10 Best flea and tick treatment for cats of 2025

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Best Choice

1

NEXTSTAR
NEXTSTAR Flea and Tick Prevention for Cats, Repellent, and Control, Fast Acting Waterproof Topical Drops for Cats Over 3.5 lbs, 6 Month Dose
Main highlights

Fast-Acting 30-Day Protection
NextStar offers a fast-acting, long-lasting topical solution for monthly flea and tick prevention.

Ideal for Busy Pet Owners
No vet visit needed; easy-to-use, waterproof topical for hassle-free protection.

Customer Praise for Effectiveness
Users appreciate the 7-way pest protection and quick action against fleas and ticks.
Key specs
- Application Method:Topical
- Kill Time:15 minutes
- Target Weight:Over 3.5 lbs
- Active Ingredients:N/A
- Duration:30 days
9.8

Exceptional

Our Rating
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Value for Money

2

Advecta
Advecta Plus Flea Prevention for Cats, Cat and Kitten Treatment & Control, Small and Large, Fast Acting Waterproof Topical Drops, 6 Month Supply
Main highlights

Fast Acting Flea Treatment
Kills fleas within 12 hours and prevents reinfestation by targeting all life stages.

Ideal for Cat Owners
Perfect for cats and kittens 8 weeks and older needing effective flea control.

Customer Praised Ease of Use
Users appreciate the easy application and waterproof formula for hassle-free protection.
Key specs
- Application Method:Topical
- Kill Time:Within 12 hours
- Target Weight:N/A
- Active Ingredients:Imidacloprid, Pyriproxyfen
- Duration:N/A
9.6

Exceptional

Our Rating
3

Woyamay
Woyamay Flea Treatment for Cats, 200 Treats Flea and Tick Prevention for Cats Chewables, Natural Cat Flea and Tick Treatment Chews Daily Oral Flea Supplement, Kitten Cat Flea Treatment, Chicken Flavor
Main highlights

Natural Ingredients and Safety
Veterinarian-approved chews with coconut oil, flaxseed, and brewer's yeast.

Daily Use for All Cats
Suitable for small, medium, and large cats; ideal for daily protection.

Delicious Chicken Flavor
Customers love the easy administration thanks to the tasty flavor.
Key specs
- Application Method:Oral chews
- Kill Time:N/A
- Target Weight:Small, medium, large cats
- Active Ingredients:Coconut oil, flaxseed, yeast
- Duration:Over 3 months
9.5

Excellent

Our Rating
4

PetArmor
PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 6 Dose, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs
Main highlights

Effective Flea and Tick Protection
Kills fleas, ticks, larvae, and eggs for up to 30 days.

Ideal for Cats Over 1.5 lb
Perfect for cats needing monthly flea and tick prevention.

Highly Praised Long-Lasting Impact
Customers appreciate its extended protection and ease of use.
9.3

Excellent

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
Comfort
5

Frontline
FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

22% Off
Main highlights

Waterproof Long-Lasting Protection
Frontline Plus offers waterproof, fast-acting flea and tick control for cats over 1.5 lbs.

Ideal for Infestation Prevention
Perfect for preventing flea infestations and protecting against Lyme disease transmission.

Veterinarian Trusted
Praised for its effectiveness and long-standing trust among veterinarians.
9.1

Excellent

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Simple to take off
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6

Amazon Basics
Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)
Main highlights

Fast-Acting Protection
Begins eliminating fleas and ticks within 24 hours.

Ideal for Multi-Cat Households
Provides six doses, perfect for homes with multiple cats.

High Customer Satisfaction
Praised for affordability and effectiveness in eliminating fleas.
9.0

Excellent

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Comfort
7

ProElobara
Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply
Main highlights

Fast-Acting and Long-Lasting Protection
Provides up to 30 days of continuous protection against fleas and ticks.

Ideal for Cats with Sensitive Skin
Safe and gentle formula suitable for all cats, including kittens and seniors.

Easy to Apply
Topical treatment applied to shoulder blades, praised for ease of use.
8.9

Very Good

Our Rating
8

Advantage
Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 2-Month Supply
Main highlights

Effective Flea Protection
Advantage II provides comprehensive flea protection, killing adult fleas, larvae, and eggs on contact.

Ideal for Large Cats
Perfect for cats over 9 lbs, offering easy monthly application without a prescription.

Quick Results Praised
Customers love its fast action, with noticeable results in just 12 hours.
8.7

Very Good

Our Rating

8.9
Simple to use

8.0
Aroma

8.0
worth the money
9

Hartz
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

16% Off
Main highlights

Effective Flea and Tick Protection
Topical formula kills fleas and deer ticks; includes 3 monthly treatments.

Ideal for Cats and Kittens
Suitable for cats and kittens 12 weeks and older, weighing 5 pounds and over.

Highly Praised for Effectiveness
Customers appreciate its effectiveness in preventing fleas and ticks.
8.4

Good

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
Aroma
10

TevraPet
TevraPet FirstAct Plus Flea and Tick Topical for Cats over 1.5lbs, 3 Dose Waterproof Flea and Tick Control/Prevention for 3 Months
Main highlights

Proven Formula Benefits
Contains fipronil and S-Methoprene, effectively killing fleas, ticks, and lice.

Ideal Use for Indoor Cats
Perfect for indoor cats needing monthly flea and tick prevention.

Ease of Application
Praised for being easy to use and apply.
8.3

Good

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
worth the money