10 Best numbing gels of 2025

Explore top picks

Best Choice

1

Secondary Numb

Secondary Numb Microblading Numbing Gel REDNESS STOPPING | Fast Acting Numbing Cream for Permanent Makeup Procedures | Ultra Duration Pain Relief Gel with 5% Lidocaine (1.1 Ounce)
9.7

Exceptional

Our Rating
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Value for Money

2

tuiwaro

Painless Tattoo Numbing Cream for Tattoos Extra Strength, Tattoo Numbing Cream Maximum Strength for Waxing & Piercing
9.4

Excellent

Our Rating
3

Ebanel
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
Main highlights

Fast-Acting Long-Lasting Relief
Ebanel 5 Lidocaine Cream provides quick, enduring numbing for pain relief and itch reduction.

Ideal for Skin Procedures
Perfect for tattoos, microneedling, waxing, and injections, enhancing comfort during sessions.

Highly Praised Numbing Effect
Customers commend its ability to significantly reduce discomfort and improve treatment experience.
9.3

Excellent

Our Rating

8.9
Simple to use

8.0
Absorbency

8.0
Gentle
4

WELMATE

WELMATE - 5% Lidocaine Numbing Cream, 1oz (30g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care, HSA & FSA Eligible
9.2

Excellent

Our Rating
5

HealthWise
HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz
Main highlights

Maximum Strength Relief
Provides temporary relief of minor aches and pains associated with arthritis, strains, and bruises.

Ideal for Minor Aches
Perfect for use on bruises, mild joint pain, and simple backaches.

Praised for Fast Numbing
Customers appreciate the quick numbing effect and excellent value.
Key specs
- Package Type:1.75 oz. bottle
- Active Ingredients:Lidocaine 4%
- Application Method:Apply directly to skin
- Effect Duration:6-8 hours
- Formulation:Non-greasy cream
9.1

Excellent

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
worth the money
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6

Treatonic

5% Lidocaine Numbing Cream: Lidocaine Cream Maximum Strength for Pain Relief, Itching, Burning, Soreness, Hemorrhoid - Fast Acting & Long Lasting Numbing Cream- 2.1 oz
9.0

Excellent

Our Rating
7

XESSO
XESSO Water-Based Anal Comfort Lube for Men Women Couples 8.3 Fl Oz, Gently Numbing, Backdoor Relax Desensitizing Gel, Rear Comfort Lube Made in US, Discreet Packaging
Main highlights

Quick Pain Relief
Contains a fast-acting numbing agent for pain reduction.

Ideal for Anal Use
pH-balanced and jellylike consistency for comfortable anal application.

Effective Numbing
Customers praise its effective numbing without affecting partner.
Key specs
- Size:1.86 x 1.86 x 7.38 inches
- Ingredients:Numbing agent, pH-balanced
- Purpose:Ease pain, soreness, burning
- Scent:Unscented
- Compatibility:Anal use
8.9

Very Good

Our Rating

8.9
Comfort

8.4
Simple to clean

8.2
worth the money
8

EBANEL LABORATORIES
Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses
Main highlights

Fast-Acting Pain Relief
Ebanel 5 Lidocaine Spray offers immediate relief from pain, itching, and discomfort with its enhanced lidocaine and phenylephrine formula.

Versatile Use Cases
Ideal for tattoos, waxing, and minor skin irritations, providing temporary relief and comfort in sensitive areas.

Effective Numbing Experience
Customers praise its ability to significantly reduce pain during long tattoo sessions and other procedures.
Key specs
- active ingredients:Lidocaine, Phenylephrine HCl
- application method:Spray on skin
- usage:Numbing, itch relief
- formulation:Spray
- pain relief:Immediate, 1 hour duration
8.6

Very Good

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
pain management
9

Curist
Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)
Main highlights

Maximum Strength Relief
Experience deep pain relief with 5% lidocaine, the strongest OTC formulation.

Versatile Use Cases
Ideal for hemorrhoids, bug bites, rashes, bruises, and more.

Highly Recommended Application
Customers praise its non-greasy, quick-absorbing formula and long-lasting effect.
8.5

Good

Our Rating

8.2
pain management

8.0
worth the money
10

Orajel
Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief
Main highlights

Instant Pain Relief with Maximum Strength Formula
Orajel provides immediate pain relief for tooth and gum discomfort with its maximum strength formula containing 20% benzocaine.

Emergency Dental Pain Relief
Ideal for providing temporary relief from toothaches, gum irritation, and pain from dental aligners, helping avoid emergency dental visits.

Fast-Acting and Effective
Customers frequently praise Orajel for its quick pain relief and effectiveness, although some mention the need for frequent reapplication and issues with the tube design.
Key specs
- Active Ingredients:20% benzocaine
- Application Method:Ready-Open Tube Tip
- Formulation:Gel
- Target Area:Tooth and gums
- Age Suitability:Adults
8.3

Good

Our Rating

9.5
pain management

9.1
Long life

8.7
Simple to use

10 Best numbing gels of 2025

1

Secondary Numb Microblading Numbing Gel REDNESS STOPPING | Fast Acting Numbing Cream for Permanent Makeup Procedures | Ultra Duration Pain Relief Gel with 5% Lidocaine (1.1 Ounce)

How do we rank?

How do we rank?

Analyzing top stores

2

Painless Tattoo Numbing Cream for Tattoos Extra Strength, Tattoo Numbing Cream Maximum Strength for Waxing & Piercing

3

Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

8.9

8.0

8.0

4

WELMATE - 5% Lidocaine Numbing Cream, 1oz (30g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care, HSA & FSA Eligible

5

HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz

8.2

8.0

8.0

6

5% Lidocaine Numbing Cream: Lidocaine Cream Maximum Strength for Pain Relief, Itching, Burning, Soreness, Hemorrhoid - Fast Acting & Long Lasting Numbing Cream- 2.1 oz

7

XESSO Water-Based Anal Comfort Lube for Men Women Couples 8.3 Fl Oz, Gently Numbing, Backdoor Relax Desensitizing Gel, Rear Comfort Lube Made in US, Discreet Packaging

8.9

8.4

8.2

8

Ebanel 5% Lidocaine Spray Pain Relief Numb520 Burn Itch Relief Numbing Spray for Skin, Topical Anesthetic Postpartum Hemorrhoid Treatment with Phenylephrine for Local and Anorectal Uses

8.0

8.0

8.0

9

Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)

8.2

8.0

10

Orajel 3X for Toothache & Gum Pain: Maximum Gel Tube 0.42oz - From #1 Oral Pain Relief Brand - Orajel for Instant Pain Relief

9.5

9.1

8.7

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