10 Best mucus reliefs of 2025

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1

WELMATE
WELMATE - Mucus Relief - Guaifenesin 1200 mg Maximum Strength - Extended-Release Expectorant Tablets - Helps Clear Chest Congestion & Loosen Mucus - 12 Hour Relief - 100 Count
Main highlights

Extended Relief Bi-Layer
Unique bi-layer tablet provides immediate and extended relief for up to 12 hours.

Ideal for Chest Congestion
Perfect for reducing chest congestion caused by colds, infections, or irritants.

Easy to Swallow
Customers praise its effectiveness despite size; lasts long and works well.
Key specs
- form:Tablet
- active ingredient:Guaifenesin 1200mg
- symptom relief:Chest congestion
- dosage:1 tablet every 12 hours
- target age:12 years and older
9.8

Exceptional

Our Rating

9.9
worth the money

9.9
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Value for Money

2

Guardian
Guardian Mucus Relief, 600mg Guaifenesin 12 Hour Extended Release, Chest Congestion Expectorant (100 Count Bottle)
Main highlights

Extended Relief and Fast Action
600mg Guaifenesin tablets provide extended 12-hour relief, starting to work immediately to relieve chest congestion and loosen mucus.

Ideal for Cold and Allergy Season
Perfect for managing chest congestion and productive coughs during cold and allergy seasons.

Convenient Bottle Packaging
Customers appreciate the bottle packaging, which is easier to handle than foil-backed blister packs.
9.7

Exceptional

Our Rating

9.7
quality of ingredients

9.5
worth the money

9.3
simple to consume
3

ValuMeds
ValuMeds Mucus Relief Guaifenesin 400mg (200 Caplets) | Maximum Strength | Mucus Thinning for Colds, Chest Congestion, Flu, Coughing | Expectorant & Decongestant

20% Off
Main highlights

Maximum Strength Relief
Each caplet contains 400mg of Guaifenesin for potent mucus relief.

Ideal for Chest Congestion
Perfect for adults needing relief from stubborn chest congestion.

Praised for Effectiveness
Customers appreciate its ability to quickly ease respiratory discomfort.
Key specs
- form:Caplets
- active ingredient:Guaifenesin 400mg
- symptom relief:Chest congestion
- dosage:400mg
- target age:Adults
9.5

Excellent

Our Rating
4

HEALTH LFE
HEALTH LFE Mucus Relief Guaifenesin Caplets 400 mg, Immediate Release Fast Acting Expectorant, Thin and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (Medium, 200 Count)
Main highlights

Fast Acting Relief
Guaifenesin provides quick relief by loosening and thinning mucus.

Ideal for Chest Congestion
Perfect for colds, flu, and allergies to relieve chest congestion.

Praised Value
Customers appreciate the cost-effectiveness compared to name brands.
Key specs
- form:Tablet
- active ingredient:Guaifenesin
- symptom relief:Chest congestion
- dosage:400 mg
- target age:N/A
9.3

Excellent

Our Rating
5

GenCare
GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies

21% Off
Main highlights

Fast Relief with Guaifenesin
GenCare Mucus Relief contains 400mg Guaifenesin to thin mucus, easing breathing and expelling phlegm.

Effective for Colds and Flu
Ideal for combatting chest congestion, mucus, and bronchial secretions caused by colds and flu.

Cost-Effective Alternative
Praised for being more affordable than Mucinex, with similar active ingredients and effectiveness.
Key specs
- form:Tablets
- active ingredient:Guaifenesin
- symptom relief:Mucus and phlegm
- dosage:N/A
- target age:12 years and up
9.2

Excellent

Our Rating

8.9
worth the money

8.7
simple to consume

8.0
Flavor
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6

Amazon Basic Care
Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets
Main highlights

Powerful Cough and Congestion Relief
Combines 1200 mg guaifenesin and 60 mg dextromethorphan HBr for maximum strength relief.

Best for Severe Cold and Allergies
Perfect for managing tough cold symptoms and allergy-related coughing.

Customer Praised Effectiveness
Highly rated for alleviating cough and congestion, comparable to Mucinex.
Key specs
- active ingredient:dextromethorphan HBr, guaifenesin
- formulation:tablets
- flavor:N/A
- pack size:N/A
- sugar free:N/A
9.1

Excellent

Our Rating

9.1
worth the money

8.4
simple to consume

8.2
Flavor
7

HealthA2Z
HealthA2Z® Mucus Relief | Guaifenesin 400mg | 300 Counts |No Benzene | Immediate Release | Expectorant
Main highlights

Immediate Release Expectorant
HealthA2Z Mucus Relief offers quick relief by thinning and loosening mucus, making it easier to expel.

Ideal for Congestion Relief
Perfect for individuals needing targeted relief from mucus congestion in the nose, throat, and sinuses.

Affordable Alternative to Brand Names
Customers appreciate its effectiveness and significantly lower cost compared to similar brand-name products.
8.9

Very Good

Our Rating

9.5
worth the money

8.4
simple to consume

8.0
Flavor
8

Amazon Basic Care
Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant Extended-Release Tablets, 42 Count
Main highlights

Powerful Cough and Congestion Relief
Contains 1200 mg of guaifenesin and 60 mg of dextromethorphan HBr for maximum strength relief.

Ideal for Persistent Coughs
Great for managing severe cold symptoms and allergy-related coughing episodes.

Highly Effective Cough Suppressant
Customers appreciate its ability to alleviate cough and congestion effectively.
8.8

Very Good

Our Rating

9.1
worth the money

8.2
simple to consume

8.2
Flavor
9

Mucinex

Mucinex Rapid Clear Maximum Strength Cold Medicine & Expectorant, Fever, Pain, Headache, & Excess Mucus Relief with Acetaminophen & Guaifenesin, Rapid Release Caplets for Adults, 20 Count
8.6

Very Good

Our Rating
10

Amazon Basic Care
Amazon Basic Care Guaifenesin Cough and Mucus Relief Extended-Release Tablets, 600 mg, 12 Hour Expectorant, 20 Count
Main highlights

Effective 12-Hour Relief
Amazon Basic Care Guaifenesin Tablets provide up to 12 hours of chest congestion relief, helping to thin and loosen mucus effectively.

Best for Chest Congestion
Ideal for adults and children 12+ needing long-lasting relief from chest congestion due to mucus.

Praised for Cost Efficiency
Customers appreciate the cost-effectiveness, noting it's cheaper than pharmacy options and name brands.
Key specs
- form:Extended-Release Tablets
- active ingredient:Guaifenesin 600 mg
- symptom relief:Chest congestion relief
- dosage:600 mg
- target age:12 years and older
8.5

Good

Our Rating

9.7
quality of ingredients

9.5
simple to consume

9.3
worth the money

10 Best mucus reliefs of 2025

1

WELMATE - Mucus Relief - Guaifenesin 1200 mg Maximum Strength - Extended-Release Expectorant Tablets - Helps Clear Chest Congestion & Loosen Mucus - 12 Hour Relief - 100 Count

9.9

9.9

How do we rank?

How do we rank?

Analyzing top stores

2

Guardian Mucus Relief, 600mg Guaifenesin 12 Hour Extended Release, Chest Congestion Expectorant (100 Count Bottle)

9.7

9.5

9.3

3

ValuMeds Mucus Relief Guaifenesin 400mg (200 Caplets) | Maximum Strength | Mucus Thinning for Colds, Chest Congestion, Flu, Coughing | Expectorant & Decongestant

4

HEALTH LFE Mucus Relief Guaifenesin Caplets 400 mg, Immediate Release Fast Acting Expectorant, Thin and Loosens Mucus, Relieves Chest Congestion, Cough, Cold and Flu (Medium, 200 Count)

5

GenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies

8.9

8.7

8.0

6

Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets

9.1

8.4

8.2

7

HealthA2Z® Mucus Relief | Guaifenesin 400mg | 300 Counts |No Benzene | Immediate Release | Expectorant

9.5

8.4

8.0

8

Amazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant Extended-Release Tablets, 42 Count

9.1

8.2

8.2

9

Mucinex Rapid Clear Maximum Strength Cold Medicine & Expectorant, Fever, Pain, Headache, & Excess Mucus Relief with Acetaminophen & Guaifenesin, Rapid Release Caplets for Adults, 20 Count

10

Amazon Basic Care Guaifenesin Cough and Mucus Relief Extended-Release Tablets, 600 mg, 12 Hour Expectorant, 20 Count

9.7

9.5

9.3

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