10 Best otc medicine for sore throats of 2025

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1

Vicks
Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct
Main highlights

Fast Multi-Symptom Relief
Vicks DayQuil and NyQuil provide rapid relief from cold and flu symptoms, including headache, fever, sore throat, and cough.

Daytime and Nighttime Use
DayQuil is ideal for daytime activities, while NyQuil ensures restful sleep at night, offering 24-hour symptom management.

Customer Satisfaction
Customers praise the effectiveness of NyQuil for sleep and DayQuil for maintaining productivity while sick.
9.8

Exceptional

Our Rating

9.1
Flavor

9.1
worth the money
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Based on millions of stores and reviews

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Value for Money

2

Vicks

VICKS DayQuil & NyQuil Elderberry Flavor Cold & Flu Liquid Medicine Co-Pack, Multi-Symptom Relief of Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 2x12oz
9.7

Exceptional

Our Rating
3

Mucinex
Mucinex Instasoothe Sore Throat Relief, Throat Numbing Spray Starts to Work On Contact, Sore Throat Pain Medicine, Relieves Pain associated with Sore Throat, Cherry Flavor Throat Spray, 3.8 Fl Oz
Main highlights

Fast Acting Relief
Mucinex Instasoothe provides rapid sore throat relief with benzocaine and menthol.

Ideal for Sore Throats and Canker Sores
Perfect for temporary relief of sore throats, sore mouth, and canker sores.

Effective Numbing Action
Customers praise its strong numbing effect, reducing throat pain quickly.
9.4

Excellent

Our Rating

8.0
worth the money

8.0
Flavor
4

Mucinex
Mucinex Instasoothe Sore Throat Relief Drops, Sore Throat Lozenges, Sore Throat Medicine with Hexylresorcinol, Cough Drops Alternative, Honey & Echinacea Flavor Medicated Numbing Throat Drops, 40 ct
Main highlights

Fast Acting Pain Relief
Clinically proven to numb sore throat pain quickly with a 3-in-1 formula that relieves, soothes, and numbs.

Ideal for Severe Sore Throats
Perfect for those experiencing intense throat pain needing fast, long-lasting relief.

Effective Pain Numbing
Customers praise its ability to alleviate throat pain effectively and quickly.
9.3

Excellent

Our Rating

8.0
worth the money

8.0
Flavor
5

Mucinex
Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

29% Off
Main highlights

Multi-Symptom Relief Efficiency
Provides fast, powerful relief for 9 cold and flu symptoms.

Ideal for Day and Night Use
Designed for comprehensive symptom management, both day and night.

Quick Symptom Relief Praised
Customers appreciate the fast-acting relief, often within two doses.
9.1

Excellent

Our Rating

9.7
quality of ingredients

9.5
pain management

8.0
simple to consume
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6

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

15% Off
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
8.9

Very Good

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
7

Contac
Contac Cold & Flu Medicine, Non-Drowsy, Powerful Multi-Symptom Daytime Relief for Nasal Congestion, Sinus Pressure, Headache, Fever, Sore Throat, Minor Aches and Pains, 24 Caplets
Main highlights

Maximum Strength Symptom Relief
Provides relief for nasal congestion, sinus pressure, aches, and fever.

Ideal for Daytime Cold and Flu
Perfect for managing symptoms without drowsiness during the day.

Highly Praised by Customers
Users appreciate its effectiveness and availability through online retailers.
8.7

Very Good

Our Rating

9.7
pain management

8.9
worth the money

8.4
For traveling
8

Vicks
VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, RelievesHeadache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz
Main highlights

Maximum Strength Relief
Provides powerful relief for 9 cold and flu symptoms with real honey flavor.

Day and Night Use
Ideal for treating symptoms any time with non-drowsy DayQuil and restful NyQuil.

Honey Flavor Praised
Most users appreciate the honey flavor for better taste compared to traditional options.
8.5

Good

Our Rating

8.0
worth the money

8.0
Flavor
9

Vicks

Vicks NyQuil SEVERE Cold and Flu Relief Liquid Berry Flavored Medicine, Maximum Strength, 9-Symptom Nighttime Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Sneezing, Cough, 12 FL OZ
8.4

Good

Our Rating

9.1
worth the money

9.1
Flavor
10

Vicks
Vicks DayQuil and NyQuil Combo Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime And Nighttime Relief For Headache, Fever, Sore Throat, Cough, 24 Count, 16 DayQuil, 8 NyQuil Liquicaps
Main highlights

Key Features
Offers fast, powerful relief for both day and night, targeting multiple cold and flu symptoms with non-drowsy DayQuil and NyQuil formulas.

Ideal Use Cases
Best used when needing to maintain daytime activity without drowsiness and achieving restful sleep at night despite cold and flu symptoms.

Customer Praise
Most reviews highlight the fast-acting relief and effectiveness in alleviating a wide range of symptoms, appreciating the day and night support.
8.3

Good

Our Rating

9.1
worth the money

9.1
Flavor

10 Best otc medicine for sore throats of 2025

1

Vicks DayQuil & NyQuil Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 72ct

9.1

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

VICKS DayQuil & NyQuil Elderberry Flavor Cold & Flu Liquid Medicine Co-Pack, Multi-Symptom Relief of Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 2x12oz

3

Mucinex Instasoothe Sore Throat Relief, Throat Numbing Spray Starts to Work On Contact, Sore Throat Pain Medicine, Relieves Pain associated with Sore Throat, Cherry Flavor Throat Spray, 3.8 Fl Oz

8.0

8.0

4

Mucinex Instasoothe Sore Throat Relief Drops, Sore Throat Lozenges, Sore Throat Medicine with Hexylresorcinol, Cough Drops Alternative, Honey & Echinacea Flavor Medicated Numbing Throat Drops, 40 ct

8.0

8.0

5

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

9.7

9.5

8.0

6

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

7

Contac Cold & Flu Medicine, Non-Drowsy, Powerful Multi-Symptom Daytime Relief for Nasal Congestion, Sinus Pressure, Headache, Fever, Sore Throat, Minor Aches and Pains, 24 Caplets

9.7

8.9

8.4

8

VICKS DayQuil & NyQuil SEVERE Honey Flavor Co-Pack, Cold & Flu Medicine, RelievesHeadache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, 2x12oz

8.0

8.0

9

Vicks NyQuil SEVERE Cold and Flu Relief Liquid Berry Flavored Medicine, Maximum Strength, 9-Symptom Nighttime Relief For Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Sneezing, Cough, 12 FL OZ

9.1

9.1

10

Vicks DayQuil and NyQuil Combo Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime And Nighttime Relief For Headache, Fever, Sore Throat, Cough, 24 Count, 16 DayQuil, 8 NyQuil Liquicaps

9.1

9.1

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