Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
Advertising Disclosure
10 Best otc cold medicines of 2025
Explore up to 41% off
- Best Choice
1
Clicked 4 times in the last monthBeekeeper's NaturalsBeekeeper's Naturals Kids Propolis Throat Spray 95% Bee Propolis Extract - Natural Immune Support & Sore Throat Relief, Antioxidants & Gluten-Free, 1.06 oz (Pack of 2)
- Curious about how we select the top products for you? Explore How It Works
- Value for Money
2
GenCareGenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies
41% Off 3
BoironBoiron Oscillococcinum For Relief From Flu-Like Symptoms Of Body Aches, Headache, Fever, Chills, And Fatigue - 30 Count
25% Off4
VicksVICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
15% Off5
Amazon Basic CareAmazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
33% Off-
See Today’s Deals & Prices
6
MucinexMucinex Sinus Max Severe Congestion & Pain Relief, Maximum Strength Nasal & Sinus Relief, Decongestant for Adults, Acetaminophen Pain Reliever, Guaifenesin Expectorant and Mucus Removal, 20 Caplets
21% Off7
ZicamZicam Cold Remedy Zinc Medicated Fruit Drops, Assorted Flavors, Homeopathic, Cold Shortening Medicine, Shortens Cold Duration, 25 Count
8
TylenolTylenol Cold + Head Congestion Severe Medicine Caplets for Fever, Pain, and Congestion, Acetaminophen Pain Reliever, Fever Reducer, 24 Count
10% Off9
TylenolTylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count
27% Off10
VicksVicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief