10 Best nerve pain creams of 2025

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Raitera
Raitera Neuropathy Relief Cream - 7 oz - Maximum Strength Nerve Relief for Feet Hands Legs Toes - Natural Ingredients Frankincense Arnica Aloe Vera Emu MSM Hemp - Fast-Acting Formula
Main highlights

Fast Acting Nerve Relief
Experience maximum strength relief from discomfort in minutes with our neuropathy cream.

Ideal for Multiple Body Areas
Perfect for feet, hands, legs, and neck to relieve discomfort.

Substantial Cream Texture
Praised for its effectiveness and substantial texture compared to competitors.
Key specs
- Type:Neuropathy relief
- Effectiveness:Fast-acting, improves circulation
- Formulation:Cream
- Ingredients:MSM, arnica, menthol, eucalyptus
- Safety:Doctor formulated, tested
9.8

Exceptional

Our Rating
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Value for Money

2

Pharmapulse
Pharmapulse Neuropathy Nerve Relief Cream – Maximum Strength for Feet, Hands, Legs, Toes, Lower Back - Alpha Lipoic Acid, Arnica, Vitamin B6, Aloe Vera, MSM - Effective Soothing
Main highlights

Concentrated Blend for Relief
Includes Alpha Lipoic Acid, Arnica, Vitamin B6 for targeted discomfort relief.

Ideal for Neuropathy and Joint Pain
Designed for feet, hands, legs, toes, and lower back discomfort.

Effective and Pleasant Scent
Customers praise its effectiveness and subtle scent compared to other creams.
9.6

Exceptional

Our Rating

9.9
Simple to use

9.1
worth the money

8.7
Aroma
3

Lindesa

Neuropathy Pain Relief Cream, Nerve Pain Relief Cream,Fast Acting Maximum Strength for Feet, Hands, Legs, Muscles, Joints, Waist Includes Arnica, Vitamin B6, Aloe Vera, MSM -Mild & All Natural
9.5

Excellent

Our Rating
4

Nervive
Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz
Main highlights

Powerful Pain Relief
Contains Lidocaine and Menthol for maximum strength relief from nerve pain.

Comprehensive Nerve Care
Ideal for relieving pain in toes, feet, fingers, hands, legs, and arms.

Fast Acting Formula
Customers praise its quick action, working in less than 5 minutes.
9.3

Excellent

Our Rating

8.0
worth the money

8.0
pain management
5

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

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Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
Key specs
- Package Type:Bottle
- Active Ingredients:4% Lidocaine
- Application Method:Topical
- Effect Duration:Hours
- Formulation:Cream
9.0

Excellent

Our Rating

8.4
worth the money

8.4
pain management
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6

Penetrex
Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream
Main highlights

Deep Penetration Relief
Penetrex uses arnica, vitamin B6, and MSM for deep joint relief.

Versatile Application Areas
Perfect for back, neck, hands, feet, and more.

Healing Over Pain Relief
Customers praise its healing properties over mere pain relief.
8.7

Very Good

Our Rating

9.7
Simple to use

9.3
lasts a long time

9.3
quality of ingredients
7

OWELL NATURALS
OWELL NATURALS Neuropathy Cream Extra Strength Nerve Relief Cream for Foot, Hands, Legs, Toes with Arnica, Vitamin B6, Aloe Vera, MSM - Made in USA
Main highlights

Effective Neuropathy Relief
OWELL NATURALS Neuropathy Cream offers targeted relief for neuropathy pain with Arnica, Vitamin B6, Aloe Vera, and MSM.

Ideal for Muscle and Nerve Pain
Perfect for neuropathy, muscle soreness, arthritis, and pulled muscles, providing comfort and easing discomfort.

Highly Praised for Pain Relief
Customers frequently commend its effectiveness in reducing pain and its pleasant scent.
Key specs
- Type:Neuropathy Pain Relief
- Effectiveness:Effective neuropathy pain relief
- Formulation:Cream
- Ingredients:Arnica, Vitamin B6, Aloe Vera, MSM
- Safety:Cruelty-free, non-GMO, chemical-free
8.6

Very Good

Our Rating

9.3
pain management

8.7
Absorbency

8.0
Aroma
8

EpixCare

EpixCare Magnesium Cream for Neuropathy Nighttime Relaxation - Nerve Muscle Cramps & Body Pain Support Lotion with Lavender - Relaxing Calming Nighttime Rub for Feet Back Leg Circulation (4 oz)
8.4

Good

Our Rating
9

Nervive
Nervive Pain Relieving Roll On Liquid, Max Strength No-Mess Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 2.5oz
Main highlights

Maximum Strength Relief
Formulated with Lidocaine HCL 4% and Menthol 1% for effective pain relief.

Ideal for Nerve Pain
Targets multiple nerve pain receptors in toes, feet, fingers, hands, legs, and arms.

Fast Acting Relief
Starts working in less than 5 minutes, praised for quick effectiveness.
8.1

Good

Our Rating

8.4
Simple to use

8.0
worth the money

8.0
pain management
10

Hempvana
Hempvana Ultra-Strength Nerve Relief Cream w/100% Pure Hemp Seed Oil, AS-SEEN-ON-TV, Relieves Nerve Pain, Shooting Pain, Joint Pain, Tingling, Muscle Cramps, Crawling Sensations, 3 oz Jar
Main highlights

Ultra-Strength Pain Relief
Formulated with pure hemp seed oil and homeopathic ingredients for fast, ultra-strength pain relief.

Ideal for Nerve Discomfort
Best used for targeting nerve and muscular discomfort with quick absorption and non-greasy formula.

Praised for Quick Absorption
Customers appreciate its quick absorption and non-greasy feel, providing lasting relief.
Key specs
- Type:Topical pain relief
- Effectiveness:Temporarily relieves pain
- Formulation:Ultra-strength, Non-greasy
- Ingredients:Pure hemp seed oil, Arnica
- Safety:Made in America
7.9

Good

Our Rating

10 Best nerve pain creams of 2025

1

Raitera Neuropathy Relief Cream - 7 oz - Maximum Strength Nerve Relief for Feet Hands Legs Toes - Natural Ingredients Frankincense Arnica Aloe Vera Emu MSM Hemp - Fast-Acting Formula

How do we rank?

How do we rank?

Analyzing top stores

2

Pharmapulse Neuropathy Nerve Relief Cream – Maximum Strength for Feet, Hands, Legs, Toes, Lower Back - Alpha Lipoic Acid, Arnica, Vitamin B6, Aloe Vera, MSM - Effective Soothing

9.9

9.1

8.7

3

Neuropathy Pain Relief Cream, Nerve Pain Relief Cream,Fast Acting Maximum Strength for Feet, Hands, Legs, Muscles, Joints, Waist Includes Arnica, Vitamin B6, Aloe Vera, MSM -Mild & All Natural

4

Nervive Pain Relieving Cream, Max Strength Non-Greasy Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 3.0oz

8.0

8.0

5

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

6

Penetrex Joint & Muscle Therapy - Soothing Muscle Rub for Back, Neck, Hands, Feet - Premium Whole Body Rub with Arnica, Vitamin B6 MSM & Boswellia - Non-Greasy 2oz Cream

9.7

9.3

9.3

7

OWELL NATURALS Neuropathy Cream Extra Strength Nerve Relief Cream for Foot, Hands, Legs, Toes with Arnica, Vitamin B6, Aloe Vera, MSM - Made in USA

9.3

8.7

8.0

8

EpixCare Magnesium Cream for Neuropathy Nighttime Relaxation - Nerve Muscle Cramps & Body Pain Support Lotion with Lavender - Relaxing Calming Nighttime Rub for Feet Back Leg Circulation (4 oz)

9

Nervive Pain Relieving Roll On Liquid, Max Strength No-Mess Topical Pain Reliever with Lidocaine and Menthol for Toes, Feet, Fingers, Hands, Legs & Arms, 2.5oz

8.4

8.0

8.0

10

Hempvana Ultra-Strength Nerve Relief Cream w/100% Pure Hemp Seed Oil, AS-SEEN-ON-TV, Relieves Nerve Pain, Shooting Pain, Joint Pain, Tingling, Muscle Cramps, Crawling Sensations, 3 oz Jar

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