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10 Best nasal decongestant sprays of 2026

Save up to 16% off
  • Best Choice

    1

    (12 pack) Nasal Relief Spray, 12 hour Pump Mist (Oxymetazoline HCL) 0.5 fl oz
    ASSURED
    9.8
    Exceptional

    (12 pack) Nasal Relief Spray, 12 hour Pump Mist (Oxymetazoline HCL) 0.5 fl oz

    • asin:B006V6H4GU
    • product dimensions:11.57 x 4.84 x 2.64 inches 0.5 ounces
    • date first available:January 9, 2012
    • item model number:986845
    • manufacturer:Assured
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  • Value for Money

    2

    Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
    Afrin
    9.7
    Exceptional

    Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

    • asin:B07HG5JMBR
    • product dimensions:1.88 x 2.75 x 4.5 inches; 2.4 ounces
    • date first available:September 10, 2018
    • item model number:CSAVBLK;ASD;LF
    • manufacturer:Bayer Healthcare LLC

  • 3

    Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)
    Vicks
    9.5
    Excellent

    Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

    • is discontinued by manufacturer:No
    • asin:B073MY31H6
    • product dimensions:2.56 x 3.86 x 5.4 inches; 1 ounces
    • date first available:April 10, 2017
    • manufacturer:Procter & Gamble - HABA Hub

  • 4

    Mucinex Sinus-Max Nasal Spray Decongestant, 12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants for Adults & Sinus Congestion, Clear & Cool 3/4 Fl Oz(22ML)
    Mucinex
    9.4
    Excellent

    Mucinex Sinus-Max Nasal Spray Decongestant, 12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants for Adults & Sinus Congestion, Clear & Cool 3/4 Fl Oz(22ML)

    • is discontinued by manufacturer:No
    • asin:B0046KI188
    • product dimensions:1.25 x 1.81 x 4.75 inches; 0.1 ounces
    • date first available:October 9, 2010
    • manufacturer:Reckitt Benckiser

  • 5

    Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fl Oz (Pack of 3)
    berkley jensen
    9.3
    Excellent

    Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fl Oz (Pack of 3)

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  • 6

    Afrin No Drip Extra Moisturizing Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Sinus Pressure and Dry Nasal Passages, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
    Afrin
    9.2
    Excellent

    Afrin No Drip Extra Moisturizing Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Sinus Pressure and Dry Nasal Passages, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

    • asin:B08H9CKYKL
    • product dimensions:1.88 x 2.75 x 4.5 inches 1.92 ounces
    • date first available:September 1, 2020
    • item model number:W650
    • manufacturer:AmazonUs/BAYR7

  • 7

    MAJOR Maximum Strength Nasal Decongestant Spray, Oxymetazoline HCl 0.05% Pump Mist, Non-Drowsy Nasal Spray, up to 12-Hour Relief from Nasal Congestion, Colds, and Allergies 1 Fl. Oz. (3-Pack)
    MAJOR
    9.1
    Excellent

    MAJOR Maximum Strength Nasal Decongestant Spray, Oxymetazoline HCl 0.05% Pump Mist, Non-Drowsy Nasal Spray, up to 12-Hour Relief from Nasal Congestion, Colds, and Allergies 1 Fl. Oz. (3-Pack)

    • asin:B083VVK3HG
    • product dimensions:N/A
    • date first available:January 15, 2020
    • item model number:N/A
    • manufacturer:Major Pharmaceuticals Rugby Laboratories

  • 8

    Zicam Extreme Congestion Relief No-Drip Nasal Spray with Soothing Aloe Vera, 0.5 oz
    Zicam
    8.8
    Very Good

    Zicam Extreme Congestion Relief No-Drip Nasal Spray with Soothing Aloe Vera, 0.5 oz

    16% Off
    • asin:B0000798CW
    • product dimensions:1.38 x 1.63 x 4.63 inches; 1.44 ounces
    • date first available:January 1, 1999
    • item model number:204120C
    • manufacturer:Matrixx Initiatives, Inc

  • 9

    Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
    Vicks
    8.7
    Very Good

    Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

    • is discontinued by manufacturer:No
    • asin:B01HCX4A3U
    • product dimensions:1.93 x 1.3 x 4.53 inches; 0.48 ounces
    • date first available:June 24, 2016
    • manufacturer:Procter & Gamble

  • 10

    Beekeeper's Naturals Propolis Nasal Rinse Spray Max, w/Saline, Eucalyptus & Oregano, Nasal Spray for Adults, Cleanses, Moisturizes Sinus Canal & Clears Everyday Congestion, 1 fl oz
    Beekeeper's Naturals
    8.6
    Very Good

    Beekeeper's Naturals Propolis Nasal Rinse Spray Max, w/Saline, Eucalyptus & Oregano, Nasal Spray for Adults, Cleanses, Moisturizes Sinus Canal & Clears Everyday Congestion, 1 fl oz

    • is discontinued by manufacturer:N/A
    • asin:B0BQ5JJWW4
    • product dimensions:N/A
    • date first available:May 25, 2023
    • manufacturer:Beekeeper's Naturals

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