10 Best cold sore treatments of 2026

Save up to 35% off

1

Abreva
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
Main highlights

Fast Healing with Docosanol
Contains 10% docosanol to shorten cold sore duration to 2.5 days.

Ideal for On-the-Go Treatment
Portable tube design perfect for quick, discreet application.

Highly Praised for Effectiveness
Users appreciate fast results and healing of cracked lips.
Key specs
- formula:Docosanol cream
- weight:1.76 ounces
- pain relief:Tingling, pain, burning, itching
- dimensions:1.71 x 5.1 x 5.5 inches
- active ingredients:10% docosanol
9.9

Exceptional

Our Rating

8.7
worth the money

8.4
Flavor
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2

Abreva
Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Pump

35% Off
Main highlights

Rapid Healing Formula
Abreva contains 10% docosanol, proven to heal cold sores in 2.5 days.

Ideal for Early Treatment
Best used at the first sign of a cold sore for maximum effectiveness.

Highly Effective
Customers frequently praise its fast action and reliability against cold sores.
9.6

Exceptional

Our Rating

8.2
Sheerness

8.0
worth the money

8.0
Long life
3

TARO

TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective Relief and Healing - 0.07 oz (2 Pack)
9.5

Excellent

Our Rating
4

TARO

TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective Relief and Healing - 0.07 oz (2 Pack)
9.4

Excellent

Our Rating
5

Mederma
Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores
Main highlights

Fast Healing Hydrocolloid Gel
Ultra-thin hydrocolloid gel accelerates healing and prevents scabbing.

Discreet Social Use
Ideal for social settings, conceals cold sores effectively.

Pain and Itch Relief
Eliminates pain and itchiness, enhancing comfort during healing.
Key specs
- formula:Ultra-thin Hydrocolloid
- weight:0.63 ounces
- pain relief:Relieve pain
- dimensions:6.1 x 4.3 x 0.8 inches
- active ingredients:Hydrocolloid Gel
9.1

Excellent

Our Rating

8.7
Comfort

8.4
Simple to use

8.4
Sheerness
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6

Mederma
Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores
Main highlights

Fast Healing Hydrocolloid Gel
Ultra-thin hydrocolloid gel accelerates healing and prevents scabbing.

Discreet Social Use
Ideal for social settings, conceals cold sores effectively.

Pain and Itch Relief
Eliminates pain and itchiness, enhancing comfort during healing.
Key specs
- formula:Ultra-thin Hydrocolloid
- weight:0.63 ounces
- pain relief:Relieve pain
- dimensions:6.1 x 4.3 x 0.8 inches
- active ingredients:Hydrocolloid Gel
8.8

Very Good

Our Rating

8.7
Comfort

8.4
Simple to use

8.4
Sheerness
7

Campho-Phenique
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz
Main highlights

Pain and Itch Relief
Specially formulated to instantly relieve pain and itch from cold sores and fever blisters.

Versatile Use
Ideal for treating cold sores, fever blisters, insect bites, and minor sunburns.

Quick Healing
Praised for its ability to speed up healing and provide immediate relief.
Key specs
- formula:Specially formulated
- weight:0.23 ounces
- pain relief:Instantly relieves pain & itch
- dimensions:0.75 x 3.31 x 4.09 inches
- active ingredients:N/A
8.6

Very Good

Our Rating

9.3
worth the money

8.0
Flavor
8

Campho-Phenique
Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz
Main highlights

Pain and Itch Relief
Specially formulated to instantly relieve pain and itch from cold sores and fever blisters.

Versatile Use
Ideal for treating cold sores, fever blisters, insect bites, and minor sunburns.

Quick Healing
Praised for its ability to speed up healing and provide immediate relief.
Key specs
- formula:Specially formulated
- weight:0.23 ounces
- pain relief:Instantly relieves pain & itch
- dimensions:0.75 x 3.31 x 4.09 inches
- active ingredients:N/A
8.4

Good

Our Rating

9.3
worth the money

8.0
Flavor
9

Quantum
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

25% Off
Main highlights

Halve Healing Time
Cut cold sore healing time by 50% with L-Lysine.

Ideal for First Signs
Best used at the first sign of a cold sore.

Rapid Results
Praised for quickly reducing cold sore size and discomfort.
8.3

Good

Our Rating

9.3
Moisturizing

9.3
worth the money

8.4
Flavor
10

Quantum
Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

29% Off
Main highlights

Halve Healing Time
Cut cold sore healing time by 50% with L-Lysine.

Ideal for First Signs
Best used at the first sign of a cold sore.

Rapid Results
Praised for quickly reducing cold sore size and discomfort.
8.2

Good

Our Rating

9.3
Moisturizing

9.3
worth the money

8.4
Flavor

10 Best cold sore treatments of 2026

1

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

8.7

8.4

How do we rank?

How do we rank?

Analyzing top stores

2

Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Pump

8.2

8.0

8.0

3

TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective Relief and Healing - 0.07 oz (2 Pack)

4

TARO Cold Sore & Fever Blister Treatment - Fast-Acting Docosanol 10% Cream - Cold Sore & Fever Blister Treatment for Lips, Anti-Itch Formula for Effective Relief and Healing - 0.07 oz (2 Pack)

5

Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores

8.7

8.4

8.4

6

Mederma Cold Sore Discreet Patch - Hydrocolloid Gel, Relieves Redness & Swelling, Conceals Cold Sores

8.7

8.4

8.4

7

Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz

9.3

8.0

8

Campho Phenique Cold Sore and Fever Blister Treatment for Lips, Maximum Strength Provides Instant Relief, Helps Prevent Infection To Promote Healing, Original Gel Formula, 0.23 Oz

9.3

8.0

9

Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

9.3

9.3

8.4

10

Quantum Health Lip Clear Lysine+ Cold Sore Treatment Soothe & Moisturize Mouth Sores - L-Lysine Menthol Calendula & Propolis Ointment - Transparent Fever Blister Healing Balm - 0.25 Oz

9.3

9.3

8.4

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