February 21, 2026

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10 Best nasal decongestant sprays of 2026

Save up to 21% off

1

Afrin
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
Main highlights

Maximum Strength Relief
Afrin No Drip provides instant, long-lasting relief for severe nasal congestion.

Ideal for Allergy Season
Perfect for allergy sufferers needing effective nasal congestion relief.

Long-Lasting Effect
Customers praise its 12-hour effectiveness and non-drip formulation.
9.9

Exceptional

Our Rating

9.5
Simple to use

9.1
worth the money

8.9
Moisturizing
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Based on millions of stores and reviews

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Analyzing top stores
2

Vicks
Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.7

Exceptional

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
3

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- usage instructions:N/A
9.6

Exceptional

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
4

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- decongestant:Yes
- active ingredients:oxymetazoline hydrochloride 0.05%
- usage instructions:N/A
9.5

Excellent

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
5

Amazon Basic Care
Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Steroid Free, Maximum Strength Plus Menthol 1 fl oz (Pack of 1)

17% Off
Main highlights

Maximum Strength Relief
Provides 12-hour relief from nasal congestion due to colds and allergies.

Ideal for Cold and Allergy Sufferers
Perfect for those needing fast, effective nasal decongestion.

Praised for Value and Performance
Customers appreciate the effective relief and cost savings over name brands.
Key specs
- features:12-hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- decongestant:Yes
- active ingredients:Oxymetazoline HCl
- usage instructions:N/A
9.2

Excellent

Our Rating

9.1
worth the money

8.2
Comfort

8.0
Flavor
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6

Amazon Basic Care
Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Steroid Free, Maximum Strength Plus Menthol 1 fl oz (Pack of 1)

21% Off
Main highlights

Maximum Strength Relief
Provides 12-hour relief from nasal congestion due to colds and allergies.

Ideal for Cold and Allergy Sufferers
Perfect for those needing fast, effective nasal decongestion.

Praised for Value and Performance
Customers appreciate the effective relief and cost savings over name brands.
Key specs
- features:12-hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- decongestant:Yes
- active ingredients:Oxymetazoline HCl
- usage instructions:N/A
8.9

Very Good

Our Rating

9.1
worth the money

8.2
Comfort

8.0
Flavor
7

Generic

No Drip Nasal Spray, Equate Pump Mist, 12 Hour, Oxymetazoline Hcl, 1 fl oz. (Pack 1)
8.7

Very Good

Our Rating
8

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
8.6

Very Good

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
9

Afrin
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
Main highlights

12 Hour Relief and Moisture
Afrin No Drip Extra Moisturizing provides up to 12 hours of congestion relief while soothing dry nasal passages.

Ideal for Nighttime and Travel
Perfect for nighttime congestion relief and reducing in-flight discomfort from sinus pressure.

Instant and Effective Congestion Relief
Praised for its fast-acting relief of nasal and sinus congestion, especially during sleep and travel.
Key specs
- features:No drip, 12 hours relief
- product dimensions:1.88 x 1.25 x 4.5 inches
- decongestant:Nasal decongestant pump mist
- active ingredients:N/A
- usage instructions:Spray two or three times
8.4

Good

Our Rating

9.9
sweat control

9.3
pain management

8.7
Simple to use
10

Afrin
Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
Main highlights

12 Hour Relief and Moisture
Afrin No Drip Extra Moisturizing provides up to 12 hours of congestion relief while soothing dry nasal passages.

Ideal for Nighttime and Travel
Perfect for nighttime congestion relief and reducing in-flight discomfort from sinus pressure.

Instant and Effective Congestion Relief
Praised for its fast-acting relief of nasal and sinus congestion, especially during sleep and travel.
Key specs
- features:No drip, 12 hours relief
- product dimensions:1.88 x 1.25 x 4.5 inches
- decongestant:Nasal decongestant pump mist
- active ingredients:N/A
- usage instructions:Spray two or three times
8.2

Good

Our Rating

9.9
sweat control

9.3
pain management

8.7
Simple to use

10 Best nasal decongestant sprays of 2026

1

Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

9.5

9.1

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

9.5

9.3

9.1

3

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

4

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

5

Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Steroid Free, Maximum Strength Plus Menthol 1 fl oz (Pack of 1)

9.1

8.2

8.0

6

Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Steroid Free, Maximum Strength Plus Menthol 1 fl oz (Pack of 1)

9.1

8.2

8.0

7

No Drip Nasal Spray, Equate Pump Mist, 12 Hour, Oxymetazoline Hcl, 1 fl oz. (Pack 1)

8

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

9

Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL

9.9

9.3

8.7

10

Afrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL

9.9

9.3

8.7

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