Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best over counter sore throat medicines of 2025
Save up to 21% off
Best Choice1
VicksVICKS NyQuil Cold & Flu Relief Over-the-Counter Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 48 LiquiCaps
9.9Exceptional
Our Rating
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Value for Money2
MucinexMucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz
19% Off9.7Exceptional
Our Rating
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3
TylenolTylenol Extra Strength Severe Cough + Sore Throat Day & Night Caplets, Combo Pack for Powerful Multi-Symptom Relief for Painful Sore Throat & Cough, Acetaminophen Pain Reliever, 24 ct
17% Off9.6Exceptional
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4
MucinexMucinex Maximum Strength Fast-Max Cold, Flu, & Sore Throat Liquid Gels, 16ct, Controls Cough, Thins & Loosens Mucus, Relieves Nasal & Chest Congestion, Headache & Fever
21% Off9.3Excellent
Our Rating
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5
VicksVicks VapoCool Severe Medicated Sore Throat Drops, Max Strength Menthol, Soothes Sore Throat Pain, Cherry Flavor, 45ct
9.1Excellent
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6
ChlorasepticChloraseptic Sore Throat Spray, Menthol, 6 oz
9.0Excellent
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7
BoironBoiron ThroatCalm On The Go Travel Essential for Pain Relief from Red, Dry, Scratchy, Sore Throats and Hoarseness - 2 Count (160 Pellets)
8.9Very Good
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8
VicksVICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
15% Off8.7Very Good
Our Rating
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9
VicksVicks NyQuil Cold & Flu Relief Over-the-Counter Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 24 Liquicaps
8.6Very Good
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10
TylenolTylenol Extra Strength Severe Cough + Sore Throat Caplets, Daytime Extra Strength Pain Reliever & Fever Reducer + Cough Suppressant, Acetaminophen 500 mg, Dextromethorphan HBr 15 mg, 24 ct
8.5Good
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