Our rankings are generated through the algorithmic analysis of thousands of customer reviews about products, brands, merchant customer service levels, popularity trends, and more. We use advanced technology, including AI, to help process and organize this information at scale, supporting our analysis with greater speed and consistency. The rankings reflect our opinion and should be a good starting point for shopping.
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10 Best nyquil severe colds of 2026
Explore top picks
Best Choice1
Vicks9.8Exceptional
Vicks NyQuil SEVERE Cold & Flu Liquid Twin Pack, Nighttime Relief Medicine for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sneezing, Runny Nose, Cough, Berry Flavor, 2x12 OZ
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is discontinued by manufacturer:No
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product dimensions:5.25 x 2.75 x 6.85 inches 1.5 Pounds
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country of origin:USA
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asin:B00EQA35XE
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date first available:September 4, 2013
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Value for Money2
Vicks9.6Exceptional
Vicks NyQuil Severe Cold, Flu, & Congestion Medicine, 24 Liquicaps, Maximum Strength, 24Count
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is discontinued by manufacturer:N/A
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product dimensions:3.31 x 1.1 x 4.33 inches; 2.1 ounces
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country of origin:N/A
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asin:B07GXFHBJ8
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date first available:August 29, 2018
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3
Amazon Basic Care9.5Excellent
Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine for Cough, Sore Throat, Nasal Congestion, Pain Reliever, Fever Reducer, Original, 12 fl oz
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is discontinued by manufacturer:N/A
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product dimensions:2.5 x 2.5 x 7.25 inches; 15.52 ounces
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country of origin:N/A
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asin:B09HJTM8DK
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date first available:February 2, 2022
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4
Vicks9.3Excellent
Vicks NyQuil SEVERE Cold and Flu Relief Liquid Medicine, Maximum Strength, 9-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Runny Nose, Cough, 8 FL OZ
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is discontinued by manufacturer:No
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product dimensions:2.2 x 2.3 x 6.35 inches 8 ounces
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country of origin:USA
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asin:B01B1JQ87C
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date first available:January 28, 2016
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5
Amazon Basics9.1Excellent
Amazon Basics Nighttime Severe Cold and Flu Syrup, Max Strength, Multi-Symptom Relief for Adults and Children 12 Years and Older, Berry Flavor, 12 fl oz (Previously Care)
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is discontinued by manufacturer:N/A
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product dimensions:2.5 x 2.5 x 7.25 inches 0.04 ounces
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country of origin:USA
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asin:B00ASEO13A
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date first available:June 23, 2013
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6
Vicks9.0Excellent
Vicks DayQuil & NyQuil Severe Cold & Flu LiquiCap Medicine, 48ct
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7
Vicks8.9Very Good
Vicks DayQuil & NyQuil SEVERE Cold & Flu Medicine, Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Nasal Congestion, Sinus Pressure, Stuffy Nose, and Cough, Co-Pack, 2 x 12 OZ
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is discontinued by manufacturer:No
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product dimensions:2.8 x 5.38 x 6.96 inches; 7.84 ounces
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country of origin:N/A
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asin:B00EQA34W6
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date first available:September 16, 2013
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8
Amazon Basic Care8.7Very Good
Amazon Basic Care Nighttime Severe Cold and Flu Relief Caplets, Vapor Ice, 24 Count
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is discontinued by manufacturer:N/A
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product dimensions:1 x 4.38 x 3.25 inches 1.13 ounces
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country of origin:USA
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asin:B087D3FHG1
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date first available:April 1, 2021
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9
Vicks8.4Good
NyQuil Ultra Concentrated Cold and Flu Medicine, Nighttime, Relief for Cough, Sore Throat, Fever, Congestion, Easy to Swallow, Easy to Open Bottle, 48 LiquiCaps
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10
Vicks8.2Good
Vicks DayQuil and NyQuil Severe Cold & Flu, Honey, Liquid Over-the-Counter Medicine, 2x12 Oz
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is discontinued by manufacturer:N/A
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product dimensions:5.47 x 2.21 x 7.4 inches 1.68 Pounds
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country of origin:Canada
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asin:B08BPZVLC9
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date first available:July 7, 2020
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