10 Best otc allergies of 2025

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Best Choice

1

Zyrtec
Zyrtec 24 Hour Allergy Relief Tablets, Fast-Acting Allergy Medicine for Indoor & Outdoor Allergies, Cetirizine 10 mg Tablet Antihistamine, 30 ct Bottle & 3 Single-Dose Travel Packs Bundle Pack
Main highlights

Powerful 24-Hour Relief
Provides all-day relief from indoor and outdoor allergy symptoms with a single dose.

Versatile Allergy Solution
Ideal for treating allergies caused by dust, mold, pet dander, pollen, weeds, and grasses.

Highly Praised Effectiveness
Customers appreciate its ability to stop itching and provide relief.
9.8

Exceptional

Our Rating
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Value for Money

2

Claritin
Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 30 Tablets + 1ct On-The-Go Relief

14% Off
Main highlights

Powerful 24-Hour Relief
Provides non-drowsy relief for indoor and outdoor allergies.

Ideal for Travelers
Includes 31 tablets, with one conveniently packaged for travel.

Praised for Small Size
Customers appreciate the compact bottle for easy storage and travel.
Key specs
- dosage:10mg per tablet
- form:Tablet
- active ingredient:Loratadine 10mg
- symptom relief:Sneezing, runny nose, itchy eyes
- pack size:31 days
9.6

Exceptional

Our Rating
3

Amazon Basic Care
Amazon Basic Care 24 Hour Allergy Relief, Cetirizine Hydrochloride Tablets, 10 mg, 300 Count (Packaging may vary)
Main highlights

24-Hour Allergy Relief
Provides relief from indoor and outdoor allergy symptoms for 24 hours.

Ideal for Budget-Conscious Users
Perfect for those seeking cost-effective allergy relief.

Comparable Effectiveness to Major Brands
Praised for matching the efficacy of Zyrtec and Allertec.
9.5

Excellent

Our Rating

9.9
simple to consume

9.3
worth the money

9.1
Flavor
4

ValuMeds
ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count)
Main highlights

24-Hour Allergy Relief
Experience effective, long-lasting relief from allergies with cetirizine hydrochloride.

Ideal for Busy Lifestyles
Non-drowsy formula perfect for work, school, or daily activities.

Highly Rated Value
Customers appreciate the quality and cost-effectiveness compared to brand names.
9.4

Excellent

Our Rating

9.9
simple to consume

9.3
worth the money

9.3
quality of ingredients
5

MAJOR
Major Allergy Loratadine 10 mg Tablets - Non-Drowsy Allergy Medicine for Adults and Kids Ages 6+ - Promotes 24-Hour Allergy Relief - Daily Allergy Tablets - Antihistamine - 300 Tablets
Main highlights

Large Quantity and Cost Efficiency
300 tablets provide a long-lasting supply, reducing frequent purchases and offering great value for money.

Ideal for Daily Allergy Relief
Perfect for individuals needing consistent allergy management without frequent re-purchasing.

Highly Praised for Affordability
Customers appreciate the significant cost savings compared to national brands.
9.3

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count
Main highlights

Powerful Allergy Relief
Contains diphenhydramine HCl 25 mg for effective multi-symptom relief.

Nighttime Use
Ideal for nighttime use to relieve allergies and aid sleep.

Highly Praised Sleep Aid
Customers appreciate its effectiveness as a sleep aid.
9.2

Excellent

Our Rating

9.9
simple to consume

9.7
worth the money

9.3
Flavor
7

Amazon Basic Care
Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, Antihistamine, 10 mg, 365 Count (Packaging may vary)
Main highlights

24-Hour Relief
Provides up to 24 hours of temporary relief from allergy symptoms.

Indoor and Outdoor Use
Effective for both indoor and outdoor allergy symptom relief.

Budget-Friendly Alternative
Praised for being a cost-effective alternative to Zyrtec and Allertec.
Key specs
- dosage:10 mg
- form:tablets
- active ingredient:cetirizine hydrochloride
- symptom relief:allergy symptoms
- pack size:N/A
9.1

Excellent

Our Rating
8

GenCare
GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

18% Off
Main highlights

24 Hour Non Drowsy Relief
Provides full-day relief from allergies without causing drowsiness.

Effective for Indoor and Outdoor Allergies
Ideal for hay fever, pollen, dust, pet dander, and seasonal allergies.

Comparable to Brand Name Effectiveness
Praised for being as effective as brand-name allergy medications.
Key specs
- dosage:10mg
- form:Tablets
- active ingredient:Cetirizine HCL
- symptom relief:Allergy, itching, congestion
- pack size:200 pills
9.0

Excellent

Our Rating

9.7
simple to consume

9.5
worth the money
9

HealthCareAisle
HealthCareAisle Allergy Relief - Fexofenadine Hydrochloride Tablets USP, 180 mg, 90 Tablets, Allergy Medication, Non-Drowsy 24-Hour Relief
Main highlights

Non-Drowsy Long-Lasting Relief
Fexofenadine provides 24-hour non-drowsy relief from indoor and outdoor allergies.

Ideal for Persistent Allergy Sufferers
Perfect for those needing consistent relief from hay fever and upper respiratory allergies.

Cost-Effective Alternative
Customers praise its effectiveness comparable to name brands at a lower cost.
8.9

Very Good

Our Rating
10

HealthA2Z
HealthA2Z Fexofenadine Hydrochloride 180mg, Antihistamine for Allergy Relief, 24-Hour Antihistamine for Allergy Relief (120 Count (Pack of 1))
Main highlights

Affordable Allergy Relief
HealthA2Z Fexofenadine offers cost-effective, non-drowsy allergy relief for 24 hours.

Ideal for Daily Use
Perfect for individuals seeking consistent allergy relief without frequent repurchasing.

Praised for Cost-Effectiveness
Customers appreciate the significant savings compared to branded alternatives.
8.7

Very Good

Our Rating

9.7
simple to consume

9.5
worth the money

10 Best otc allergies of 2025

1

Zyrtec 24 Hour Allergy Relief Tablets, Fast-Acting Allergy Medicine for Indoor & Outdoor Allergies, Cetirizine 10 mg Tablet Antihistamine, 30 ct Bottle & 3 Single-Dose Travel Packs Bundle Pack

How do we rank?

How do we rank?

Analyzing top stores

2

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 30 Tablets + 1ct On-The-Go Relief

3

Amazon Basic Care 24 Hour Allergy Relief, Cetirizine Hydrochloride Tablets, 10 mg, 300 Count (Packaging may vary)

9.9

9.3

9.1

4

ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count)

9.9

9.3

9.3

5

Major Allergy Loratadine 10 mg Tablets - Non-Drowsy Allergy Medicine for Adults and Kids Ages 6+ - Promotes 24-Hour Allergy Relief - Daily Allergy Tablets - Antihistamine - 300 Tablets

6

Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count

9.9

9.7

9.3

7

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, Antihistamine, 10 mg, 365 Count (Packaging may vary)

8

GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

9.7

9.5

9

HealthCareAisle Allergy Relief - Fexofenadine Hydrochloride Tablets USP, 180 mg, 90 Tablets, Allergy Medication, Non-Drowsy 24-Hour Relief

10

HealthA2Z Fexofenadine Hydrochloride 180mg, Antihistamine for Allergy Relief, 24-Hour Antihistamine for Allergy Relief (120 Count (Pack of 1))

9.7

9.5

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