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10 Best cold sore treatments of 2026
Save up to 24% off
Best Choice1
AbrevaAbreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
13% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:1.71 x 5.1 x 5.5 inches; 0.07 ounces
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asin:B071K8PFHG
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date first available:June 1, 2017
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item model number:105788XA
9.9Exceptional
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Value for Money2
Amazon One MedicalCold Sore Treatment | Request a prescription for cold sore medication like valacyclovir (Valtrex) for fever blister outbreak, prevention from an online doctor, NP, or PA
9.7Exceptional
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3
AbrevaAbreva Docosanol 10% Cream Tube, FDA Approved Treatment for Cold Sore/Fever Blister, 2 grams
Key specs-
is discontinued by manufacturer:No
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asin:B000056OWW
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product dimensions:3.44 x 0.81 x 4.75 inches; 0.07 ounces
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date first available:January 1, 1999
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item model number:080130
9.4Excellent
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4
MedermaMederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores
Key specs-
is discontinued by manufacturer:N/A
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product dimensions:6.1 x 4.3 x 0.8 inches 0.63 ounces
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asin:B08MVF9YW1
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date first available:October 16, 2020
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item model number:MDCPZUSA
9.1Excellent
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5
ReleevReleev 1Day Cold Sore Treatment Liquid, Fast-Acting Soothing of Pain and Itching, Topical Care for Fever Blisters & Lip Sores, 0.2 Ounces
11% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:N/A
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asin:B003GD0I5A
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date first available:April 9, 2010
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item model number:WI-5VDE-8YQP
9.0Excellent
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6
Burt's BeesBurt's Bees Cold Sore Treatment and Medicated Lip Balm, With Menthol and Eucalyptus Oil, Natural Origin Skincare, 2 Tubes, 0.07 oz./0.15 oz.
Key specs-
asin:B09CK1V89X
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product dimensions:6 x 5 x 1.25 inches 2.4 ounces
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item model number:TU 1222229
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manufacturer:Burt's Bees, Inc.
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country of origin:USA
8.9Very Good
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7
OrajelOrajel Touch Free Cold Sore Treatment .12oz, Liquid Formula, Provides Immediate & Targeted Pain Relief, Bonus Size, 6 Applicators.
Key specs-
is discontinued by manufacturer:N/A
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product dimensions:4.75 x 3.75 x 1 inches 0.86 ounces
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asin:B09KW5C7XN
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date first available:November 2, 2021
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item model number:SUVELAM
8.8Very Good
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8
AbrevaAbreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Pump
24% OffKey specs-
is discontinued by manufacturer:No
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product dimensions:5.45 x 5 x 1.6 inches 0.07 ounces
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asin:B000UALM1G
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date first available:September 9, 2000
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item model number:80155
8.5Good
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9
OrajelOrajel Moisturelock Cold Sore Symptom Treatment, Cream 0.105 oz (Packaging May Vary)
Key specs-
is discontinued by manufacturer:No
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product dimensions:3.63 x 0.75 x 4.75 inches 0.11 ounces
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asin:B01KHNJ9KG
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date first available:August 19, 2016
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item model number:SPAUSD13643
8.3Good
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10
LyrandaLyranda® - Lysine Cold Sore Treatment - Chewable L-Lysine Tablets - Faster Absorption and Better Hygiene
Key specs-
package dimensions:4.8 x 4.76 x 2.4 inches 3.32 ounces
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asin:B0D94SZYDF
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date first available:July 9, 2024
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manufacturer:Weber&Weber International GmbH
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country of origin:Germany
8.2Good
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