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10 Best dog flea tick topical treatments of 2026
Save up to 21% off
Best Choice1
K9 AdvantixK9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 4-Mo Supply
Key specs-
is discontinued by manufacturer:No
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product dimensions:7.75 x 1 x 4.25 inches 2.08 ounces
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country of origin:Germany
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asin:B004QREOPU
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date first available:October 5, 2004
9.8Exceptional
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Value for Money2
K9 AdvantixK9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 4-Mo Supply
Key specs-
is discontinued by manufacturer:No
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product dimensions:7.75 x 1 x 4.25 inches 1.28 ounces
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country of origin:Germany
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asin:B004QMX4RY
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date first available:October 5, 2004
9.5Excellent
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3
PetArmorPetArmor Plus Flea and Tick Prevention for Dogs, Large Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting (45-88 lbs)
Key specs-
is discontinued by manufacturer:No
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product dimensions:1.33 x 5.74 x 6.75 inches 0.18 ounces
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country of origin:USA
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asin:B01N918D6E
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date first available:November 11, 2016
9.3Excellent
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4
PetArmorPetArmor Plus Flea and Tick Prevention for Dogs, Small Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (5-22 lbs)
Key specs-
is discontinued by manufacturer:No
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product dimensions:4 x 0.5 x 2.5 inches 0.32 ounces
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country of origin:USA
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asin:B00WWP1U7I
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date first available:September 27, 2017
9.1Excellent
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5
FrontlineFRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
21% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:5.75 x 0.75 x 4.5 inches 1.6 ounces
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country of origin:Germany
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asin:B0002J1FOE
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date first available:September 2, 2004
9.0Excellent
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6
PetArmorPetArmor Plus Flea and Tick Prevention for Dogs, Large Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting (45-88 lbs)
Key specs-
is discontinued by manufacturer:No
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product dimensions:4 x 0.5 x 2.5 inches 0.32 ounces
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country of origin:USA
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asin:B00WWP1MIK
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date first available:July 28, 2017
8.8Very Good
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7
Amazon BasicsAmazon Basics Preventative Flea and Tick Topical Treatment for Dogs, Large (45-88 lbs), Fast Acting and Long Lasting, 6 Counts, Packaging May Vary
Key specs-
is discontinued by manufacturer:N/A
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product dimensions:1.25 x 5.75 x 4.35 inches 1.45 ounces
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country of origin:USA
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asin:B07P22L3WV
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date first available:November 13, 2019
8.7Very Good
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8
FrontlineFRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
21% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:5.75 x 0.75 x 4.5 inches; 0.16 ounces
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country of origin:N/A
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asin:B00008DFGY
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date first available:October 2, 2001
8.4Good
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9
Amazon BasicsAmazon Basics Preventative Flea, Tick & Mosquito Topical Treatment for Medium Dogs (11-20 pounds), 6 Count, Packaging May Vary
Key specs-
is discontinued by manufacturer:N/A
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product dimensions:1.4 x 4.27 x 6.5 inches 0.86 ounces
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country of origin:USA
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asin:B0842NW63Q
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date first available:September 28, 2020
8.1Good
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10
FrontlineFRONTLINE Plus Flea and Tick Treatment for X-Large Dogs Up to 89 to 132 lbs. 3 Treatments
16% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:5.75 x 0.75 x 4.5 inches 1.6 ounces
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country of origin:France
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asin:B0002J1FP8
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date first available:May 30, 2004
8.0Good
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