10 Best pain relief sprays of 2025

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Best Choice

1

Biofreeze
Biofreeze Professional Strength Pain Relief Aerosol Spray, Arthritis Pain Reliever, Knee & Lower Back Pain Relief, Sore Muscle Relief, FSA Eligible, 2 Pack (4 FL OZ Biofreeze Menthol Spray)
Main highlights

Key Features
Fast-acting, cooling menthol relief for minor aches, with upside-down spray technology. Clinician recommended, animal-friendly, NSAID-free.

Ideal Use Cases
Perfect for backache, arthritis, strains, bruises, sprains, and hard-to-reach areas like the middle back, neck, and lower extremities.

Customer Praise
Users highly value its quick pain relief and the convenience of the 360 spray bottle, especially for reaching difficult areas.
9.8

Exceptional

Our Rating

9.1
pain management

8.7
worth the money

8.4
Long life
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Value for Money

2

Aleve
AleveX Pain Relieving Spray, Fast Acting & Fast Drying for Targeted Pain Relief, 3.2 oz Spray
Main highlights

Powerful Topical Pain Relief
Made with Camphor and maximum strength Menthol 16, providing fast-acting, long-lasting relief for minor muscle and joint aches.

Ideal for Active Lifestyles
Perfect for those experiencing arthritis, backaches, strains, sprains, and bruises, especially beneficial for physically active individuals.

Fast Acting and Effective
Customers consistently praise the product's immediate pain relief and ease of use, highlighting its effectiveness and convenience.
9.6

Exceptional

Our Rating

9.3
pain management

8.9
Simple to use

8.4
Long life
3

Aspercreme
Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.
Main highlights

Key Features
Max Strength Lidocaine for muscle, joint, and back pain relief. Odor-free, fast-acting, and dries quickly. Non-greasy and works at any angle.

Ideal Use Cases
Perfect for athletes, seniors, or anyone seeking quick pain relief in muscles and joints without the mess or smell.

Customer Reviews
Most praised for its quick pain relief and convenience. Users love the odor-free formula and how it doesn`t leave hands or skin greasy.
9.5

Excellent

Our Rating

9.1
Simple to use

8.0
worth the money

8.0
pain management
4

Biofreeze
Biofreeze Menthol Spray 3 FL OZ Colorless Aerosol Spray for Pain Relief associated with Sore Muscles, Arthritis, Simple Backaches, and Joint Pain
Main highlights

Key Features and Benefits
Clinician-recommended, fast-acting menthol formula with 360 spray technology for hard-to-reach areas; FSA/HSA eligible and not tested on animals.

Ideal Use Cases
Perfect for relieving minor aches and pains of muscles and joints associated with backache, strains, bruises, and sprains.

Customer Reviews Highlight
Most praised for its quick pain relief and ease of use, especially the continuous flow spray design for reaching difficult areas.
9.3

Excellent

Our Rating

8.9
pain management

8.0
Simple to use

8.0
Long life
5

Icy Hot

Icy Hot Original Pain Relief Dry Spray with 16% Menthol, Pain Relief for Muscles & Joints, 4 oz.
9.2

Excellent

Our Rating
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6

TIDL
TIDL Cryotherapy Pain Relief Spray, 3 Oz, Targeted Neck Pain, Joint & Muscle Pain Relief, Organic, Plant-Based Menthol, Instant Cooling for Arthritis, Back & Knee Pain
Main highlights

Fast-Acting and Potent Pain Relief
Our Plant-Powered Cryotherapy Spray offers rapid relief for muscle and joint pain using all-natural, plant-based ingredients.

Ideal for Post-Workout Recovery
Perfect for athletes and those with active lifestyles, providing comprehensive relief from inflammation, back pain, arthritis, and muscle soreness.

Easy and Effective Application
Customers appreciate the 360-Degree Spray Technology for even coverage and the cooling effect without stickiness, despite some complaints about the strong smell.
9.1

Excellent

Our Rating

9.3
pain management

8.9
Simple to use

8.0
Aroma
7

Dermoplast
Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

13% Off
Main highlights

Fast Pain and Itch Relief
Dermoplast provides quick relief from minor cuts, burns, and bug bites with hospital-strength Benzocaine.

Ideal for Postpartum and Family Use
Perfect for postpartum care and soothing children's minor injuries, offering no-touch application.

Highly Effective and Easy to Use
Customers praise its instant cooling effect and versatility for various skin irritations.
9.0

Excellent

Our Rating

9.7
Simple to use

9.1
worth the money

8.9
pain management
8

Bactine MAX
Bactine MAX First Aid Spray - Cleansing Spray with 4% Lidocaine - Relief for Minor Cuts, Burns & Bug Bites - 5oz
Main highlights

Max Relief and Germ Protection
Bactine MAX provides pain and itch relief while killing 99% of germs.

Ideal for Minor Injuries
Perfect for cuts, scrapes, burns, bug bites, and sunburns.

No-Sting Application Praised
Customers appreciate the sting-free application, even on sensitive skin.
8.9

Very Good

Our Rating

9.7
Simple to use

9.3
pain management

8.7
Easy to grip
9

Icy Hot

Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces
8.7

Very Good

Our Rating
10

BLUE-EMU

Blue-Emu Continuous Pain Relief Spray for Fast-Acting Joint & Muscle Relief, 4 Oz, 1 Pack

34% Off
8.6

Very Good

Our Rating

10 Best pain relief sprays of 2025

1

Biofreeze Professional Strength Pain Relief Aerosol Spray, Arthritis Pain Reliever, Knee & Lower Back Pain Relief, Sore Muscle Relief, FSA Eligible, 2 Pack (4 FL OZ Biofreeze Menthol Spray)

9.1

8.7

8.4

How do we rank?

How do we rank?

Analyzing top stores

2

AleveX Pain Relieving Spray, Fast Acting & Fast Drying for Targeted Pain Relief, 3.2 oz Spray

9.3

8.9

8.4

3

Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.

9.1

8.0

8.0

4

Biofreeze Menthol Spray 3 FL OZ Colorless Aerosol Spray for Pain Relief associated with Sore Muscles, Arthritis, Simple Backaches, and Joint Pain

8.9

8.0

8.0

5

Icy Hot Original Pain Relief Dry Spray with 16% Menthol, Pain Relief for Muscles & Joints, 4 oz.

6

TIDL Cryotherapy Pain Relief Spray, 3 Oz, Targeted Neck Pain, Joint & Muscle Pain Relief, Organic, Plant-Based Menthol, Instant Cooling for Arthritis, Back & Knee Pain

9.3

8.9

8.0

7

Dermoplast Pain, Burn & Itch Relief Spray for Minor Cuts, Burns and Bug Bites, 2.75 Oz (Packaging May Vary)

9.7

9.1

8.9

8

Bactine MAX First Aid Spray - Cleansing Spray with 4% Lidocaine - Relief for Minor Cuts, Burns & Bug Bites - 5oz

9.7

9.3

8.7

9

Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces

10

Blue-Emu Continuous Pain Relief Spray for Fast-Acting Joint & Muscle Relief, 4 Oz, 1 Pack

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