9 Best nasal spray for sinusitis of 2025

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Best Choice

1

Flonase
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief 144 Sprays, Bonus Pack of Tissues
Main highlights

24-Hour Non-Drowsy Relief
Flonase provides 24-hour non-drowsy relief for nasal congestion, runny nose, and itchy eyes.

Year-Round Allergy Protection
Ideal for indoor and outdoor allergies, including pollen, mold, and pet dander.

Highly Effective Performance
Customers praise its effectiveness despite occasional spray clogging issues.
9.6

Exceptional

Our Rating

9.3
Gentle

9.1
worth the money
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Value for Money

2

Nasacort
Nasacort 24HR Allergy Nasal Spray for Adults, Non-drowsy & Alcohol Free, 240 Sprays, 0.57 fl.oz. 2Ct

25% Off
Main highlights

24-Hour Relief
Nasacort provides a full 24 hours of relief from nasal allergy symptoms.

Ideal for Daily Use
Perfect for adults needing non-drowsy, long-lasting allergy relief.

Ease of Use
Praised for its easy application and effectiveness by users.
9.4

Excellent

Our Rating

8.7
Flavor

8.4
Simple to use

8.0
worth the money
3

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.2

Excellent

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
4

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
9.1

Excellent

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
5

Mucinex
Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce
Main highlights

Fast Acting Relief
Mucinex Sinus-Max provides quick relief from nasal and sinus congestion.

Ideal for Allergies
Perfect for allergy season, offering targeted congestion relief.

Customer Praised Effectiveness
Users love its fast action and long-lasting congestion relief.
8.9

Very Good

Our Rating
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6

Seagate
Seagate Products Homeopathic Olive Leaf Nasal Spray (Pack of 1) 1 Ounce
Main highlights

Safe and Natural Relief
Homeopathic formula with pure, chemical-free ingredients for sinus irritation relief.

Ideal for Chronic Sinus Issues
Designed for those with persistent sinus problems seeking natural alternatives.

Non-Habit Forming Benefit
Praised for being non-addictive and free from side effects.
8.8

Very Good

Our Rating

9.9
quality of ingredients

9.5
worth the money

9.3
Simple to use
7

Beekeeper's Naturals
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
Main highlights

Natural Ingredients and Benefits
Formulated with sea salt, propolis, and xylitol for sinus relief.

Ideal for Sinus Congestion
Perfect for relieving congestion caused by pollutants and allergens.

Customer Praised Natural Formula
Highly rated for its natural, chemical-free composition.
Key specs
- effects:Decongestant, reduces swelling
- safety:Non-GMO, non-addictive
- usage:Shake well, spray twice
- formulation:Saline solution, sea salt
- dimensions:1.37 x 1.37 x 5 inches
8.6

Very Good

Our Rating
8

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- active ingredients:oxymetazoline hydrochloride 0.05%
- decongestant:Yes
- saline solution:N/A
8.5

Good

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
9

NEO-SYNEPHRINE
Neosynephrine, Nasal Spray for Cold Sinus Relief Extra Strength, Clear, 0.5 Fl Oz

40% Off
Main highlights

Fast Acting Relief
Neosynephrine Extra Strength Nasal Spray provides quick relief from sinus congestion, helping you breathe easier within minutes.

Ideal for Sinus Congestion
Perfect for those suffering from cold-induced sinus congestion, offering up to four hours of relief.

Highly Praised Effectiveness
Customers consistently praise its ability to open sinus passages effectively, making it a trusted choice.
8.4

Good

Our Rating

9 Best nasal spray for sinusitis of 2025

1

Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief 144 Sprays, Bonus Pack of Tissues

9.3

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Nasacort 24HR Allergy Nasal Spray for Adults, Non-drowsy & Alcohol Free, 240 Sprays, 0.57 fl.oz. 2Ct

8.7

8.4

8.0

3

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

4

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

5

Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce

6

Seagate Products Homeopathic Olive Leaf Nasal Spray (Pack of 1) 1 Ounce

9.9

9.5

9.3

7

Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

8

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

9

Neosynephrine, Nasal Spray for Cold Sinus Relief Extra Strength, Clear, 0.5 Fl Oz

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