10 Best nyquil severe colds of 2026

Save up to 18% off

Best Choice

1

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.7

Exceptional

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Vicks
Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief
Main highlights

Maximum Strength 9-Symptom Relief
NyQuil SEVERE provides fast relief for 9 cold and flu symptoms, including cough, fever, and congestion.

Ideal for Nighttime Cold Relief
Designed to help you sleep by alleviating symptoms that keep you awake.

Praised for Effective Symptom Relief
Customers love NyQuil SEVERE for its reliable and quick symptom relief.
9.5

Excellent

Our Rating

9.3
worth the money

9.1
Flavor
3

Vicks
Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief
Main highlights

Maximum Strength 9-Symptom Relief
NyQuil SEVERE provides fast relief for 9 cold and flu symptoms, including cough, fever, and congestion.

Ideal for Nighttime Cold Relief
Designed to help you sleep by alleviating symptoms that keep you awake.

Praised for Effective Symptom Relief
Customers love NyQuil SEVERE for its reliable and quick symptom relief.
9.3

Excellent

Our Rating

9.3
worth the money

9.1
Flavor
4

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.1

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
5

Vicks
Vicks NyQuil Severe Cold, Flu, & Congestion Medicine, 24 Liquicaps, Maximum Strength, 24Count
Main highlights

Comprehensive Symptom Relief
Provides maximum strength relief for cough, headache, fever, sore throat, aches, nasal congestion, and more.

Ideal for Severe Cold and Flu
Best suited for tackling severe cold, flu, and congestion symptoms effectively.

Highly Effective for Symptom Management
Customers frequently praise its effectiveness in alleviating multiple symptoms quickly.
8.9

Very Good

Our Rating
See Today’s Deals & Prices
6

Amazon Basic Care
Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

10% Off
Main highlights

Maximum Strength Relief
Provides comprehensive relief for headache, fever, sore throat, sinus congestion, and cough with maximum strength ingredients.

Nighttime Use for Restful Sleep
Ideal for nighttime use to ensure restful sleep while managing severe cold and flu symptoms.

Effective Sleep Aid
Frequently praised for its quick and effective sleep-inducing properties, helping users rest better.
Key specs
- form:liquid
- symptom relief:cold and flu
- flavor:mixed berry
- active ingredient:acetaminophen 650 mg
- dosage:N/A
8.8

Very Good

Our Rating

9.1
worth the money

8.7
Comfort

8.2
Flavor
7

Amazon Basic Care
Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

15% Off
Main highlights

Maximum Strength Relief
Provides comprehensive relief for headache, fever, sore throat, sinus congestion, and cough with maximum strength ingredients.

Nighttime Use for Restful Sleep
Ideal for nighttime use to ensure restful sleep while managing severe cold and flu symptoms.

Effective Sleep Aid
Frequently praised for its quick and effective sleep-inducing properties, helping users rest better.
Key specs
- form:liquid
- symptom relief:cold and flu
- flavor:mixed berry
- active ingredient:acetaminophen 650 mg
- dosage:N/A
8.7

Very Good

Our Rating

9.1
worth the money

8.7
Comfort

8.2
Flavor
8

Amazon Basic Care
Amazon Basic Care Nighttime Severe Cold & Flu Liquid, Original, 12 fl oz (Pack of 1)

14% Off
Main highlights

Key Features and Benefits
Maximum strength formula with pain reliever, cough suppressant, antihistamine, and nasal decongestant; sugar and gluten-free.

Ideal Use Cases
Best for nighttime use, providing relief from severe cold and flu symptoms, aiding in restful sleep.

Customer Reviews Summary
Highly praised for effectively soothing severe symptoms and improving sleep quality during illness.
8.5

Good

Our Rating

9.1
worth the money

8.7
Comfort

8.2
Flavor
9

Amazon Basic Care
Amazon Basic Care Nighttime Severe Cold & Flu Liquid, Original, 12 fl oz (Pack of 1)

18% Off
Main highlights

Key Features and Benefits
Maximum strength formula with pain reliever, cough suppressant, antihistamine, and nasal decongestant; sugar and gluten-free.

Ideal Use Cases
Best for nighttime use, providing relief from severe cold and flu symptoms, aiding in restful sleep.

Customer Reviews Summary
Highly praised for effectively soothing severe symptoms and improving sleep quality during illness.
8.3

Good

Our Rating

9.1
worth the money

8.7
Comfort

8.2
Flavor
10

Vicks
Vicks NyQuil SEVERE Cold and Flu Relief Liquid Medicine, Maximum Strength, 9-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Runny Nose, Cough, 8 FL OZ
Main highlights

Powerful 9-Symptom Relief
NyQuil SEVERE offers maximum strength relief for 9 cold and flu symptoms, including headache, fever, and sore throat.

Ideal Nighttime Use
Best used at night for fast relief, allowing uninterrupted sleep despite cold or flu symptoms.

Customer Praised Fast Relief
Customers frequently praise its rapid onset, providing effective relief to help manage severe cold and flu symptoms.
Key specs
- form:Liquid
- symptom relief:Cold & flu symptoms
- flavor:N/A
- active ingredient:N/A
- dosage:One dose
8.1

Good

Our Rating

10 Best nyquil severe colds of 2026

1

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

How do we rank?

How do we rank?

Analyzing top stores

2

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.3

9.1

3

Vicks NyQuil SEVERE Cold, Flu, and Congestion Medicine, 2x12 fl oz Twin Pack, Berry Flavor, Maximum Strength, Nighttime Relief

9.3

9.1

4

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

5

Vicks NyQuil Severe Cold, Flu, & Congestion Medicine, 24 Liquicaps, Maximum Strength, 24Count

6

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

9.1

8.7

8.2

7

Amazon Basic Care Nighttime Severe Cold and Flu Syrup, Max Strength Liquid Medicine, Multi-Symptom Relief, for Adults and Children 12 Years and Older, Mixed Berry Flavor, 12 fl oz (Pack of 1)

9.1

8.7

8.2

8

Amazon Basic Care Nighttime Severe Cold & Flu Liquid, Original, 12 fl oz (Pack of 1)

9.1

8.7

8.2

9

Amazon Basic Care Nighttime Severe Cold & Flu Liquid, Original, 12 fl oz (Pack of 1)

9.1

8.7

8.2

10

Vicks NyQuil SEVERE Cold and Flu Relief Liquid Medicine, Maximum Strength, 9-Symptom Nighttime Relief For Headache, Fever, Sore Throat, Nasal Congestion, Sinus Pressure, Runny Nose, Cough, 8 FL OZ

Sign up and get exclusive special deals