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10 Best nasal decongestant sprays of 2025
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- Value for Money
2
MucinexMucinex Mucinex Severe Nasal Congestion Relief Clear & Cool Nasal Spray, Cooling Menthol Flavor (Pack Of 3), 3/4 Fl Ounce
10% OffMain highlights-
Effective Sinus and Allergy Relief
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Ideal for Nighttime Use
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Cooling Menthol Sensation
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3
VicksVicks Sinex SEVERE Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Stuffy Nose due to Cold or Allergy, & Nasal Congestion, Sinus Pressure Relief, 265 Sprays x 2
14% OffMain highlights-
12-Hour Relief from Congestion
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Ideal for Cold and Allergy Season
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Instant Effectiveness Praised by Users
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4
Amazon Basic CareAmazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)
Main highlights-
Maximum Strength Relief
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Ideal for Cold and Allergy Sufferers
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Praised for Value and Performance
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5
Amazon Basic CareAmazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights-
12 Hour Relief
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Ideal for Cold and Allergy Relief
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Fast-Acting Relief
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See Today’s Deals & Prices
6
AfrinAfrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
Main highlights-
Maximum Strength Relief
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Ideal for Allergy Season
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Long-Lasting Effect
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7
AfrinAfrin No Drip Extra Moisturizing 12 Hour Nasal Congestion Relief Pump Mist, Sinus Spray Decongestant - 15 mL
Main highlights-
12 Hour Relief and Moisture
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Ideal for Nighttime and Travel
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Instant and Effective Congestion Relief
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8
Amazon Basic CareAmazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 fl oz (Pack of 1)
Main highlights-
12 Hour Relief
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Best for Cold and Allergy Relief
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Customer Praise for Effectiveness
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9
VicksVicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights-
Instant Relief and Long-Lasting Effect
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Effective for Cold and Allergy Relief
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User Praise for Comfort and Efficacy
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10
Amazon Basic CareAmazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)
Main highlights-
Key Features
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Ideal Use Cases
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Customer Praise
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