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10 Best nasal decongestant sprays of 2026

Save up to 14% off
  • Best Choice

    1

    Amazon Basic Care No Drip Nasal Spray, 12 Hour Maximum Strength Nasal Decongestant, Oxymetazoline HCl, Fast-Acting Sinus Pressure Relief, 1 fl oz (Pack of 1)
    Amazon Basic Care
    9.9
    Exceptional

    Amazon Basic Care No Drip Nasal Spray, 12 Hour Maximum Strength Nasal Decongestant, Oxymetazoline HCl, Fast-Acting Sinus Pressure Relief, 1 fl oz (Pack of 1)

    • asin:B07MLTLN75
    • product dimensions:1.31 x 1.94 x 4.88 inches 1.76 ounces
    • date first available:March 1, 2019
    • item model number:B07MLTLN75
    • manufacturer:Amazon.com Services, LLC.
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  • Value for Money

    2

    Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)
    Vicks
    9.7
    Exceptional

    Vicks Sinex Severe Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Relief from Nasal Congestion, Sinus Pressure Relief, 265 Sprays (2 Count)

    14% Off
    • Formula:Original Ultra Fine Mist
    • Number of Sprays:265 Sprays
    • Type:Nasal Spray
    • Count:2
    • Relief Duration:12-hour

  • 3

    Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2
    Vicks
    9.6
    Exceptional

    Vicks Sinex Severe Nasal Spray, Moisturizing Ultra Fine Mist with Aloe, Decongestant Medicine, Relief from Stuffy Nose Due to Cold or Allergy, Nasal Congestion & Sinus Pressure Relief, 265 Sprays x 2

    • asin:B0D69BZFV6
    • product dimensions:N/A
    • date first available:June 6, 2024
    • item model number:N/A
    • manufacturer:Procter & Gamble

  • 4

    Mucinex Sinus-Max Nasal Spray Decongestant, 12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants for Adults & Sinus Congestion, Clear & Cool 3/4 Fl Oz(22ML)
    Mucinex
    9.5
    Excellent

    Mucinex Sinus-Max Nasal Spray Decongestant, 12 Hour Over-The-Counter Medication Nose Spray for Sinus Relief, Nasal Decongestants for Adults & Sinus Congestion, Clear & Cool 3/4 Fl Oz(22ML)

    13% Off

  • 5

    Afrin No Drip Severe Congestion Nasal Spray Twin Pack, Non-Drowsy, Fast-Acting Nasal Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
    Afrin
    9.4
    Excellent

    Afrin No Drip Severe Congestion Nasal Spray Twin Pack, Non-Drowsy, Fast-Acting Nasal Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

    • asin:B07HG5JMBR
    • product dimensions:1.88 x 2.75 x 4.5 inches; 2.4 ounces
    • date first available:September 10, 2018
    • item model number:CSAVBLK;ASD;LF
    • manufacturer:Bayer Healthcare LLC
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  • 6

    Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Maximum Strength Plus Menthol, Allergy Relief, 1 fl oz (Pack of 1)
    Amazon Basic Care
    9.3
    Excellent

    Amazon Basic Care No Drip Severe 12 Hour Nasal Decongestant Pump Mist, Maximum Strength Plus Menthol, Allergy Relief, 1 fl oz (Pack of 1)

    • asin:B07MLTLN74
    • product dimensions:1.31 x 1.94 x 4.88 inches; 1.76 ounces
    • date first available:March 1, 2019
    • item model number:B07MLTLN74
    • manufacturer:Amazon.com Services, LLC.

  • 7

    Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fluid Ounce (Pack of 3)
    berkley jensen
    9.0
    Excellent

    Berkley Jensen No Drip Severe Congestion Nasal Spray - Maximum Strength Decongestant with Oxymetazoline HCl & Menthol - Pump Mist Applicator, No Steroid, 12 Hour Relief, 1 Fluid Ounce (Pack of 3)

  • 8

    Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Sinus Pressure Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
    Amazon Basic Care
    8.9
    Very Good

    Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Sinus Pressure Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

    • asin:B08ZF4QDKG
    • product dimensions:1.31 x 2.13 x 4.88 inches 2.08 ounces
    • date first available:July 15, 2021
    • item model number:N/A
    • manufacturer:Amazon.com Services, LLC.

  • 9

    MAJOR Maximum Strength Nasal Decongestant Spray 0.05%, 1 Fl Oz, (6-Pack)
    MAJOR
    8.8
    Very Good

    MAJOR Maximum Strength Nasal Decongestant Spray 0.05%, 1 Fl Oz, (6-Pack)

    • asin:B083VVHXR5
    • product dimensions:N/A
    • date first available:January 15, 2020
    • item model number:N/A
    • manufacturer:Major Pharmaceuticals

  • 10

    MAJOR Maximum Strength Nasal Decongestant Spray 0.05%, 1 Fl Oz, (3-Pack)
    MAJOR
    8.7
    Very Good

    MAJOR Maximum Strength Nasal Decongestant Spray 0.05%, 1 Fl Oz, (3-Pack)

    • asin:B083VVK3HG
    • product dimensions:N/A
    • date first available:January 15, 2020
    • item model number:N/A
    • manufacturer:Major Pharmaceuticals Rugby Laboratories