Allergy Relief, Use as Often as Needed, Suitable to Use if Pregnant, 1.6 oz
Main highlights

Key Features and Benefits
100% pure ingredients with isotonic formula; moisturizes dry nasal passages and clears congestion due to allergies or colds.

Ideal Use Cases
Perfect for alleviating dryness and congestion from year-round allergies, common colds, and as a companion to prescription or OTC medications.

Customer Reviews Highlight
Most praised for its effective congestion relief and gentle moisturizing, making it a go-to solution for allergy sufferers and cold patients.
8.4

Good

Our Rating

8.7
Simple to use

8.4
Comfort

8.0
worth the money

10 Best saline nasal sprays of 2025

1

Vicks Sinex SALINE Nasal Spray, Drug Free Ultra Fine Mist, Clear Everyday Sinus Congestion Fast, Clear Mucus from a Cold or Allergy, Daily Use 5.0 fl oz x 2

8.4

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Simply Saline Extra Strength for Severe Congestion Relief Nasal Mist: 4.6oz 3-Pack

3

Amazon Basic Care Premium Saline Nasal Moisturizing Spray, 1.5 fl oz (Pack of 1), Clear

8.9

8.4

8.2

4

ARM & HAMMER Simply Saline Nasal Care Daily Mist 4.5oz – Instant Relief for Every Day Congestion – One 4.5oz Bottle

8.9

8.7

8.7

5

Arm & Hammer Simply Saline Daily Care Nasal Mist 4.4oz, Saline Nasal Spray, Drug-Free, 2-Pack

6

Little Remedies Sterile Saline Nasal Mist, Safe for Newborns, 3 oz

9.7

9.5

8.9

7

Thera Care Nasal Spray | Premium Saline | 1.5 fl oz | Non-Medicated Solution | Safe for Adults and Children | Allergy Relief

8

SinuCleanse Daily Care Sterile Saline Nasal Spray, Ultra Fine Mist, Instantly Moisturizes & Relieves Everyday Nasal Congestion Due to Colds & Dry Air, 4.5 Oz (2 Pack), Made in USA

9

NeilMed NasaMist Hypertonic Extra Strength Saline Spray,Green 4.5 fl oz (Pack of 1)

9.1

8.7

8.7

10

ARM & HAMMER Simply Saline Daily Care Nasal Mist, Drug-Free Non-Drowsy Saline Spray for Instant Nasal Congestion and Allergy Relief, Use as Often as Needed, Suitable to Use if Pregnant, 1.6 oz

8.7

8.4

8.0

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