Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service levels, popularity trends, and more. The rankings reflect our opinion and should be a good starting point for shopping. By purchasing the products we rank, you’ll get the lowest price we found while we may receive a commission at no cost to you, which will help us continue to provide you with value.
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10 Best expectorants of 2025
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- Best Choice
1
MucinexMucinex 12 Hour Maximum Strength Extended-Release Tablets, 42 Tablets
Main highlights-
Long-lasting Relief
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Ideal for Cold Season
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Highly Effective Dosage
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- Value for Money
2
Amazon Basic CareAmazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant Extended-Release Tablets, 42 Count
Main highlights-
Powerful Cough and Congestion Relief
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Ideal for Persistent Coughs
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Highly Effective Cough Suppressant
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3
Amazon Basic CareAmazon Basic Care Guaifenesin Cough and Mucus Relief Extended-Release Tablets, 600 mg, 12 Hour Expectorant, 20 Count
28% OffMain highlights-
Effective 12-Hour Relief
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Best for Chest Congestion
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Praised for Cost Efficiency
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4
MucinexMucinex Chest Congestion, Expectorant 12 Hour Extended Release Tablets, 20ct, 600mg Guaifenesin with Extended Relief of Chest Congestion Caused by Excess Mucus. Thins and Loosens Mucus
10% OffMain highlights-
12 Hour Extended Relief
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Ideal for Persistent Congestion
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Highly Praised Effectiveness
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5
GenCareGenCare Mucus Relief Expectorant Guaifenesin 400 mg 200 Tablets Value Pack - Fast Acting Thinning of Mucus for Colds, Chest Congestion, Flu, Coughing and Allergies
17% OffMain highlights-
Fast Relief with Guaifenesin
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Effective for Colds and Flu
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Cost-Effective Alternative
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See Today’s Deals & Prices
6
Amazon Basic CareAmazon Basic Care Maximum Strength Mucus DM, Expectorant and Cough Suppressant, 14 Tablets
Main highlights-
Powerful Cough and Congestion Relief
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Best for Severe Cold and Allergies
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Customer Praised Effectiveness
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7
MucinexMucinex DM Max Liquid Cough & Cold Medicine for Adults, Cold and Flu Medicine for Excess Mucus Relief, Guaifenesin & Dextromethorphan Expectorant & Decongestant for Adults, Dr Recommended, 6.0 Fl Oz
10% OffMain highlights-
Extended Release Relief
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Ideal for Adult Cold Symptoms
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Praised for Rapid Relief
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8
RobitussinRobitussin Cough and Chest Congestion DM, Cough Suppressant and Expectorant, Raspberry Flavor - 8 Fl Oz Bottle
Main highlights-
Fast Relief for Cough and Congestion
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Ideal for Adults and Teens
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Praised for Flavor and Effectiveness
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9
MucinexMucinex 12 Hour Extended Release Tablets, 600 mg Guaifenesin Relieves Chest Congestion Caused by Excess Mucus, #1 Doctor Recommended OTC Expectorant, Blue, 40 Count
35% OffMain highlights-
Extended Relief Duration
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Ideal for Persistent Congestion
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Highly Effective for Chest Congestion
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10
HealthA2ZHealthA2Z® Mucus Relief | Guaifenesin 400mg | Immediate Release | No Benzene | Expectorant (60 Counts)
Main highlights-
Effective Mucus Relief
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Ideal for Night Use
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Cost-Effective Alternative
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