10 Best otc medications treatments in the US

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Last Updated - April 26, 2024

Best Choice

1

Nexium

Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules For All-Day And All-Night Protection From Frequent Heartburn, Heartburn Medicine With Esomeprazole Magnesium - 42 Count

21% Off
9.9

Exceptional

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.9
simple to consume

9.5
Flavor

9.1
worth the money
More info

Why we love it

Nexium blocks acid at the source for complete heartburn protection

Esomeprazole magnesium delayed release capsules shut down stomachs active acid pumps

Nexium is the number 1 choice of doctors for their own frequent heartburn
Value for Money

2

Amazon Basic Care

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)
9.8

Exceptional

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.9
simple to consume

9.3
Flavor

9.3
worth the money
- Amazon
- Walmart
More info

Why we love it

The active ingredient, omeprazole, reduces acid to treat frequent heartburn.

It is a 14

day course of treatment, taken once every 24 hours.
3

Imodium

Imodium Multi-Symptom Relief Caplets with Loperamide Hydrochloride and Simethicone, Anti-Diarrheal Medicine for Treatment of Diarrhea, Gas, Bloating, Cramps & Pressure, 24 ct.

47% Off
9.7

Exceptional

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.1
worth the money

8.2
Flavor
More info

Why we love it

24 count package

Combines loperamide HCl simethicone

Treats diarrhea gas related symptoms
4

Ohm

Ohm Omeprazole Tablets, Delayed-Release Tablets, 20mg Acid Reducer, 42 Tablets
9.6

Exceptional

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
- Amazon
More info

Why we love it

Treats heartburn that happens often

Reduces stomach acid

Delayed release tablets let medicine work over time
5

AZO

AZO Urinary Pain Relief Maximum Strength | Fast relief of UTI Pain, Burning & Urgency | Targets Source of Pain | #1 Most Trusted Brand | 24 Tablets
9.5

Excellent

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.9
simple to consume

9.3
worth the money

9.3
pain management
More info

Why we love it

AZO Urinary Pain Relief relieves UTI pain, burning and urgency in as little as 20 minutes.

1 choice of doctors and recommended by pharmacists specifically for urinary discomfort.

1 most trusted brand for over the counter urinary pain relief.
6

Imodium

Imodium A-D Diarrhea Relief Caplets with Loperamide Hydrochloride, Anti-Diarrheal Medicine to Help Control Symptoms of Diarrhea Due to Acute, Active & Traveler's Diarrhea, 24 ct.

31% Off
9.3

Excellent

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.1
simple to consume

8.7
worth the money

8.2
Flavor
- Amazon
- Walmart
More info

Why we love it

The product contains loperamide HCl, which has been proven to be effective in controlling and treating diarrhea symptoms.

It works with your body to slow down your system and help restore its natural rhythm and balance.

The product is available in convenient tear away packaging and is suitable for use both at home and on the go.
7

URISTAT

Uristat Ultra UTI Pain Relief Tablets, Fast Urinary Tract Infection Relief of Urinary Pain, Burning, Urgency, Maximum Strength, Cranberry Flavored Coating, 30 Tablets

31% Off
9.2

Excellent

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.3
worth the money

9.3
pain management

9.1
Flavor
More info

Why we love it

Fast relief of UTI pain

Contains recommended OTC ingredient

Easy to swallow tablet
8

Sudafed

Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 24 ct

25% Off
8.9

Very Good

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.1
simple to consume

8.4
worth the money

8.0
Comfort
More info

Why we love it

Powerful relief of sinus pain, pressure, and congestion

Also relieves nasal congestion from allergies and the common cold

Maximum strength formula can be used by adults and children 12
9

Imodium

Imodium A-D Anti-Diarrheal Medicine Softgels with 2 mg Loperamide Hydrochloride per Capsule, Diarrhea Relief to Help Control Symptoms Due to Acute, Active & Traveler's Diarrhea, 24 ct.

39% Off
8.8

Very Good

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

9.7
simple to consume

9.3
Flavor

8.9
worth the money
10

Anbesol

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)

12% Off
8.7

Very Good

Our Rating

Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.

8.9
worth the money

8.4
pain management

8.0
Flavor
- Amazon
- Walmart
More info

Why we love it

Fast relief from mouth and gum pain

Maximum strength formula

Easy to use

10 Best otc medications treatments in the US

1

Nexium 24HR ClearMinis Acid Reducer Heartburn Relief Delayed Release Capsules For All-Day And All-Night Protection From Frequent Heartburn, Heartburn Medicine With Esomeprazole Magnesium - 42 Count

9.9

9.5

9.1

Why we love it

2

Amazon Basic Care Omeprazole Delayed Release Tablets 20 mg, Treats Frequent Heartburn, Acid Reducer, Heartburn Medicine, 42 Count (Pack of 1)

9.9

9.3

9.3

Why we love it

3

Imodium Multi-Symptom Relief Caplets with Loperamide Hydrochloride and Simethicone, Anti-Diarrheal Medicine for Treatment of Diarrhea, Gas, Bloating, Cramps & Pressure, 24 ct.

9.1

8.2

Why we love it

4

Ohm Omeprazole Tablets, Delayed-Release Tablets, 20mg Acid Reducer, 42 Tablets

Why we love it

5

AZO Urinary Pain Relief Maximum Strength | Fast relief of UTI Pain, Burning & Urgency | Targets Source of Pain | #1 Most Trusted Brand | 24 Tablets

9.9

9.3

9.3

Why we love it

6

Imodium A-D Diarrhea Relief Caplets with Loperamide Hydrochloride, Anti-Diarrheal Medicine to Help Control Symptoms of Diarrhea Due to Acute, Active & Traveler's Diarrhea, 24 ct.

9.1

8.7

8.2

Why we love it

7

Uristat Ultra UTI Pain Relief Tablets, Fast Urinary Tract Infection Relief of Urinary Pain, Burning, Urgency, Maximum Strength, Cranberry Flavored Coating, 30 Tablets

9.3

9.3

9.1

Why we love it

8

Sudafed PE Sinus Congestion Maximum Strength Non-Drowsy Decongestant Tablets, 24 ct

9.1

8.4

8.0

Why we love it

9

Imodium A-D Anti-Diarrheal Medicine Softgels with 2 mg Loperamide Hydrochloride per Capsule, Diarrhea Relief to Help Control Symptoms Due to Acute, Active & Traveler's Diarrhea, 24 ct.

9.7

9.3

8.9

10

Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)

8.9

8.4

8.0

Why we love it

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