10 Best pain relieving creams of 2025

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Best Choice

1

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
Main highlights

Powerful Topical Relief
Voltaren Gel offers prescription-strength arthritis pain relief, reducing stiffness and improving mobility.

Ideal for Joint Pain
Best for hand, wrist, elbow, ankle, foot, or knee pain relief.

Highly Praised Easy Cap
Customers appreciate the new easy-to-open cap for convenience.
9.9

Exceptional

Our Rating

9.3
pain management

8.0
worth the money
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Value for Money

2

VOLTAREN
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2

25% Off
Main highlights

Powerful Topical Relief
Voltaren Arthritis Pain Gel offers prescription-strength relief for arthritis, improving mobility and reducing stiffness with a non-greasy formula.

Ideal for Arthritis Pain
Perfect for hand, wrist, elbow, ankle, foot, and knee pain relief when used up to four times daily.

Doctor Recommended Effectiveness
Customers praise its effectiveness, often noting significant relief and satisfaction with results.
9.6

Exceptional

Our Rating
3

RUGBY LABORATORIES
Rugby Maximum Strength Pain Relieving Cream - Made with Menthol and Methyl Salicylate - Offers Temporary Joint and Muscle Soreness Relief - 3 Oz. (2 Pack)

11% Off
Main highlights

Key Features and Benefits
Features Menthol and Methyl Salicylate for dual action relief, targeting minor muscle and joint pain with a powerful, fast-acting formula.

Ideal Use Cases
Perfect for those suffering from arthritis, backache, strains, and sprains, providing temporary relief and improving daily comfort.

Customer Reviews Highlight
Users often praise its effectiveness in providing quick pain relief, highlighting its potency and ease of use as top benefits.
9.5

Excellent

Our Rating

9.5
pain management

9.3
worth the money
4

Bengay
Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

15% Off
Main highlights

Ultra-Strong Relief
Contains camphor, menthol, and methyl salicylate for effective pain relief.

Ideal for Minor Pains
Perfect for backaches, arthritis, muscle, joint pain, and bruises.

Menthol Scent Praised
Menthol scent is strong but effective for pain relief.
9.4

Excellent

Our Rating

8.4
worth the money

8.2
Aroma

8.0
pain management
5

Boiron
Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz

33% Off
Main highlights

Natural Pain Relief and Fast Absorption
Boiron Arnicare Gel offers temporary relief for muscle pain and stiffness with a fast-absorbing, non-greasy formula.

Ideal for Post-Workout and Minor Injuries
Perfect for soothing muscle soreness and reducing bruising after intense workouts, minor injuries, or overexertion.

Highly Praised Non-Sticky Application
Customers appreciate the gel's quick absorption and non-sticky, residue-free finish.
9.2

Excellent

Our Rating

9.3
Aroma

8.9
worth the money

8.7
Long life
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6

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

34% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
8.9

Very Good

Our Rating

8.4
worth the money

8.4
pain management
7

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Comfort for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

16% Off
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
8.8

Very Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients
8

Nervive
Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz
Main highlights

Powerful Pain Relief
Contains Lidocaine and Menthol for maximum strength relief from nerve pain.

Comprehensive Nerve Care
Ideal for relieving pain in toes, feet, fingers, hands, legs, and arms.

Fast Acting Formula
Customers praise its quick action, working in less than 5 minutes.
8.6

Very Good

Our Rating

8.0
worth the money

8.0
pain management
9

Tylenol
Tylenol Maximum Strength 4% Lidocaine Pain Relieving Cream for Back, Knee & Joints - Penetrating, Fragrance Free, 4oz

26% Off
Main highlights

Maximum Strength Lidocaine
Provides targeted, penetrating pain relief with maximum strength lidocaine.

Ideal for Joint and Muscle Pain
Perfect for back, knee, shoulder, and other joint pains.

Easy Application
Rollerball applicator praised for its ease of use.
8.4

Good

Our Rating
10

Biofreeze
Biofreeze Pain Relief Cream, Knee & Lower Back Pain Relief, Sore Muscle Relief, Neck Pain Relief, Shoulder Pain Relief, Muscle Recovery, FSA Eligible, 3 OZ Biofreeze Menthol Cream
Main highlights

Fast Acting Pain Relief
Biofreeze Cream provides quick, long-lasting relief for sore muscles, backaches, and joint pain with a non-greasy, moisturizing formula.

Ideal for Active Lifestyles
Perfect for athletes, travelers, and those needing on-the-go pain relief with TSA-approved 3 oz. jar.

Mild Menthol Fragrance Praised
Customers appreciate the subtle menthol scent, noting its effectiveness without overwhelming odor.
8.2

Good

Our Rating

9.5
Simple to use

8.7
pain management

8.2
worth the money

10 Best pain relieving creams of 2025

1

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

9.3

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2

3

Rugby Maximum Strength Pain Relieving Cream - Made with Menthol and Methyl Salicylate - Offers Temporary Joint and Muscle Soreness Relief - 3 Oz. (2 Pack)

9.5

9.3

4

Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

8.4

8.2

8.0

5

Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz

9.3

8.9

8.7

6

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

7

Penetrex Joint & Muscle Therapy - Soothing Comfort for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

8

Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz

8.0

8.0

9

Tylenol Maximum Strength 4% Lidocaine Pain Relieving Cream for Back, Knee & Joints - Penetrating, Fragrance Free, 4oz

10

Biofreeze Pain Relief Cream, Knee & Lower Back Pain Relief, Sore Muscle Relief, Neck Pain Relief, Shoulder Pain Relief, Muscle Recovery, FSA Eligible, 3 OZ Biofreeze Menthol Cream

9.5

8.7

8.2

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