10 Best over counter flu medicines of 2025

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Best Choice

1

Boiron
Boiron Oscillococcinum Homeopathic Medicine for flu-Like Symptoms, White, 36 Count
Main highlights

Homeopathic Relief for Flu Symptoms
Oscillococcinum helps relieve fatigue, headache, body aches, chills, and fever.

Ideal for Family Use
Safe and easy for all family members, ages 2 and up.

Convenient and Easy to Use
Praised for its ease of use and effectiveness by customers.
9.9

Exceptional

Our Rating

9.9
Simple to use

9.9
Flavor

9.7
worth the money
How do we rank?

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Based on millions of stores and reviews

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Value for Money

2

Vicks
Vicks DayQuil Severe Cold & Flu Liquid Medicine, Daytime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Chest Congestion, Stuffy Nose, Nasal Congestion, Sinus Pressure, & Cough, 2x12oz
Main highlights

Powerful Multi-Symptom Relief
DayQuil SEVERE alleviates cough, congestion, body pain, and more.

Daytime Cold and Flu Solution
Perfect for maintaining daily activities despite cold or flu.

Fast-Acting Formula
Customers praise its quick relief from cold and flu symptoms.
9.8

Exceptional

Our Rating
3

Mucinex
Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

19% Off
Main highlights

Powerful Multi-Symptom Relief
Provides maximum strength relief for cold and flu symptoms, including sore throat, cough, and congestion.

Ideal for Severe Cold and Flu
Perfect for adults experiencing severe cold and flu symptoms, day or night.

Highly Effective Liquid Formula
Customers praise the liquid formula for its fast-acting relief and pleasant grape flavor.
9.6

Exceptional

Our Rating

8.7
Flavor

8.7
worth the money

8.0
Simple to use
4

Vicks
VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquid Medicine Co-Pack, Powerful Multi-Symptom Daytime & Nighttime Relief for Cold, Cough, and Flu Symptoms, Sugar & Alcohol Free, 2x8oz
Main highlights

Specially Formulated for High Blood Pressure
Decongestant-free cold and flu relief suitable for those with high blood pressure.

Ideal for Day and Night Use
Provides effective symptom relief both during the day and at night.

Effective Multi-Symptom Relief
Praised for easing fever, aches, cough, and providing restful sleep.
9.5

Excellent

Our Rating

9.9
simple to consume

9.3
pain management

9.3
Flavor
5

Vicks
VICKS NyQuil Cold & Flu Relief Over-the-Counter Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 48 LiquiCaps
Main highlights

Powerful Multi-Symptom Relief
NyQuil provides fast relief for headache, fever, sore throat, sneezing, and cough.

Ideal for Nighttime Use
Perfect for nighttime use to alleviate cold and flu symptoms and ensure restful sleep.

Cost-Effective and Convenient
Highly praised for its cost-effectiveness and convenience, especially with Subscribe and Save.
9.4

Excellent

Our Rating

9.1
worth the money

9.1
Flavor

8.9
simple to consume
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6

Mucinex
Mucinex Fast-Max Max Strength Cold and Flu Medicine for Adults, Daytime Cold Medicine, Over-the-Counter Medication With Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 20 Caplets
Main highlights

Multi-Symptom Relief
Mucinex Fast-Max provides powerful relief for 9 cold and flu symptoms, including cough, sore throat, and congestion.

Ideal for Busy Adults
Perfect for adults needing quick symptom relief to manage daily tasks even when sick.

Highly Praised Efficacy
Customers consistently praise its effectiveness and quick relief from cold and flu symptoms.
9.3

Excellent

Our Rating
7

Mucinex
Mucinex Fast-Max Severe Congestion & Cough Medicine, Maximum Strength Symptom Relief, Over-The-Counter Medication, Cold Medicine, Cough Suppressant, Expectorant, Nasal Decongestant, FSA/HSA, 6 FL OZ

22% Off
Main highlights

Powerful Multi-Symptom Relief
Maximum Strength Mucinex Fast-Max provides relief for cough, chest congestion, and nasal congestion with a triple-action formula.

Ideal for Severe Cold Symptoms
Best used for severe congestion, persistent cough, and excess mucus for adults 12+ years.

Highly Effective Cough Suppressant
Praised for its ability to provide quick relief from persistent coughing, enabling restful sleep.
9.2

Excellent

Our Rating

9.3
quality of sleep

9.1
worth the money

8.9
Flavor
8

Vicks

Vicks DayQuil and NyQuil VapoCOOL SEVERE Combo Cold & Flu + Congestion Medicine, Max Strength Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Cough, 48 Count - 32 DayQuil, 16 NyQuil
9.1

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
9

Vicks

Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 24 Liquicaps
9.0

Excellent

Our Rating
10

Quality Choice
Quality Choice Adult Nighttime Cough Medicine, Cherry Flavored Night Time Cold and Flu Relief, Cough Syrup for Runny Nose & Sneezing, for Better Sleep, 8oz Bottle of Cherry Liquid Medicine
Main highlights

Key Features
Fast relief for cough, runny nose, sneezing; contains Dextromethorphan Hbr and Doxylamine Succinate. Ideal for nighttime use.

Ideal Use Cases
Best for adults and children 12+ needing relief from cold, flu symptoms, and throat/bronchial irritation overnight.

Customer Praise
Highly praised for its effectiveness in improving sleep quality by reducing cough and cold symptoms.
8.9

Very Good

Our Rating

10 Best over counter flu medicines of 2025

1

Boiron Oscillococcinum Homeopathic Medicine for flu-Like Symptoms, White, 36 Count

9.9

9.9

9.7

How do we rank?

How do we rank?

Analyzing top stores

2

Vicks DayQuil Severe Cold & Flu Liquid Medicine, Daytime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Chest Congestion, Stuffy Nose, Nasal Congestion, Sinus Pressure, & Cough, 2x12oz

3

Mucinex Fast-Max Cold and Flu & Nightshift Severe Cold and Flu Medicine for Adults, Over-the-Counter Medication Combo Pack for Sore Throat Relief, Decongestant, Cough & Cold Medicines, 2 x 6 Fl Oz

8.7

8.7

8.0

4

VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquid Medicine Co-Pack, Powerful Multi-Symptom Daytime & Nighttime Relief for Cold, Cough, and Flu Symptoms, Sugar & Alcohol Free, 2x8oz

9.9

9.3

9.3

5

VICKS NyQuil Cold & Flu Relief Over-the-Counter Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 48 LiquiCaps

9.1

9.1

8.9

6

Mucinex Fast-Max Max Strength Cold and Flu Medicine for Adults, Daytime Cold Medicine, Over-the-Counter Medication With Acetaminophen, Dextromethorphan HBr, Guaifenesin, Phenylephrine HCl, 20 Caplets

7

Mucinex Fast-Max Severe Congestion & Cough Medicine, Maximum Strength Symptom Relief, Over-The-Counter Medication, Cold Medicine, Cough Suppressant, Expectorant, Nasal Decongestant, FSA/HSA, 6 FL OZ

9.3

9.1

8.9

8

Vicks DayQuil and NyQuil VapoCOOL SEVERE Combo Cold & Flu + Congestion Medicine, Max Strength Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Cough, 48 Count - 32 DayQuil, 16 NyQuil

8.9

8.7

8.2

9

Vicks NyQuil Cold and Flu Relief Liquid Medicine, Powerful Multi-Symptom Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches and Pains, Sneezing, Runny Nose, and Cough, 24 Liquicaps

10

Quality Choice Adult Nighttime Cough Medicine, Cherry Flavored Night Time Cold and Flu Relief, Cough Syrup for Runny Nose & Sneezing, for Better Sleep, 8oz Bottle of Cherry Liquid Medicine

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