10 Best lidocaine creams of 2025

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Best Choice

1

Curist
Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief OTC - 12 oz (Pack of 2) XL Tube 5 Percent Lidocaine Numbing Cream to Numb Effectively (2 Pack - 6 oz Tube)
Main highlights

Maximum Strength Relief
Experience deep pain relief with 5% lidocaine, the strongest OTC formulation.

Versatile Use Cases
Ideal for tattoos, bug bites, hemorrhoids, and muscle pain relief.

Customer Praised Quantity
Generous 12 oz pack offers great value and long-lasting supply.
9.7

Exceptional

Our Rating
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Value for Money

2

WELMATE

WELMATE - 5% Lidocaine Numbing Cream, 6oz (170g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care
9.5

Excellent

Our Rating
3

HealthWise

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic
9.4

Excellent

Our Rating
4

Aspercreme
Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

34% Off
Main highlights

Fast-Acting Numbing Relief
Contains 4% lidocaine for quick, effective pain relief.

Ideal for Joint and Muscle Pain
Perfect for arthritis, backaches, sprains, and strains.

Praised for Ease of Use
Customers love its ease of application and effectiveness.
Key specs
- Package Type:Bottle
- Active Ingredients:4% Lidocaine
- Application Method:Topical
- Formulation:Cream
- Target Area:Joints & Muscles
9.1

Excellent

Our Rating

8.4
worth the money

8.4
pain management
5

WELMATE
WELMATE - 5% Lidocaine Numbing Cream, 2oz (60g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care
Main highlights

Maximum Strength Relief
Contains 5% Lidocaine for effective relief from pain, itching, and soreness.

Ideal for Medical Procedures
Perfect for numbing before tattoos, piercings, and injections.

Highly Praised for Injection Use
Customers appreciate its effectiveness for numbing during injections.
Key specs
- active ingredients:5% Lidocaine
- application method:Apply to skin
- usage:Tattoo, piercings, waxing
- formulation:Topical numbing cream
- pain relief:Aches, pains, itching
8.8

Very Good

Our Rating
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6

Neosporin
Neosporin + Lidocaine First Aid Antibiotic Ointment, Maximum Strength & Fast-Acting Topical Pain Reliever, 24-Hour Infection Protection That Numbs Away The Pain, Bacitracin Zinc, 0.5 oz

23% Off
Main highlights

24-Hour Infection Protection
Offers round-the-clock protection against infection with trusted antibiotics.

Ideal for Minor Wounds
Perfect for treating minor cuts, scrapes, and burns effectively.

Highly Praised Numbing Effect
Customers love the fast-acting lidocaine for pain relief.
Key specs
- Active Ingredients:Bacitracin zinc, neomycin, polymyxin B
- Usage:First aid for cuts
- Volume:0.5-ounce
- Formulation:Ointment
- Packaging:Tube
8.6

Very Good

Our Rating
7

HealthWise
HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic
Main highlights

Powerful Pain Relief
Combines 4% lidocaine and 10% benzyl alcohol for effective pain numbing.

Ideal for Muscle and Joint Aches
Perfect for arthritis, backaches, strains, sprains, and bruises.

Non-Greasy Formula Praised
Customers love the smooth, non-greasy application.
Key specs
- Package Type:Tube
- Active Ingredients:Lidocaine, Benzyl Alcohol
- Application Method:Apply directly to skin
- Formulation:Non-greasy cream
- Target Area:Muscles and joints
8.4

Good

Our Rating
8

Ebanel
Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

23% Off
Main highlights

Fast-Acting Long-Lasting Relief
Ebanel 5 Lidocaine Cream provides quick, enduring numbing for pain relief and itch reduction.

Ideal for Skin Procedures
Perfect for tattoos, microneedling, waxing, and injections, enhancing comfort during sessions.

Highly Praised Numbing Effect
Customers commend its ability to significantly reduce discomfort and improve treatment experience.
8.3

Good

Our Rating

8.9
Simple to use

8.0
Absorbency

8.0
Gentle
9

Aspercreme
Aspercreme Essential Oils Lidocaine Pain Relief with No-Mess Roll-On Applicator, Max-Strength Lidocaine Numbs Away Nerve Pain, Moisturizing Aloe Hydrates Skin, Lavender, 2.5 Oz.
Main highlights

Fast-Acting Pain Relief
Topical liquid with 4% lidocaine numbs minor pains quickly.

Ideal for Relaxation
Infused with lavender essential oil for a soothing aroma.

Convenient Roll-On Application
Customers praise the no-mess roll-on applicator and its ease of use.
Key specs
- volume:2.5-oz
- application:Roll-on
- blend:Lidocaine with lavender
- usage:Pain relief
- scent:Lavender
8.0

Good

Our Rating

9.5
Simple to use

9.1
Aroma

8.4
pain management
10

Curist
Curist 5% Lidocaine Cream Topical Pain Relief - Numb Quickly & Effectively with 5% Lidocaine Numbing Cream - (1 Pack - 2 oz Jar)
Main highlights

Strongest OTC Lidocaine
Experience deep pain relief with the strongest formulation of topical lidocaine available OTC.

Ideal for First Aid Kits
Perfect for burns, scrapes, and general pain relief in home kits.

Highly Praised Effectiveness
Customers appreciate its quick absorption and effective pain numbing.
Key specs
- active ingredients:Lidocaine 5%
- application method:Topical
- usage:External use only
- formulation:Cream
- pain relief:Deep pain relief
7.8

Good

Our Rating

10 Best lidocaine creams of 2025

1

Curist 5% Lidocaine Cream Maximum Strength Topical Pain Relief OTC - 12 oz (Pack of 2) XL Tube 5 Percent Lidocaine Numbing Cream to Numb Effectively (2 Pack - 6 oz Tube)

How do we rank?

How do we rank?

Analyzing top stores

2

WELMATE - 5% Lidocaine Numbing Cream, 6oz (170g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care

3

HealthWise Maximum OTC Strength Lidocaine Cream | Numbs Away Pain | Long-Lasting Relief | Non-Greasy | 2.7 Oz | Unscented Formula | Topical Anesthetic

4

Aspercreme Lidocaine Pain Relief Cream Soothes Aggravated Nerves, Numbing Topical Analgesic with Max-Strength 4% Lidocaine & Moisturizing Aloe, 4.3 Oz.

8.4

8.4

5

WELMATE - 5% Lidocaine Numbing Cream, 2oz (60g) - Maximum Strength Lidocaine Cream - Hemorrhoid Relief - External Use Anesthetic, Vitamin E - Child Resistant - Topical Skin Care

6

Neosporin + Lidocaine First Aid Antibiotic Ointment, Maximum Strength & Fast-Acting Topical Pain Reliever, 24-Hour Infection Protection That Numbs Away The Pain, Bacitracin Zinc, 0.5 oz

7

HealthWise Lidocaine Plus+ Cream | Numbs Away Pain | | Non-Greasy | 3.0 Oz | 4% OTC Lidocaine + 10% Benzyl Alcohol | Topical Anesthetic

8

Ebanel 5% Lidocaine Numbing Cream, Pain Relief Burn Itch Numb Cream, Maximum Strength Topical Anesthetic with Allantoin, Vitamin E for Local and Anorectal Uses, Hemorrhoid Treatment, 1.35 Oz

8.9

8.0

8.0

9

Aspercreme Essential Oils Lidocaine Pain Relief with No-Mess Roll-On Applicator, Max-Strength Lidocaine Numbs Away Nerve Pain, Moisturizing Aloe Hydrates Skin, Lavender, 2.5 Oz.

9.5

9.1

8.4

10

Curist 5% Lidocaine Cream Topical Pain Relief - Numb Quickly & Effectively with 5% Lidocaine Numbing Cream - (1 Pack - 2 oz Jar)

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