Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best pain creams of 2025
Save up to 49% off
   - Home
 - Health & Household
 - Products
 - Health care
 - Over-the-counter medication
 - Pain relievers
 - Joint & muscle pain relief
 - Treatments
 - Pain relief rubs
 
- Best Choice
1
                        
                    SombraSombra Warm Pain Relief Gel, Warm Relief for Arthritis and Chronic Pain Pre-Workout Muscle Rub Vegan Formula Free of Artificial Fragrances, Dyes, NSAIDs, Wax, Petroleum, Alcohol - 8oz Jar
Main highlights- 
                        Absorbs quickly with a refreshing orange scent, offering non-greasy and non-staining relief.
Quick Absorption and Orange Scent
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                        Perfect for relieving minor muscle and joint aches associated with arthritis and backaches.
Ideal for Muscle and Joint Pain
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                        Customers love the warming sensation that loosens tightness and eases pain.
Praised for Warming Effect
 
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 - Value for Money
2
                        
                    VoltarenVoltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
19% OffMain highlights- 
                        Voltaren Gel offers prescription-strength arthritis pain relief, reducing stiffness and improving mobility.
Powerful Topical Relief
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                        Best for hand, wrist, elbow, ankle, foot, or knee pain relief.
Ideal for Joint Pain
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                        Customers appreciate the new easy-to-open cap for convenience.
Highly Praised Easy Cap
 
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 3
BoironBoiron Arnicare Gel for Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz
33% OffMain highlights- 
                        Boiron Arnicare Gel offers temporary relief for muscle pain and stiffness with a fast-absorbing, non-greasy formula.
Natural Pain Relief and Fast Absorption
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                        Perfect for soothing muscle soreness and reducing bruising after intense workouts, minor injuries, or overexertion.
Ideal for Post-Workout and Minor Injuries
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                        Customers appreciate the gel's quick absorption and non-sticky, residue-free finish.
Highly Praised Non-Sticky Application
 
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 4
VoltarenVoltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
Main highlights- 
                        Voltaren Gel provides prescription-strength relief for arthritis pain, improving mobility and reducing stiffness without the need for pills.
Powerful Topical Pain Relief
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                        Best used for hand, wrist, elbow, ankle, foot, or knee pain with significant relief in seven days.
Ideal for Joint Pain Management
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                        Customers praise its effectiveness as a topical pain reliever, often noting its significant impact within a few uses.
Highly Effective According to Users
 
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 5
PenetrexPenetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Main highlights- 
                        Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.
Deep Penetration Relief
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                        Perfect for back, neck, hands, feet, and more.
Versatile Application Areas
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                        Customers praise its healing properties over mere pain relief.
Healing Over Pain Relief
 
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 6
AspercremeAspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.
34% OffMain highlights- 
                        Contains 4% lidocaine for quick, effective pain relief.
Fast-Acting Numbing Relief
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                        Perfect for arthritis, backaches, sprains, and strains.
Ideal for Joint and Muscle Pain
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                        Customers love its ease of application and effectiveness.
Praised for Ease of Use
 
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 7
BoironBoiron Arnicare Cream for Joint Pain, Muscle Pain, Swelling, Soreness, Stiffness, and Bruises - Fast Absorbing and Fragrance-Free - 4.2 oz
27% OffMain highlights- 
                        Boiron Arnicare Cream provides fast-absorbing, non-greasy relief for muscle pain, stiffness, and swelling from bruises.
Natural Pain Relief
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                        Perfect for athletes, busy parents, and anyone with minor injuries or overexertion.
Ideal for Active Lifestyles
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                        Customers love its effectiveness in quickly healing bruises and reducing swelling.
Praised for Quick Healing
 
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 8
BulbHeadBulbHead As Seen On TV Hempvana Original Relief Cream Maximum Strength, The Hemp Cream for Muscle Joint Back Knee Shoulder Neck Elbow Hand Foot
Main highlights- 
                        Contains Trolamine Salicylate 10% and hemp seed extract for fast pain relief and skin moisture.
Maximum Strength Relief
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                        Targets arthritis, muscle strains, backaches, and more for temporary relief.
Ideal for Joint and Muscle Pain
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                        Praised for its fast absorption and ease of use by customers.
Easy Application and Quick Absorption
 
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 9
BiofreezeBiofreeze Pain Relief Cream for Knee, Neck, Hip, Joint, Shoulder, & Simple Backache, Arthritis Pain Reliever, Sore Muscle Relief, Cooling Menthol Pain Cream, 3 Oz
Main highlights- 
                        Biofreeze Cream provides quick, long-lasting relief for sore muscles, backaches, and joint pain with a non-greasy, moisturizing formula.
Fast Acting Pain Relief
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                        Perfect for athletes, travelers, and those needing on-the-go pain relief with TSA-approved 3 oz. jar.
Ideal for Active Lifestyles
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                        Customers appreciate the subtle menthol scent, noting its effectiveness without overwhelming odor.
Mild Menthol Fragrance Praised
 
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 10
NerviveNervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz
49% OffMain highlights- 
                        Contains Lidocaine and Menthol for maximum strength relief from nerve pain.
Powerful Pain Relief
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                        Ideal for relieving pain in toes, feet, fingers, hands, legs, and arms.
Comprehensive Nerve Care
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                        Customers praise its quick action, working in less than 5 minutes.
Fast Acting Formula
 
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