10 Best nerve pain relief creams of 2025

Save up to 32% off

Best Choice

1

Pharmapulse
Pharmapulse Neuropathy Nerve Relief Cream – Maximum Strength for Feet, Hands, Legs, Toes, Lower Back - Alpha Lipoic Acid, Arnica, Vitamin B6, Aloe Vera, MSM - Effective Soothing
Main highlights

Concentrated Blend for Relief
Includes Alpha Lipoic Acid, Arnica, Vitamin B6 for targeted discomfort relief.

Ideal for Neuropathy and Joint Pain
Designed for feet, hands, legs, toes, and lower back discomfort.

Effective and Pleasant Scent
Customers praise its effectiveness and subtle scent compared to other creams.
9.8

Exceptional

Our Rating

9.9
Simple to use

9.1
worth the money

8.7
Aroma
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

HUSPUR

HUSPUR Neuropathy Cream, Magnesium Cream for Neuropathy, Nerve Relief Lotion for Feet Hand Nerve Neuropathy No Greasy Body Lotion Cream with Natrural Ingredients For Soothing Body Day Night, Lavender

11% Off
9.7

Exceptional

Our Rating
3

Lindesa

Neuropathy Pain Relief Cream, Nerve Pain Relief Cream,Fast Acting Maximum Strength for Feet, Hands, Legs, Muscles, Joints, Waist Includes Arnica, Vitamin B6, Aloe Vera, MSM -Mild & All Natural

32% Off
9.6

Exceptional

Our Rating
4

Nervive
Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz
Main highlights

Powerful Pain Relief
Contains Lidocaine and Menthol for maximum strength relief from nerve pain.

Comprehensive Nerve Care
Ideal for relieving pain in toes, feet, fingers, hands, legs, and arms.

Fast Acting Formula
Customers praise its quick action, working in less than 5 minutes.
9.4

Excellent

Our Rating

8.0
worth the money

8.0
pain management
5

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

30% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
Key specs
- Package Type:Bottle
- Active Ingredients:4% Lidocaine
- Application Method:Topical
- Effect Duration:Hours
- Formulation:Cream
9.1

Excellent

Our Rating

8.4
worth the money

8.4
pain management
See Today’s Deals & Prices
6

OWELL NATURALS
OWELL NATURALS Neuropathy Cream Extra Strength Nerve Relief Cream for Foot, Hands, Legs, Toes with Arnica, Vitamin B6, Aloe Vera, MSM - Made in USA
Main highlights

Effective Neuropathy Relief
OWELL NATURALS Neuropathy Cream offers targeted relief for neuropathy pain with Arnica, Vitamin B6, Aloe Vera, and MSM.

Ideal for Muscle and Nerve Pain
Perfect for neuropathy, muscle soreness, arthritis, and pulled muscles, providing comfort and easing discomfort.

Highly Praised for Pain Relief
Customers frequently commend its effectiveness in reducing pain and its pleasant scent.
Key specs
- Type:Neuropathy Pain Relief
- Effectiveness:Effective neuropathy pain relief
- Formulation:Cream
- Ingredients:Arnica, Vitamin B6, Aloe Vera, MSM
- Safety:Cruelty-free, non-GMO, chemical-free
9.0

Excellent

Our Rating

9.3
pain management

8.7
Absorbency

8.0
Aroma
7

Nervive
Nervive Pain Relieving Roll On Liquid, Max Strength No-Mess Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 2.5oz
Main highlights

Maximum Strength Relief
Formulated with Lidocaine HCL 4% and Menthol 1% for effective pain relief.

Ideal for Nerve Pain
Targets multiple nerve pain receptors in toes, feet, fingers, hands, legs, and arms.

Fast Acting Relief
Starts working in less than 5 minutes, praised for quick effectiveness.
8.7

Very Good

Our Rating

8.4
Simple to use

8.0
worth the money

8.0
pain management
8

Hempvana
Hempvana Ultra-Strength Nerve Relief Cream w/100% Pure Hemp Seed Oil, AS-SEEN-ON-TV, Relieves Nerve Pain, Shooting Pain, Joint Pain, Tingling, Muscle Cramps, Crawling Sensations, 3 oz Jar
Main highlights

Ultra-Strength Pain Relief
Formulated with pure hemp seed oil and homeopathic ingredients for fast, ultra-strength pain relief.

Ideal for Nerve Discomfort
Best used for targeting nerve and muscular discomfort with quick absorption and non-greasy formula.

Praised for Quick Absorption
Customers appreciate its quick absorption and non-greasy feel, providing lasting relief.
Key specs
- Type:Topical pain relief
- Effectiveness:Temporarily relieves pain
- Formulation:Ultra-strength, Non-greasy
- Ingredients:Pure hemp seed oil, Arnica
- Safety:Made in America
8.5

Good

Our Rating
9

WHWSWB

WHWSWB Neuropathy Nerve Relief Cream - Maximum Strength for Feet, Hands, Legs, Toes Includes Menthol, Arnica, Aloe Vera, Emu, MSM, Vitamin B6, Effective Cooling Soothing

15% Off
8.3

Good

Our Rating
10

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
8.0

Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients

10 Best nerve pain relief creams of 2025

1

Pharmapulse Neuropathy Nerve Relief Cream – Maximum Strength for Feet, Hands, Legs, Toes, Lower Back - Alpha Lipoic Acid, Arnica, Vitamin B6, Aloe Vera, MSM - Effective Soothing

9.9

9.1

8.7

How do we rank?

How do we rank?

Analyzing top stores

2

HUSPUR Neuropathy Cream, Magnesium Cream for Neuropathy, Nerve Relief Lotion for Feet Hand Nerve Neuropathy No Greasy Body Lotion Cream with Natrural Ingredients For Soothing Body Day Night, Lavender

3

Neuropathy Pain Relief Cream, Nerve Pain Relief Cream,Fast Acting Maximum Strength for Feet, Hands, Legs, Muscles, Joints, Waist Includes Arnica, Vitamin B6, Aloe Vera, MSM -Mild & All Natural

4

Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz

8.0

8.0

5

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

6

OWELL NATURALS Neuropathy Cream Extra Strength Nerve Relief Cream for Foot, Hands, Legs, Toes with Arnica, Vitamin B6, Aloe Vera, MSM - Made in USA

9.3

8.7

8.0

7

Nervive Pain Relieving Roll On Liquid, Max Strength No-Mess Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 2.5oz

8.4

8.0

8.0

8

Hempvana Ultra-Strength Nerve Relief Cream w/100% Pure Hemp Seed Oil, AS-SEEN-ON-TV, Relieves Nerve Pain, Shooting Pain, Joint Pain, Tingling, Muscle Cramps, Crawling Sensations, 3 oz Jar

9

WHWSWB Neuropathy Nerve Relief Cream - Maximum Strength for Feet, Hands, Legs, Toes Includes Menthol, Arnica, Aloe Vera, Emu, MSM, Vitamin B6, Effective Cooling Soothing

10

Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

Sign up and get exclusive special deals