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10 Best puppy flea treatments of 2026

Save up to 18% off
  • Best Choice

    1

    Seresto Small Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Under 18 lbs. | 8 Months Protection
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    in the last week
    Seresto
    9.8
    Exceptional

    Seresto Small Dog Vet-Recommended Flea & Tick Treatment & Prevention Collar for Dogs Under 18 lbs. | 8 Months Protection

    • is discontinued by manufacturer:No
    • product dimensions:1.56 x 4.5 x 4.5 inches 3.52 ounces
    • asin:B00B8CG58U
    • date first available:January 28, 2013
    • department:Flea & Tick
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  • Value for Money

    2

    Advantage II Small Dog, 4 pack
    Advantage
    9.7
    Exceptional

    Advantage II Small Dog, 4 pack

    • manufacturer recommended age:1 month and up
    • is discontinued by manufacturer:No
    • product dimensions:6.5 x 1 x 4.25 inches 0.16 ounces
    • country of origin:Germany
    • asin:B004QRHSDU

  • 3

    PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
    PetArmor
    9.5
    Excellent

    PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)

    • manufacturer recommended age:N/A
    • is discontinued by manufacturer:No
    • product dimensions:4 x 0.5 x 2.5 inches 0.32 ounces
    • country of origin:USA
    • asin:B00WWP1U7I

  • 4

    PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
    PetArmor
    9.2
    Excellent

    PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (5-22 lbs)

    • manufacturer recommended age:N/A
    • is discontinued by manufacturer:No
    • product dimensions:1.33 x 5.74 x 6.75 inches 0.18 ounces
    • country of origin:USA
    • asin:B01N0BZUXO

  • 5

    Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses
    Capstar
    9.1
    Excellent

    Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

    • is discontinued by manufacturer:No
    • country of origin:Switzerland
    • asin:B07PXHQ5JR
    • date first available:July 5, 2015
    • item model number:CA4920Y07AMZ1
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  • 6

    FRONTLINE Plus Flea & Tick Spot Treatment for Small Breed Dogs 5-22 lbs. (Orange) Count of 3
    Frontline
    8.8
    Very Good

    FRONTLINE Plus Flea & Tick Spot Treatment for Small Breed Dogs 5-22 lbs. (Orange) Count of 3

    18% Off
    • manufacturer recommended age:1 month and up
    • is discontinued by manufacturer:No
    • product dimensions:5.75 x 0.75 x 4.5 inches; 0.16 ounces
    • country of origin:N/A
    • asin:B00008DFGY

  • 7

    K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 2-Mo Supply
    K9 Advantix
    8.7
    Very Good

    K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 2-Mo Supply

    • manufacturer recommended age:N/A
    • is discontinued by manufacturer:No
    • product dimensions:1 x 4.38 x 4.75 inches 0.8 ounces
    • country of origin:Germany
    • asin:B00I0BXQ6Q

  • 8

    K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply
    K9 Advantix
    8.5
    Good

    K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply

    • manufacturer recommended age:N/A
    • is discontinued by manufacturer:No
    • product dimensions:1 x 4.38 x 4.75 inches 0.32 ounces
    • country of origin:Germany
    • asin:B00I2266Y2

  • 9

    PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing in 30 Minutes, Small Dog Flea Treatment 2-25 lbs, 6 Doses
    PetArmor
    8.3
    Good

    PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing in 30 Minutes, Small Dog Flea Treatment 2-25 lbs, 6 Doses

    • is discontinued by manufacturer:N/A
    • country of origin:Switzerland
    • asin:B07GN2V7LR
    • date first available:August 19, 2018
    • item model number:711650110006

  • 10

    Amazon Basics Flea, Tick & Mosquito Topical Treatment & Prevention for Medium Dogs (11-20 pounds), Fast-Acting, Kills Fleas, Eggs & Larvae, 30 Day Protection, 6 Count, Packaging May Vary
    Amazon Basics
    8.0
    Good

    Amazon Basics Flea, Tick & Mosquito Topical Treatment & Prevention for Medium Dogs (11-20 pounds), Fast-Acting, Kills Fleas, Eggs & Larvae, 30 Day Protection, 6 Count, Packaging May Vary

    • manufacturer recommended age:N/A
    • is discontinued by manufacturer:N/A
    • product dimensions:1.4 x 4.27 x 6.5 inches 0.86 ounces
    • country of origin:USA
    • asin:B0842NW63Q

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