July 1, 2025

Advertising Disclosure

10 Best otc cold medicines of 2025

Save up to 33% off

Best Choice

1

Beekeeper's Naturals
Beekeeper's Naturals Kids Propolis Throat Spray 95% Bee Propolis Extract - Natural Immune Support & Sore Throat Relief, Antioxidants & Gluten-Free, 1.06 oz (Pack of 2)
Main highlights

Powerful Natural Immune Support
Propolis Throat Spray for Kids offers natural immune support with bee propolis, antioxidants, and is alcohol-free, pesticide-free, and sustainably sourced.

Ideal for Soothing Dry Throats
Perfect for kids and adults needing throat relief and immune support, especially during travel or seasonal changes.

Praised for Great Taste
Customers love the taste, making it easy for kids to use regularly; also appreciated for effective throat soothing and immune boosting.
9.8

Exceptional

Our Rating

9.7
Simple to use

9.3
Flavor

8.9
For traveling
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

GenCare
GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies

23% Off
Main highlights

Fast Relief with Guaifenesin
GenCare Mucus Relief contains 400mg Guaifenesin to thin mucus, easing breathing and expelling phlegm.

Effective for Colds and Flu
Ideal for combatting chest congestion, mucus, and bronchial secretions caused by colds and flu.

Cost-Effective Alternative
Praised for being more affordable than Mucinex, with similar active ingredients and effectiveness.
Key specs
- form:Tablets
- active ingredient:Guaifenesin
- target age:12 years and up
- symptom relief:Mucus and phlegm
- flavor:N/A
9.7

Exceptional

Our Rating

8.9
worth the money

8.7
simple to consume

8.0
Flavor
3

Boiron
Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count

25% Off
Main highlights

Comprehensive Flu Symptom Relief
Oscillococcinum helps relieve fatigue, headache, body aches, chills, and fever safely for ages 2 and up.

Ideal for Early Flu Onset
Best used at the first sign of flu-like symptoms to reduce duration and severity.

Customer Praised Quick Dissolving
Sweet-tasting pellets dissolve easily under the tongue, praised for convenience.
9.5

Excellent

Our Rating

9.7
simple to consume

9.7
Simple to use

9.7
Flavor
4

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

15% Off
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.3

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
5

Amazon Basic Care
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

33% Off
Main highlights

Maximum Strength Multi-Symptom Relief
Provides around-the-clock relief for cold and flu symptoms with a combination of daytime and nighttime caplets.

Ideal for Families and Busy Individuals
Perfect for those needing effective relief during the day and restful sleep at night.

Highly Praised Nighttime Formula
Customers appreciate the nighttime caplets for aiding sleep and symptom relief.
9.1

Excellent

Our Rating

9.3
simple to consume

9.1
worth the money

8.7
Flavor
See Today’s Deals & Prices
6

Mucinex
Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

21% Off
Main highlights

Maximum Strength Relief
Provides relief from pain, headache, nasal, sinus, and chest congestion.

Ideal for Severe Congestion
Best for adults experiencing severe sinus and nasal congestion.

Praised for Effectiveness
Customers appreciate the product's good results despite small packaging.
9.0

Excellent

Our Rating
7

Zicam
Zicam Cold Remedy Zinc Medicated Fruit Drops, Assorted Flavors, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count
Main highlights

Cold Shortening Benefit
Zicam Zinc Medicated Fruit Drops are designed to shorten cold duration when taken at the first sign of symptoms.

Ideal for Early Symptoms
Best used at the onset of a cold, such as first sniffle or sore throat.

Zinc Content Praised
Customers appreciate the zinc content for its effectiveness in managing cold symptoms.
8.8

Very Good

Our Rating

9.5
Flavor

9.1
worth the money
8

Tylenol
Tylenol Cold + Head Congestion Severe Medicine Caplets for Fever, Pain, and Congestion, Acetaminophen Pain Reliever, Fever Reducer, 24 Count

10% Off
Main highlights

Comprehensive Relief
24-count caplets relieve headache, congestion, sore throat, and fever.

Ideal for Cold and Flu
Best for adults and children 12+ with severe symptoms.

Customer Praised Clarity
Highly rated for keeping head clear and improving breathing.
8.7

Very Good

Our Rating

9.5
pain management

8.2
For teething

8.0
worth the money
9

Tylenol
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

27% Off
Main highlights

Comprehensive Cold Flu Relief
24-count pack offers multi-symptom relief for cold and flu.

Day Night Usage
Ideal for day and night relief with separate formulas.

Highly Praised Value
Customers appreciate the value and effectiveness of the product.
8.6

Very Good

Our Rating
10

Vicks
Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief
Main highlights

Maximum Strength 9-Symptom Relief
NyQuil SEVERE provides fast relief for 9 cold and flu symptoms, including cough, fever, and congestion.

Ideal for Nighttime Cold Relief
Designed to help you sleep by alleviating symptoms that keep you awake.

Praised for Effective Symptom Relief
Customers love NyQuil SEVERE for its reliable and quick symptom relief.
8.4

Good

Our Rating

9.3
worth the money

9.1
Flavor

10 Best otc cold medicines of 2025

1

Beekeeper's Naturals Kids Propolis Throat Spray 95% Bee Propolis Extract - Natural Immune Support & Sore Throat Relief, Antioxidants & Gluten-Free, 1.06 oz (Pack of 2)

9.7

9.3

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies

8.9

8.7

8.0

3

Boiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count

9.7

9.7

9.7

4

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

5

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

9.3

9.1

8.7

6

Mucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets

7

Zicam Cold Remedy Zinc Medicated Fruit Drops, Assorted Flavors, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count

9.5

9.1

8

Tylenol Cold + Head Congestion Severe Medicine Caplets for Fever, Pain, and Congestion, Acetaminophen Pain Reliever, Fever Reducer, 24 Count

9.5

8.2

8.0

9

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

10

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.3

9.1

Similar products on Amazon

Sudafed PE Sinus Pressure + Pain Relief Tablets, Maximum Strength, Non-Drowsy, OTC Sinus Relief Medicine with Acetaminophen Pain Reliever & Phenylephrine HCl Nasal Decongestant, 24 ct

$7.99

Tylenol Sinus Severe Daytime Cold & Flu Relief Medicine Caplets, Non-Drowsy Pain Reliever, Fever Reducer Expectorant & Decongestant, Acetaminophen, Guaifenesin & Phenylephrine HCl, 24 ct

$7.64

Sign up and get exclusive special deals