Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best otc medicinal sleep aids of 2026
Save up to 17% off
Best Choice1
Unisom9.6Exceptional
Unisom Nighttime Sleep-Aid Gels, Diphenhydramine HCI 50mg, 100 Count, 2 pk
17% Off
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Value for Money2
ZzzQuil9.3Excellent
ZzzQuil LiquiCap Sleep Aid, Diphenhydramine 25mg HCl, Sleep Aids for Adults, Nighttime Sleep Aid, 72 LiquiCaps
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is discontinued by manufacturer:No
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product dimensions:5.24 x 1.5 x 3.74 inches 0.48 ounces
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country of origin:Canada
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asin:B01M2CZMOS
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date first available:February 28, 2013
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3
Unisom9.2Excellent
Unisom SleepTabs, Nighttime Sleep-aid, Doxylamine Succinate, 80 Tablets
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is discontinued by manufacturer:No
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product dimensions:1.75 x 3.06 x 3.13 inches; 1.06 ounces
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country of origin:N/A
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asin:B01683HFGY
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date first available:October 6, 2015
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4
KIRKLAND SIGNATURE8.9Very Good
Kirkland Signature Nighttime Sleep Aid (Doxylamine Succinate 25 Mg), 96 Tablets (Pack of 4)
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is discontinued by manufacturer:No
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product dimensions:3 x 3 x 3 inches 3.2 ounces
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country of origin:N/A
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asin:B005C4ZVQW
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date first available:December 26, 2014
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5
ZzzQuil8.8Very Good
ZzzQuil, Sleep Aid, Nighttime Sleep Aid Liquid, 50 mg Diphenhydramine HCl, Fall Asleep Fast, Non-Habit Forming, Warming Berry Flavor, 12 FL OZ (Pack of 2)
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is discontinued by manufacturer:No
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product dimensions:5.25 x 2.63 x 6.88 inches 1.56 Pounds
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country of origin:USA
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asin:B007OSBYRY
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date first available:March 26, 2012
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6
A+Health8.7Very Good
A+Health Nighttime Sleep Aid Diphenhydramine 50mg Softgels, Maximum Strength, 160 Count
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is discontinued by manufacturer:N/A
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product dimensions:2 x 2 x 4.25 inches 3.68 ounces
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country of origin:USA
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asin:B093ML2TLT
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date first available:April 27, 2021
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7
Rite Aid8.6Very Good
Rite Aid Natural Sleep Aid Caplets, Diphenhydramine HCl, 25mg - 200 Count | Sleeping Pills for Adults Extra Strength
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is discontinued by manufacturer:No
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product dimensions:N/A
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country of origin:USA
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asin:B07T26RMVN
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date first available:June 12, 2019
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8
Tylenol8.4Good
Tylenol Simply Sleep Nighttime Sleep Aid Caplets, 25 mg Diphenhydramine HCl, Non-Habit Forming Sleep Aid for Adults, 100 Count
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is discontinued by manufacturer:No
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product dimensions:20 x 40 x 20 inches 0.32 ounces
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country of origin:USA
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asin:B0014C2JQ6
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date first available:March 11, 2010
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9
ZzzQuil8.2Good
ZzzQuil Liquid Sleep Aid, Soothing Sleep, Diphenhydramine 50mg HCl, Chamomile Honey Flavored, Nighttime Sleep Aid Liquid, Sleep Aids for Adults, 2 Pack, 24 FL OZ
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is discontinued by manufacturer:N/A
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product dimensions:N/A
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country of origin:USA
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asin:B0CQDGFZKH
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date first available:December 16, 2023
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10
Unisom8.1Good
Unisom SleepGels, Diphenhydramine HCl 50 mg, 60 Count
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is discontinued by manufacturer:No
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product dimensions:1.81 x 3.06 x 3.5 inches 2 ounces
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country of origin:N/A
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asin:B0074395XY
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date first available:November 2, 2011
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