February 21, 2026

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10 Best puppy flea treatments of 2026

Save up to 16% off

1

K9 Advantix
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
Main highlights

30-Day Protection for Dogs 21-55 lbs
K9 Advantix II provides a 30-day treatment and prevention for fleas, ticks, mosquitoes, biting flies, and lice, suitable for dogs weighing 21-55 lbs.

Use Based on Dog's Weight
Ensure to purchase K9 Advantix II according to your dog's weight, not size, for effective flea and tick control. Ideal for suburban and rural areas.

Effective Flea and Tick Repellent
Customers praise K9 Advantix II for its effectiveness in repelling fleas and ticks, with noticeable results within 12 hours and long-lasting protection.
9.7

Exceptional

Our Rating

8.7
Simple to use

8.0
Aroma

8.0
worth the money
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2

K9 Advantix
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
Main highlights

30-Day Protection for Dogs 21-55 lbs
K9 Advantix II provides a 30-day treatment and prevention for fleas, ticks, mosquitoes, biting flies, and lice, suitable for dogs weighing 21-55 lbs.

Use Based on Dog's Weight
Ensure to purchase K9 Advantix II according to your dog's weight, not size, for effective flea and tick control. Ideal for suburban and rural areas.

Effective Flea and Tick Repellent
Customers praise K9 Advantix II for its effectiveness in repelling fleas and ticks, with noticeable results within 12 hours and long-lasting protection.
9.5

Excellent

Our Rating

8.7
Simple to use

8.0
Aroma

8.0
worth the money
3

PetArmor
PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
Main highlights

Effective Flea and Tick Protection
PetArmor Plus offers waterproof protection against fleas, ticks, and lice for up to 30 days.

Ideal for Active Dogs
Perfect for dogs 5-22 lbs who frequently go outdoors.

Highly Praised Long-Lasting Formula
Customers appreciate its ability to break the flea cycle and provide lasting protection.
9.3

Excellent

Our Rating

9.3
Water tight

8.2
Simple to use

8.0
Aroma
4

PetArmor
PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
Main highlights

Effective Flea and Tick Protection
PetArmor Plus offers waterproof protection against fleas, ticks, and lice for up to 30 days.

Ideal for Active Dogs
Perfect for dogs 5-22 lbs who frequently go outdoors.

Highly Praised Long-Lasting Formula
Customers appreciate its ability to break the flea cycle and provide lasting protection.
9.1

Excellent

Our Rating

9.3
Water tight

8.2
Simple to use

8.0
Aroma
5

K9 Advantix
K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 1-Mo Supply
Main highlights

Comprehensive Protection
Protects dogs 4-10 lbs. from fleas, ticks, mosquitoes, biting flies, and lice with a 30-day treatment.

Ideal for Small Dogs
Best for small dogs weighing between 4-10 lbs, providing easy topical application without a prescription.

Vet-Recommended Effectiveness
Praised for killing fleas within 12 hours and repelling pests on contact, ensuring dogs don't need to be bitten.
9.0

Excellent

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
Comfort
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6

K9 Advantix
K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 1-Mo Supply
Main highlights

Comprehensive Protection
Protects dogs 4-10 lbs. from fleas, ticks, mosquitoes, biting flies, and lice with a 30-day treatment.

Ideal for Small Dogs
Best for small dogs weighing between 4-10 lbs, providing easy topical application without a prescription.

Vet-Recommended Effectiveness
Praised for killing fleas within 12 hours and repelling pests on contact, ensuring dogs don't need to be bitten.
8.9

Very Good

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
Comfort
7

Capstar
Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses
Main highlights

Fast-Acting Flea Treatment
Capstar nitenpyram starts killing adult fleas in just 30 minutes.

Ideal for Small Dogs and Puppies
Safe for dogs 4 weeks and older, weighing 2-25 pounds.

Convenient No-Prescription Solution
Easy administration with no vet prescription needed, praised by customers.
Key specs
- Dog Weight Range:2-25 pounds
- Form:Oral
- Flea Action:Starts killing in 30 minutes
- Active Ingredient:Nitenpyram
- Dosage:57 mg
8.8

Very Good

Our Rating

8.2
Simple to use

8.0
simple to consume

8.0
Comfort
8

Capstar
Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses
Main highlights

Fast-Acting Flea Treatment
Capstar nitenpyram starts killing adult fleas in just 30 minutes.

Ideal for Small Dogs and Puppies
Safe for dogs 4 weeks and older, weighing 2-25 pounds.

Convenient No-Prescription Solution
Easy administration with no vet prescription needed, praised by customers.
Key specs
- Dog Weight Range:2-25 pounds
- Form:Oral
- Flea Action:Starts killing in 30 minutes
- Active Ingredient:Nitenpyram
- Dosage:57 mg
8.7

Very Good

Our Rating

8.2
Simple to use

8.0
simple to consume

8.0
Comfort
9

Frontline
FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

11% Off
Main highlights

Long-Lasting Protection
FRONTLINE Plus offers month-long protection against fleas, ticks, and lice with waterproof, fast-acting formula.

Ideal for Small Dogs
Perfect for dogs 5-22 lbs, ensuring safe and effective flea and tick control.

Highly Effective
Praised for consistent month-long effectiveness, even in challenging environments.
Key specs
- Active Ingredients:fipronil, S-methoprene
- Target Weight:5 pounds or more
- Application Method:topical
- Waterproof:Yes
- Treatment Duration:30 days
8.4

Good

Our Rating

8.2
Simple to take off

8.0
Simple to use

8.0
Aroma
10

Frontline
FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

16% Off
Main highlights

Long-Lasting Protection
FRONTLINE Plus offers month-long protection against fleas, ticks, and lice with waterproof, fast-acting formula.

Ideal for Small Dogs
Perfect for dogs 5-22 lbs, ensuring safe and effective flea and tick control.

Highly Effective
Praised for consistent month-long effectiveness, even in challenging environments.
Key specs
- Active Ingredients:fipronil, S-methoprene
- Target Weight:5 pounds or more
- Application Method:topical
- Waterproof:Yes
- Treatment Duration:30 days
8.1

Good

Our Rating

8.2
Simple to take off

8.0
Simple to use

8.0
Aroma

10 Best puppy flea treatments of 2026

1

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply

8.7

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply

8.7

8.0

8.0

3

PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)

9.3

8.2

8.0

4

PetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)

9.3

8.2

8.0

5

K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 1-Mo Supply

8.2

8.0

8.0

6

K9 Advantix II Small Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 4-10 lbs. | 1-Mo Supply

8.2

8.0

8.0

7

Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

8.2

8.0

8.0

8

Capstar (Nitenpyram) Fast-Acting Oral Flea Treatment for Dogs 2-25 Lbs, Vet-Recommended Medication Tablets, Flea Tablets for Dogs Start Killing in 30 Minutes, 6 Doses

8.2

8.0

8.0

9

FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

8.2

8.0

8.0

10

FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

8.2

8.0

8.0

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