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10 Best otc flea meds of 2025
Save up to 30% off
Best Choice1
AdvantageAdvantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 6-Month Supply
Key specs-
Target Weight:Over 9 lbs
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Application Method:Topical treatment
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Duration:30 days
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Kill Time:Within 12 hours
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Fragrance:Fragrance-free
9.8Exceptional
Our Rating
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Value for Money2
FrontlineFRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
11% Off9.7Exceptional
Our Rating
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3
Amazon BasicsAmazon Basics Flea and Tick Topical Treatment for Small Dogs (5-22 pounds), 3 Count (Previously Solimo)
9.6Exceptional
Our Rating
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4
WoyamayWoyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
Key specs-
Target Weight:Small, medium, large dogs
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Active Ingredients:Coconut oil, flaxseed, yeast
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Application Method:Oral chews
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Treatment Duration:Over 3 months
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Protection Type:Flea and tick prevention
9.5Excellent
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5
CarmelieOral Flea and Tick Support for Dogs and Cats, Natural Dog Flea and Tick Defense, Cat Flea Drops Supplements with Vitamin for Pets - All Breeds and Ages - Bacon
26% OffKey specs-
Target Weight:Up to 75+ lbs
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Application Method:Oral drops
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Duration:1-2 times daily
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Kill Time:N/A
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Fragrance:Bacon flavor
9.3Excellent
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6
CheristinCheristin Flea Treatment & Prevention for Cats | Fast acting topical flea treatment for cats over 1.8 lbs | 1 Count
Key specs-
Target Weight:1.8 lbs and up
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Application Method:Topical
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Duration:6 weeks
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Kill Time:30 minutes
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Fragrance:N/A
9.2Excellent
Our Rating
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7
Amazon BasicsAmazon Basics Flea and Tick Topical Treatment for Large Dogs (45-88 pounds), Unscented, 3 Count (Previously Solimo)
9.1Excellent
Our Rating
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8
PetArmorPetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large Dogs (45-88 lbs)
14% Off8.8Very Good
Our Rating
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9
CapstarCapstar(nitenpyram) for Dogs Fast-Acting Oral Flea Treatment for Dogs 2-25 lbs, Vet-Recommended Medication Tablets Start Killing in 30 Minutes, 6 Doses
Key specs-
Dog Weight Range:2-25 pounds
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Form:Oral
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Flea Action:Starts killing in 30 minutes
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Active Ingredient:Nitenpyram
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Dosage:57 mg
8.5Good
Our Rating
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10
Amazon BasicsAmazon Basics Cat Flea Treatment, Topical Solution for Large Cats Over 9 Pounds, 6 Count
30% Off8.4Good
Our Rating
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