10 Best lidocaine creams of 2025

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Best Choice

1

Curist
Curist 5% Lidocaine Cream Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively with 5% Lidocaine Numbing Cream - (3 Pack - 6 oz Tube)
Main highlights

Key Features
USA-made 5% Lidocaine cream offers fast pain, itch relief, and numbing. Extra-large tubes provide superior value and effectiveness.

Ideal Use Cases
Perfect for tattoo, microneedling, waxing salons, and medical spas. Also effective for hemorrhoid and anorectal discomfort relief.

Customer Praise
Customers frequently highlight its quick-acting, long-lasting relief for various skin pains, surpassing expectations for effectiveness and value.
Key specs
- pack size:5 tubes
- active ingredients:Lidocaine 5%
- application method:Topical
- usage:Tattoo, Microneedling, Waxing
- formulation:Cream
9.6

Exceptional

Our Rating

9.9
worth the money

9.9
pain management
How do we rank?

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Based on millions of stores and reviews

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Analyzing top stores
Value for Money

2

Curist
Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief OTC - 12 oz (Pack of 2) XL Tube 5 Percent Lidocaine Numbing Cream to Numb Effectively (2 Pack - 6 oz Tube)
Main highlights

Maximum Strength Relief
Experience deep pain relief with 5% lidocaine, the strongest OTC formulation.

Versatile Use Cases
Ideal for tattoos, bug bites, hemorrhoids, and muscle pain relief.

Customer Praised Quantity
Generous 12 oz pack offers great value and long-lasting supply.
9.4

Excellent

Our Rating
3

HealthWise

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
9.3

Excellent

Our Rating
4

WELMATE

WELMATE - 5% Lidocaine Numbing Cream, 6oz (170g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care, HSA & FSA Eligible
9.2

Excellent

Our Rating
5

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

28% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
Key specs
- Package Type:Bottle
- Active Ingredients:4% Lidocaine
- Application Method:Topical
- Formulation:Cream
- Target Area:Joints & Muscles
8.9

Very Good

Our Rating

8.4
worth the money

8.4
pain management
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6

Curist
Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)
Main highlights

Maximum Strength Relief
Experience deep pain relief with 5% lidocaine, the strongest OTC formulation.

Versatile Use Cases
Ideal for hemorrhoids, bug bites, rashes, bruises, and more.

Highly Recommended Application
Customers praise its non-greasy, quick-absorbing formula and long-lasting effect.
8.8

Very Good

Our Rating

8.2
pain management

8.0
worth the money
7

Ebanel
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz
Main highlights

Fast-Acting Long-Lasting Relief
Ebanel 5 Lidocaine Cream provides quick, enduring numbing for pain relief and itch reduction.

Ideal for Skin Procedures
Perfect for tattoos, microneedling, waxing, and injections, enhancing comfort during sessions.

Highly Praised Numbing Effect
Customers commend its ability to significantly reduce discomfort and improve treatment experience.
8.7

Very Good

Our Rating

8.9
Simple to use

8.0
Absorbency

8.0
Gentle
8

HealthWise
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic
Main highlights

Powerful Pain Relief
Combines 4% lidocaine and 10% benzyl alcohol for effective pain numbing.

Ideal for Muscle and Joint Aches
Perfect for arthritis, backaches, strains, sprains, and bruises.

Non-Greasy Formula Praised
Customers love the smooth, non-greasy application.
Key specs
- Package Type:Tube
- Active Ingredients:Lidocaine, Benzyl Alcohol
- Application Method:Apply directly to skin
- Formulation:Non-greasy cream
- Target Area:Muscles and joints
8.5

Good

Our Rating
9

HealthWise
HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz
Main highlights

Maximum Strength Relief
Provides temporary relief of minor aches and pains associated with arthritis, strains, and bruises.

Ideal for Minor Aches
Perfect for use on bruises, mild joint pain, and simple backaches.

Praised for Fast Numbing
Customers appreciate the quick numbing effect and excellent value.
Key specs
- Package Type:1.75 oz. bottle
- Active Ingredients:Lidocaine 4%
- Application Method:Apply directly to skin
- Formulation:Non-greasy cream
- Target Area:Muscles and joints
8.4

Good

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
worth the money
10

Hempvana
Hempvana 5% Lidocaine Relief Cream, Maximum Strength, AS-SEEN-ON-TV, Strong Cream, Numbs Irritated Nerves for Fast Anorectal Relief, Non-Greasy, Targeted Long-Lasting Relief. Enriched with Hemp, 3 Oz

33% Off
Main highlights

Fast Effective Relief
Maximum strength 5% lidocaine formula provides quick relief from anorectal discomfort.

Versatile Pain Relief
Ideal for soothing irritated nerves and relieving muscle and joint pain.

Odor-Free Application
Customers praise its non-greasy, odor-free formula for easy application.
Key specs
- Type:Topical analgesic
- Effectiveness:Fast relief
- Formulation:Non-greasy cream
- Ingredients:Hemp seed oil, lidocaine
- Safety:Made in America
8.3

Good

Our Rating

10 Best lidocaine creams of 2025

1

Curist 5% Lidocaine Cream Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively with 5% Lidocaine Numbing Cream - (3 Pack - 6 oz Tube)

9.9

9.9

How do we rank?

How do we rank?

Analyzing top stores

2

Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief OTC - 12 oz (Pack of 2) XL Tube 5 Percent Lidocaine Numbing Cream to Numb Effectively (2 Pack - 6 oz Tube)

3

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic

4

WELMATE - 5% Lidocaine Numbing Cream, 6oz (170g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care, HSA & FSA Eligible

5

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

6

Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief - 6 oz (170 g) XL Tube - Numb Quickly & Effectively Numbing Formulation - (1 Pack - 6 oz Tube)

8.2

8.0

7

Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

8.9

8.0

8.0

8

HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic

9

HealthWise Maximum Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 1.75 Oz

8.2

8.0

8.0

10

Hempvana 5% Lidocaine Relief Cream, Maximum Strength, AS-SEEN-ON-TV, Strong Cream, Numbs Irritated Nerves for Fast Anorectal Relief, Non-Greasy, Targeted Long-Lasting Relief. Enriched with Hemp, 3 Oz

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