10 Best otc flu medicines of 2025

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1

Vicks

VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquicap 48ct Co-Pack, Powerful Multi Symptom Daytime & Nighttime Medicine for Cold, Cough, and Flu Symptoms, 24ct DayQuil, 24ct NyQuil
9.8

Exceptional

Our Rating
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Value for Money

2

Vicks
Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief
Main highlights

Maximum Strength 9-Symptom Relief
NyQuil SEVERE provides fast relief for 9 cold and flu symptoms, including cough, fever, and congestion.

Ideal for Nighttime Cold Relief
Designed to help you sleep by alleviating symptoms that keep you awake.

Praised for Effective Symptom Relief
Customers love NyQuil SEVERE for its reliable and quick symptom relief.
9.6

Exceptional

Our Rating

9.3
worth the money

9.1
Flavor
3

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

15% Off
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.4

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
4

Mucinex
Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

19% Off
Main highlights

Multi-Symptom Relief Efficiency
Provides fast, powerful relief for 9 cold and flu symptoms.

Ideal for Day and Night Use
Designed for comprehensive symptom management, both day and night.

Quick Symptom Relief Praised
Customers appreciate the fast-acting relief, often within two doses.
9.2

Excellent

Our Rating

9.7
quality of ingredients

9.5
pain management

8.0
simple to consume
5

Vicks
VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquid Medicine Co-Pack, Powerful Multi-Symptom Daytime & Nighttime Relief for Cold, Cough, and Flu Symptoms, Sugar & Alcohol Free, 2x8oz

17% Off
Main highlights

Specially Formulated for High Blood Pressure
Decongestant-free cold and flu relief suitable for those with high blood pressure.

Ideal for Day and Night Use
Provides effective symptom relief both during the day and at night.

Effective Multi-Symptom Relief
Praised for easing fever, aches, cough, and providing restful sleep.
9.1

Excellent

Our Rating

9.9
simple to consume

9.3
pain management

9.3
Flavor
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6

Tylenol

Tylenol Day & Night Cold & Flu Multi-Symptom Liquid Gels Combo Pack, Cold & Flu Relief Medicine, Pain Reliever & Fever Reducer + Cough Suppressant & Antihistamine, 24 ct
8.8

Very Good

Our Rating
7

Contac
Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets
Main highlights

Maximum Strength Relief
Provides maximum strength relief for cold and flu symptoms.

Day and Night Use
Ideal for continuous relief with separate day and night formulas.

Customer Praised Effectiveness
Highly praised for relieving nasal congestion and body aches.
8.6

Very Good

Our Rating
8

Vicks

VICKS DayQuil & NyQuil Elderberry Flavor Cold & Flu Liquid Medicine Co-Pack, Multi-Symptom Relief of Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 2x12oz
8.5

Good

Our Rating
9

Tylenol
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

28% Off
Main highlights

Comprehensive Symptom Relief
Relieves fever, pain, congestion, cough, and loosens mucus.

Ideal for Cold and Flu
Perfect for adults and children 12+ with cold and flu symptoms.

Praised Effectiveness
Customers appreciate its superior efficacy over generic alternatives.
8.4

Good

Our Rating

9.9
pain management

9.3
worth the money

8.7
simple to consume
10

Coricidin HBP
Coricidin HBP Maximum Strength Multi-Symptom Flu Tablets For Body Aches, Body Pains Cold and Cough Relief: Flu Medicine for Adults with High Blood Pressure - 24 Count
Main highlights

Decongestant-Free Symptom Relief
Provides flu relief without elevating blood pressure, ideal for adults with hypertension.

Ideal for Seasonal Flu
Perfect for managing seasonal flu symptoms, including body aches and cough.

Praised for Blood Pressure Safety
Customers appreciate its safety for high blood pressure sufferers.
8.3

Good

Our Rating

10 Best otc flu medicines of 2025

1

VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquicap 48ct Co-Pack, Powerful Multi Symptom Daytime & Nighttime Medicine for Cold, Cough, and Flu Symptoms, 24ct DayQuil, 24ct NyQuil

How do we rank?

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Analyzing top stores

2

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.3

9.1

3

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

4

Mucinex Fast-Max Day Cold and Flu & Night Cold and Flu Medicine for Adults, Day/Night Combo Pack for Fever, Sore Throat Relief, Decongestant, Cough & Cold Medicines, 24 Fast-Dissolving Liquid Gels

9.7

9.5

8.0

5

VICKS DayQuil & NyQuil High Blood Pressure Cold & Flu Relief Liquid Medicine Co-Pack, Powerful Multi-Symptom Daytime & Nighttime Relief for Cold, Cough, and Flu Symptoms, Sugar & Alcohol Free, 2x8oz

9.9

9.3

9.3

6

Tylenol Day & Night Cold & Flu Multi-Symptom Liquid Gels Combo Pack, Cold & Flu Relief Medicine, Pain Reliever & Fever Reducer + Cough Suppressant & Antihistamine, 24 ct

7

Contac Non-Drowsy Day & Multi-Symptom Night Cold & Flu Medicine, Maximum Strength Relief for Fever, Sore Throat, Nasal Congestion, Head & Body Aches, Runny Nose, 28 Count, 16 Day, 12 Night Caplets

8

VICKS DayQuil & NyQuil Elderberry Flavor Cold & Flu Liquid Medicine Co-Pack, Multi-Symptom Relief of Headache, Fever, Sore Throat, Minor Aches & Pains, Sneezing, Runny Nose, and Cough, 2x12oz

9

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

9.9

9.3

8.7

10

Coricidin HBP Maximum Strength Multi-Symptom Flu Tablets For Body Aches, Body Pains Cold and Cough Relief: Flu Medicine for Adults with High Blood Pressure - 24 Count

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