September 14, 2025

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10 Best nasal decongestant sprays of 2025

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Best Choice

1

ASSURED
(12 pack) Nasal Relief Spray, 12 hour Pump Mist (Oxymetazoline HCL) 0.5 fl oz
Main highlights

Convenient Bulk Purchase
Family Care Nasal Relief comes in a pack of twelve bottles per order, providing a cost-effective solution for frequent users.

Ideal for Sinus and Allergy Relief
Perfect for individuals with severe sinus issues, allergies, or dry nose, offering prolonged relief and easy bulk purchase options.

Highly Effective and Long-Lasting
Customers frequently praise its effectiveness and long-lasting relief, with many noting it works as well as or better than more expensive brands.
Key specs
- features:Family Care Nasal Relief
- product dimensions:11.57 x 4.84 x 2.64 inches
- active ingredients:N/A
- decongestant:N/A
- usage instructions:N/A
9.8

Exceptional

Our Rating

9.9
worth the money

9.7
For teething

9.5
Simple to use
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Afrin
Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)
Main highlights

Maximum Strength Relief
Afrin No Drip provides instant, long-lasting relief for severe nasal congestion.

Ideal for Allergy Season
Perfect for allergy sufferers needing effective nasal congestion relief.

Long-Lasting Effect
Customers praise its 12-hour effectiveness and non-drip formulation.
9.7

Exceptional

Our Rating

9.5
Simple to use

9.1
worth the money

8.9
Moisturizing
3

Amazon Basic Care
Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)
Main highlights

Maximum Strength Relief
Provides 12-hour relief from nasal congestion due to colds and allergies.

Ideal for Cold and Allergy Sufferers
Perfect for those needing fast, effective nasal decongestion.

Praised for Value and Performance
Customers appreciate the effective relief and cost savings over name brands.
Key specs
- features:12-hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- active ingredients:Oxymetazoline HCl
- decongestant:Yes
- usage instructions:N/A
9.6

Exceptional

Our Rating

9.1
worth the money

8.2
Comfort

8.0
Flavor
4

Vicks
Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

14% Off
Main highlights

12-Hour Relief from Congestion
Provides instant, long-lasting relief from nasal congestion and sinus pressure for up to 12 hours.

Ideal for Cold and Allergy Season
Perfect for treating severe sinus congestion and pressure from colds or allergies.

Instant Effectiveness Praised by Users
Highly rated for its immediate effectiveness in clearing nasal passages.
9.4

Excellent

Our Rating

9.5
Simple to use

9.3
Moisturizing

9.1
worth the money
5

Amazon Basic Care
Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides fast, powerful congestion relief for up to 12 hours.

Ideal for Cold and Allergy Relief
Perfect for relieving nasal and sinus congestion due to colds and allergies.

Fast-Acting Relief
Customers praise its quick effectiveness in alleviating stuffy noses.
Key specs
- features:12-hour relief, fast-acting
- product dimensions:1.31 x 2.13 x 4.88 inches
- active ingredients:oxymetazoline hydrochloride 0.05%
- decongestant:Yes
- usage instructions:N/A
9.3

Excellent

Our Rating

8.0
worth the money

8.0
Simple to use

8.0
Comfort
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6

MAJOR

MAJOR 12-Hour Nasal Decongestant Spray-Oxymetazoline Hydrochloride 0.05% Nose Spray for Adults and Kids - Soothing Pump Mist for Cold, Allergy, Nasal Congestion, and Sinus Relief - 1 Fl. Oz.(3 Pack)
9.2

Excellent

Our Rating
7

Vicks
Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays
Main highlights

Instant Relief and Long-Lasting Effect
Provides instant, 12-hour relief from nasal congestion and sinus pressure.

Effective for Cold and Allergy Relief
Ideal for severe congestion and sinus pressure from colds or allergies.

User Praise for Comfort and Efficacy
Praised for its effective relief without side effects or irritation.
Key specs
- effects:Reduces sinus pressure
- safety:HSA and FSA eligible
- usage:Nasal congestion relief
- formulation:Nasal Spray
- dimensions:1.93 x 1.3 x 4.53 inches
9.1

Excellent

Our Rating

9.7
worth the money

9.7
Simple to use

9.5
Moisturizing
8

Amazon Basic Care
Amazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 fl oz (Pack of 1)
Main highlights

12 Hour Relief
Provides maximum strength nasal congestion relief for 12 hours.

Best for Cold and Allergy Relief
Ideal for relieving nasal congestion from colds and allergies.

Customer Praise for Effectiveness
Praised for opening nasal passages quickly and effectively.
Key specs
- features:12 hour relief, no drip
- product dimensions:1.31 x 1.94 x 4.88 inches
- active ingredients:Oxymetazoline HCl
- decongestant:Yes
- usage instructions:N/A
9.0

Excellent

Our Rating

8.9
Simple to use

8.7
worth the money

8.2
Flavor
9

Family Care
FamilyCare Nasal Relief Spray, Pump Mist, Anti-drip, Severe Congestion, (Oxymetazoline HCI) 12 Hours, 3 Pack

39% Off
Main highlights

Long-Lasting Relief
Provides up to 12 hours of nasal congestion relief with anti-drip formula.

Ideal for Severe Congestion
Perfect for quick relief from severe nasal congestion and stuffiness.

Instant Breathing
Users praise its ability to deliver instant breathing relief.
8.7

Very Good

Our Rating
10

Amazon Basic Care
Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)
Main highlights

Key Features
Fast-acting phenylephrine HCl for up to four hours of nasal congestion relief, non-drowsy formula, suitable for ages 12 and older.

Ideal Use Cases
Effective for relieving nasal and sinus congestion, swollen nasal membranes, and sinus pressure, ideal for daytime use.

Customer Praise
Users highly appreciate its fast relief for nasal congestion, highlighting its effectiveness and the convenience of a non-drowsy formula.
Key specs
- features:Fast-acting, non-drowsy
- product dimensions:1.31 x 2.13 x 4.88 inches
- active ingredients:Phenylephrine hydrochloride 1%
- decongestant:Phenylephrine hydrochloride
- usage instructions:For ages 12 years and older
8.6

Very Good

Our Rating

8.2
Long life

8.0
worth the money

8.0
Comfort

10 Best nasal decongestant sprays of 2025

1

(12 pack) Nasal Relief Spray, 12 hour Pump Mist (Oxymetazoline HCL) 0.5 fl oz

9.9

9.7

9.5

How do we rank?

How do we rank?

Analyzing top stores

2

Afrin No Drip Severe Congestion Nasal Mist Twin Pack, Non-Drowsy, Fast-Acting Decongestant for Nasal Congestion and Sinus Pressure Relief, Adults and Children 6 and Older, .5 fl oz (Pack of 2)

9.5

9.1

8.9

3

Amazon Basic Care No Drip Severe Congestion Nasal Pump Mist Spray, 12 Hour Relief, Oxymetazoline HCl, Maximum Strength Plus Menthol, Steroid Free, 1 fl oz (Pack of 1)

9.1

8.2

8.0

4

Vicks Sinex SEVERE Allergy & Sinus Nasal Spray, Original Ultra Fine Mist, Decongestant Medicine, Relief from Nasal Congestion due to Cold or Allergy, Sinus Pressure Relief, 265 Sprays x 2

9.5

9.3

9.1

5

Amazon Basic Care Maximum Strength 12 Hour Nasal Spray, Oxymetazoline HCl Solution, Congestion Relief, Cold and Allergy Medicine, Decongestant, 1 fl oz (Pack of 1)

8.0

8.0

8.0

6

MAJOR 12-Hour Nasal Decongestant Spray-Oxymetazoline Hydrochloride 0.05% Nose Spray for Adults and Kids - Soothing Pump Mist for Cold, Allergy, Nasal Congestion, and Sinus Relief - 1 Fl. Oz.(3 Pack)

7

Vicks Sinex Severe Nasal Spray with Moisturizing Ultra Fine Mist, Decongestant for Stuffy Nose Relief from Cold, Allergy, Sinus Pressure - 265 Sprays

9.7

9.7

9.5

8

Amazon Basic Care No Drip Nasal Spray, 12 Hour Nasal Decongestant, Pump Mist, Oxymetazoline HCl, Cold and Allergy Nasal Spray, 1 fl oz (Pack of 1)

8.9

8.7

8.2

9

FamilyCare Nasal Relief Spray, Pump Mist, Anti-drip, Severe Congestion, (Oxymetazoline HCI) 12 Hours, 3 Pack

10

Amazon Basic Care Nasal Four Nasal Spray, Phenylephrine Hydrochloride 1 Percent, Nasal Decongestant, 1 fl oz (Pack of 1)

8.2

8.0

8.0

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