10 Best nasal spray for sinusitis of 2026

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1

Vicks
Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.7

Exceptional

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
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2

Beekeeper's Naturals
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
Main highlights

Natural Ingredients and Benefits
Formulated with sea salt, propolis, and xylitol for sinus relief.

Ideal for Sinus Congestion
Perfect for relieving congestion caused by pollutants and allergens.

Customer Praised Natural Formula
Highly rated for its natural, chemical-free composition.
Key specs
- effects:Decongestant, reduces swelling
- safety:Non-GMO, non-addictive
- usage:Shake well, spray twice
- formulation:Saline solution, sea salt
- dimensions:1.37 x 1.37 x 5 inches
9.5

Excellent

Our Rating
3

Beekeeper's Naturals
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

10% Off
Main highlights

Natural Ingredients and Benefits
Formulated with sea salt, propolis, and xylitol for sinus relief.

Ideal for Sinus Congestion
Perfect for relieving congestion caused by pollutants and allergens.

Customer Praised Natural Formula
Highly rated for its natural, chemical-free composition.
Key specs
- effects:Decongestant, reduces swelling
- safety:Non-GMO, non-addictive
- usage:Shake well, spray twice
- formulation:Saline solution, sea salt
- dimensions:1.37 x 1.37 x 5 inches
9.3

Excellent

Our Rating
4

Vicks
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

28% Off
Main highlights

Instant Sinus Relief
Clears stuffy nose in seconds, works 6x faster than tablets.

Ideal for Cold and Allergy
Effective for congestion and sinus pressure relief day or night.

Praised Metered Mist
Fine mist prevents dripping, ensuring easy and mess-free use.
Key specs
- features:Instant sinus relief
- product dimensions:5.08 x 2.76 x 2.13 inches
- decongestant:Nasal Spray
- active ingredients:N/A
- saline solution:N/A
9.2

Excellent

Our Rating
5

Vicks
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

32% Off
Main highlights

Instant Sinus Relief
Clears stuffy nose in seconds, works 6x faster than tablets.

Ideal for Cold and Allergy
Effective for congestion and sinus pressure relief day or night.

Praised Metered Mist
Fine mist prevents dripping, ensuring easy and mess-free use.
Key specs
- features:Instant sinus relief
- product dimensions:5.08 x 2.76 x 2.13 inches
- decongestant:Nasal Spray
- active ingredients:N/A
- saline solution:N/A
9.1

Excellent

Our Rating
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6

Xlear
Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)
Main highlights

Natural Decongestant and Moisturizer
Xlear Nasal Spray gently cleans, moisturizes, and decongests sinuses naturally with xylitol.

Ideal for Chronic Sinus Issues
Perfect for individuals with recurring sinus infections and allergies.

Highly Effective for Sinus Relief
Users praise its immediate relief from congestion and improved breathing.
Key specs
- features:Natural, safe for kids
- product dimensions:2.5 x 1.63 x 5.13 inches
- decongestant:Targets nasal congestion
- active ingredients:Xylitol
- saline solution:Nasal saline spray
9.0

Excellent

Our Rating

9.7
Simple to use

9.7
For traveling

9.3
worth the money
7

Xlear
Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)
Main highlights

Natural Decongestant and Moisturizer
Xlear Nasal Spray gently cleans, moisturizes, and decongests sinuses naturally with xylitol.

Ideal for Chronic Sinus Issues
Perfect for individuals with recurring sinus infections and allergies.

Highly Effective for Sinus Relief
Users praise its immediate relief from congestion and improved breathing.
Key specs
- features:Natural, safe for kids
- product dimensions:2.5 x 1.63 x 5.13 inches
- decongestant:Targets nasal congestion
- active ingredients:Xylitol
- saline solution:Nasal saline spray
8.9

Very Good

Our Rating

9.7
Simple to use

9.7
For traveling

9.3
worth the money
8

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- saline solution:N/A
8.8

Very Good

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
9

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- saline solution:N/A
8.7

Very Good

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
10

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
8.6

Very Good

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing

10 Best nasal spray for sinusitis of 2026

1

Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

9.5

9.3

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

3

Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

4

Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

5

Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

6

Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)

9.7

9.7

9.3

7

Xlear Natural Nasal Spray with Xylitol, 1.5 fl oz (Pack of 1)

9.7

9.7

9.3

8

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

9

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

10

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

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