10 Best nasal spray for sinusitis of 2025

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Best Choice

1

Flonase
Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief 144 Sprays, Bonus Pack of Tissues
Main highlights

24-Hour Non-Drowsy Relief
Flonase provides 24-hour non-drowsy relief for nasal congestion, runny nose, and itchy eyes.

Year-Round Allergy Protection
Ideal for indoor and outdoor allergies, including pollen, mold, and pet dander.

Highly Effective Performance
Customers praise its effectiveness despite occasional spray clogging issues.
9.6

Exceptional

Our Rating

9.3
Gentle

9.1
worth the money
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Value for Money

2

Vicks
Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2
Main highlights

Instant Sinus Relief
Clears stuffy nose in seconds, works 6x faster than tablets.

Ideal for Cold and Allergy
Effective for congestion and sinus pressure relief day or night.

Praised Metered Mist
Fine mist prevents dripping, ensuring easy and mess-free use.
Key specs
- features:Instant sinus relief
- product dimensions:5.08 x 2.76 x 2.13 inches
- active ingredients:N/A
- decongestant:Nasal Spray
- saline solution:N/A
9.5

Excellent

Our Rating
3

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.3

Excellent

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
4

Afrin
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
Main highlights

Maximum Strength Relief
Afrin No Drip provides instant, long-lasting relief for severe nasal congestion.

Ideal for Allergy Season
Perfect for allergy sufferers needing effective nasal congestion relief.

Long-Lasting Effect
Customers praise its 12-hour effectiveness and non-drip formulation.
9.2

Excellent

Our Rating

9.5
Simple to use

9.1
worth the money

8.9
Moisturizing
5

Beekeeper's Naturals
Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz
Main highlights

Natural Ingredients and Benefits
Formulated with sea salt, propolis, and xylitol for sinus relief.

Ideal for Sinus Congestion
Perfect for relieving congestion caused by pollutants and allergens.

Customer Praised Natural Formula
Highly rated for its natural, chemical-free composition.
Key specs
- effects:Decongestant, reduces swelling
- safety:Non-GMO, non-addictive
- usage:Shake well, spray twice
- formulation:Saline solution, sea salt
- dimensions:1.37 x 1.37 x 5 inches
9.0

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Premium Saline Nasal Moisturizing Spray, 1.5 fl oz (Pack of 1), Clear
Main highlights

Key Features
Contains sodium chloride 0.65% with preservatives, soothes dry nasal passages, and offers non-medicated relief.

Ideal Use Cases
Perfect for relieving dryness from allergies, sinus issues, and cold medications; instantly soothes.

Customer Reviews
Most praised for its effective relief of dry nasal passages and ease of use.
Key specs
- features:Soothes dry nasal passages
- product dimensions:1.53 x 1.53 x 3.98 inches
- active ingredients:Sodium chloride, phenylcarbinol
- decongestant:N/A
- saline solution:Sodium chloride 0.65%
8.9

Very Good

Our Rating

8.9
Simple to use

8.4
worth the money

8.2
Moisturizing
7

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
8.8

Very Good

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
8

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- active ingredients:oxymetazoline hydrochloride 0.05%
- decongestant:Yes
- saline solution:N/A
8.7

Very Good

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
9

Seagate
Seagate Products Homeopathic Olive Leaf Nasal Spray (Pack of 1) 1 Ounce
Main highlights

Safe and Natural Relief
Homeopathic formula with pure, chemical-free ingredients for sinus irritation relief.

Ideal for Chronic Sinus Issues
Designed for those with persistent sinus problems seeking natural alternatives.

Non-Habit Forming Benefit
Praised for being non-addictive and free from side effects.
8.6

Very Good

Our Rating

9.9
quality of ingredients

9.5
worth the money

9.3
Simple to use
10

Mucinex
Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce
Main highlights

Fast Acting Relief
Mucinex Sinus-Max provides quick relief from nasal and sinus congestion.

Ideal for Allergies
Perfect for allergy season, offering targeted congestion relief.

Customer Praised Effectiveness
Users love its fast action and long-lasting congestion relief.
8.4

Good

Our Rating

10 Best nasal spray for sinusitis of 2025

1

Flonase Allergy Relief Nasal Spray, 24-Hour Non-Drowsy Multi-Symptom Relief 144 Sprays, Bonus Pack of Tissues

9.3

9.1

How do we rank?

How do we rank?

Analyzing top stores

2

Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

3

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

4

Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

9.5

9.1

8.9

5

Beekeeper's Naturals Nasal Spray for Adults with Propolis, Xylitol & Saline, Clears Nasal Congestion, Moisturizes Sinus Canal, & Decongest Sinus Cavities, 1 fl oz

6

Amazon Basic Care Premium Saline Nasal Moisturizing Spray, 1.5 fl oz (Pack of 1), Clear

8.9

8.4

8.2

7

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

8

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

9

Seagate Products Homeopathic Olive Leaf Nasal Spray (Pack of 1) 1 Ounce

9.9

9.5

9.3

10

Mucinex Sinus-Max Severe Nasal Congestion Relief Sinus & Allergy Nasal Spray, 0.75 Fluid Ounce

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