10 Best pain creams of 2025

Save up to 34% off

Best Choice

1

Hempvana
Hempvana Cream, Ultra Strength Lidocaine Relief of Sore Muscles, AS-SEEN-ON-TV, Achy Knees, and More. Odor-Free & Enriched with Hemp Seed Oil, 4-oz jar
Main highlights

Ultra Strength Pain Relief
Contains 4% lidocaine for effective muscle and arthritis pain relief.

Targeted Pain Application
Ideal for sore muscles and achy knees, providing localized relief.

Quick Absorption
Praised for non-greasy, fast absorption with hemp seed oil benefits.
9.7

Exceptional

Our Rating

8.9
worth the money

8.4
pain management
How do we rank?

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Based on millions of stores and reviews

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Value for Money

2

VOLTAREN
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2

25% Off
Main highlights

Powerful Topical Relief
Voltaren Arthritis Pain Gel offers prescription-strength relief for arthritis, improving mobility and reducing stiffness with a non-greasy formula.

Ideal for Arthritis Pain
Perfect for hand, wrist, elbow, ankle, foot, and knee pain relief when used up to four times daily.

Doctor Recommended Effectiveness
Customers praise its effectiveness, often noting significant relief and satisfaction with results.
9.4

Excellent

Our Rating
3

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Comfort for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

16% Off
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
9.3

Excellent

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients
4

Boiron
Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz

32% Off
Main highlights

Natural Pain Relief and Fast Absorption
Boiron Arnicare Gel offers temporary relief for muscle pain and stiffness with a fast-absorbing, non-greasy formula.

Ideal for Post-Workout and Minor Injuries
Perfect for soothing muscle soreness and reducing bruising after intense workouts, minor injuries, or overexertion.

Highly Praised Non-Sticky Application
Customers appreciate the gel's quick absorption and non-sticky, residue-free finish.
9.1

Excellent

Our Rating

9.3
Aroma

8.9
worth the money

8.7
Long life
5

Bengay
Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

15% Off
Main highlights

Ultra-Strong Relief
Contains camphor, menthol, and methyl salicylate for effective pain relief.

Ideal for Minor Pains
Perfect for backaches, arthritis, muscle, joint pain, and bruises.

Menthol Scent Praised
Menthol scent is strong but effective for pain relief.
9.0

Excellent

Our Rating

8.4
worth the money

8.2
Aroma

8.0
pain management
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6

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

34% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
8.7

Very Good

Our Rating

8.4
worth the money

8.4
pain management
7

VOLTAREN
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube
Main highlights

Powerful Topical Pain Relief
Voltaren Gel provides prescription-strength relief for arthritis pain, improving mobility and reducing stiffness without the need for pills.

Ideal for Joint Pain Management
Best used for hand, wrist, elbow, ankle, foot, or knee pain with significant relief in seven days.

Highly Effective According to Users
Customers praise its effectiveness as a topical pain reliever, often noting its significant impact within a few uses.
8.6

Very Good

Our Rating

8.0
pain management

8.0
worth the money
8

Voltaren
Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g
Main highlights

Powerful Topical Relief
Voltaren Gel offers prescription-strength arthritis pain relief, reducing stiffness and improving mobility.

Ideal for Joint Pain
Best for hand, wrist, elbow, ankle, foot, or knee pain relief.

Highly Praised Easy Cap
Customers appreciate the new easy-to-open cap for convenience.
8.5

Good

Our Rating

9.3
pain management

8.0
worth the money
9

Biofreeze
Biofreeze Pain Relief Cream, Knee & Lower Back Pain Relief, Sore Muscle Relief, Neck Pain Relief, Shoulder Pain Relief, Muscle Recovery, FSA Eligible, 3 OZ Biofreeze Menthol Cream
Main highlights

Fast Acting Pain Relief
Biofreeze Cream provides quick, long-lasting relief for sore muscles, backaches, and joint pain with a non-greasy, moisturizing formula.

Ideal for Active Lifestyles
Perfect for athletes, travelers, and those needing on-the-go pain relief with TSA-approved 3 oz. jar.

Mild Menthol Fragrance Praised
Customers appreciate the subtle menthol scent, noting its effectiveness without overwhelming odor.
8.3

Good

Our Rating

9.5
Simple to use

8.7
pain management

8.2
worth the money
10

Advil
Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz
Main highlights

Fast Relief Formula
Unique blend with four powerful ingredients for quick pain relief.

Ideal for Muscle and Joint Pain
Perfect for relieving muscle, joint, and back pain without a prescription.

Pleasant Minty Scent
Praised for its subtle mint fragrance that doesn't linger.
8.2

Good

Our Rating

10 Best pain creams of 2025

1

Hempvana Cream, Ultra Strength Lidocaine Relief of Sore Muscles, AS-SEEN-ON-TV, Achy Knees, and More. Odor-Free & Enriched with Hemp Seed Oil, 4-oz jar

8.9

8.4

How do we rank?

How do we rank?

Analyzing top stores

2

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 100 g x 2

3

Penetrex Joint & Muscle Therapy - Soothing Comfort for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

4

Boiron Arnicare Gel for Soothing Relief of Joint Pain, Muscle Pain, Muscle Soreness, and Swelling from Bruises or Injury - Non-greasy and Fragrance-Free - 2.6 oz

9.3

8.9

8.7

5

Bengay Ultra Strength Topical Pain Relief Cream, Non-Greasy Topical Analgesic for Minor Arthritis, Muscle, Joint and Back Pain, Camphor, Menthol and Methyl Salicylate, 4 OZ

8.4

8.2

8.0

6

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

7

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac, No Prescription Needed - 1.7 oz/50 g Tube

8.0

8.0

8

Voltaren Arthritis Pain Gel for Powerful Topical Arthritis Pain Relief with Diclofenac - NEW Easy Open Cap - 150 g

9.3

8.0

9

Biofreeze Pain Relief Cream, Knee & Lower Back Pain Relief, Sore Muscle Relief, Neck Pain Relief, Shoulder Pain Relief, Muscle Recovery, FSA Eligible, 3 OZ Biofreeze Menthol Cream

9.5

8.7

8.2

10

Advil Targeted Relief Pain Relieving Cream, Up to 8 Hours of Powerful Relief of Minor Arthritis Pain, Joint Pain, Lower Back Pain and Muscle Pain - 2.3 oz

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