10 Best cold and flu tablets of 2025

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Best Choice

1

Sambucol
Sambucol Cold and Flu Relief Tablets - Homeopathic Cold Medicine, Cold Remedy for Adults, Black Elderberry for Colds, Zinc Cold Remedy - 60 Count

16% Off
Main highlights

Fast Relief from Cold and Flu
Provides quick relief from symptoms like congestion, sore throat, and coughing.

Ideal for Family Use
Non-drowsy tablets suitable for adults and children during cold and flu season.

Highly Praised Convenience
Customers love the quick-dissolving tablets for their ease of use.
9.8

Exceptional

Our Rating

9.9
Flavor

9.3
For teething

8.0
worth the money
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Value for Money

2

Tylenol
Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

28% Off
Main highlights

Comprehensive Symptom Relief
Tylenol Cold + Flu Severe Medicine Caplets provide multi-symptom relief for fever, aches, sore throat, congestion, and cough.

Ideal for Cold and Flu Season
Perfect for adults and children 12+ needing relief from severe cold and flu symptoms.

Fast Delivery Praised by Customers
Customers appreciate the quick delivery, often arriving earlier than expected, which is a lifesaver during illness.
9.7

Exceptional

Our Rating
3

Amazon Basic Care
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

12% Off
Main highlights

Multi-Symptom Relief
Provides effective relief from headache, fever, sore throat, and more.

Day and Night Use
Ideal for continuous relief of cold and flu symptoms.

Quick Action
Praised for fast-acting relief within a few hours.
9.6

Exceptional

Our Rating

9.3
simple to consume

9.3
Flavor

9.1
worth the money
4

Tylenol
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.
Main highlights

Comprehensive Symptom Relief
Relieves fever, pain, congestion, cough, and loosens mucus.

Ideal for Cold and Flu
Perfect for adults and children 12+ with cold and flu symptoms.

Praised Effectiveness
Customers appreciate its superior efficacy over generic alternatives.
9.5

Excellent

Our Rating

9.9
pain management

9.3
worth the money

8.7
simple to consume
5

ALKA-SELTZER PLUS
Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat 24 Count, Packaging May Vary

21% Off
Main highlights

Fast Relief Formula
Provides liquid fast relief for cold and flu symptoms.

On-the-Go Convenience
Ideal for busy individuals needing quick, portable relief.

Effective Nausea Relief
Effervescence praised for alleviating nausea effectively.
9.4

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
Main highlights

Maximum Strength Multi-Symptom Relief
Provides around-the-clock relief for cold and flu symptoms with a combination of daytime and nighttime caplets.

Ideal for Families and Busy Individuals
Perfect for those needing effective relief during the day and restful sleep at night.

Highly Praised Nighttime Formula
Customers appreciate the nighttime caplets for aiding sleep and symptom relief.
9.2

Excellent

Our Rating

9.3
simple to consume

9.1
worth the money

8.7
Flavor
7

Vicks
Vicks NyQuil Severe Cold, Flu, & Congestion Medicine, 24 Liquicaps, Maximum Strength, 24Count

16% Off
Main highlights

Comprehensive Symptom Relief
Provides maximum strength relief for cough, headache, fever, sore throat, aches, nasal congestion, and more.

Ideal for Severe Cold and Flu
Best suited for tackling severe cold, flu, and congestion symptoms effectively.

Highly Effective for Symptom Management
Customers frequently praise its effectiveness in alleviating multiple symptoms quickly.
9.0

Excellent

Our Rating
8

Sambucol
Sambucol Cold and Flu Relief Tablets - Homeopathic Cold Medicine, Cold Remedy for Adults, Black Elderberry for Colds, Zinc Cold Remedy - 30 Count

25% Off
Main highlights

Fast Cold and Flu Relief
Quick-dissolving tablets provide fast, temporary relief from cold and flu symptoms.

Ideal for Early Symptom Use
Best used at the first sign of cold or flu symptoms.

Praised for Pleasant Taste
Customers love the grape-like flavor and fast-dissolving nature.
8.8

Very Good

Our Rating

9.7
Simple to use

9.7
pain management

9.7
Flavor
9

Amazon Basic Care
Amazon Basic Care Daytime Severe Cold & Flu Relief Caplets, Cold Medication for Severe Cold and Flu Symptoms Like Headache, Fever, Coughing, Chest & Nasal Congestion, Vapor Ice, 24 Count
Main highlights

Key Features
Combines acetaminophen, dextromethorphan, guaifenesin, phenylephrine for comprehensive cold, flu relief. Compares to Vicks DayQuil Severe+ VapoCOOL.

Ideal Use Cases
Effective for daytime relief of severe cold and flu symptoms, including fever, headache, cough, and nasal congestion.

Customer Praise
Users frequently highlight its effectiveness in relieving a wide range of symptoms quickly, appreciating the fast-acting formula.
8.5

Good

Our Rating
10

ALKA-SELTZER PLUS
Alka-Seltzer Plus Power Max Cold & Flu Day+Night Medicine: Cough Suppressant, Cold and Flu Medicine For Adults and Children 12 Years and Older, 36 Count, Packaging May Vary
Main highlights

Comprehensive Cold and Flu Relief
Provides relief from headache, fever, cough, nasal/sinus congestion for adults and children 12+.

Day and Night Use
Ideal for continuous relief with distinct daytime and nighttime formulas.

Praised Smaller Size
Customers appreciate the smaller pill size compared to older versions.
8.4

Good

Our Rating

8.4
simple to consume

8.0
worth the money

10 Best cold and flu tablets of 2025

1

Sambucol Cold and Flu Relief Tablets - Homeopathic Cold Medicine, Cold Remedy for Adults, Black Elderberry for Colds, Zinc Cold Remedy - 60 Count

9.9

9.3

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Tylenol Cold + Flu Severe Medicine Caplets for Cold & Flu Symptom Relief, Fever Reducer, Pain Reliever, Cough Suppressant, Nasal Decongestant & Expectorant with Acetaminophen, 2 pks of 24 ct ea, 48 ct

3

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

9.3

9.3

9.1

4

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

9.9

9.3

8.7

5

Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat 24 Count, Packaging May Vary

6

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

9.3

9.1

8.7

7

Vicks NyQuil Severe Cold, Flu, & Congestion Medicine, 24 Liquicaps, Maximum Strength, 24Count

8

Sambucol Cold and Flu Relief Tablets - Homeopathic Cold Medicine, Cold Remedy for Adults, Black Elderberry for Colds, Zinc Cold Remedy - 30 Count

9.7

9.7

9.7

9

Amazon Basic Care Daytime Severe Cold & Flu Relief Caplets, Cold Medication for Severe Cold and Flu Symptoms Like Headache, Fever, Coughing, Chest & Nasal Congestion, Vapor Ice, 24 Count

10

Alka-Seltzer Plus Power Max Cold & Flu Day+Night Medicine: Cough Suppressant, Cold and Flu Medicine For Adults and Children 12 Years and Older, 36 Count, Packaging May Vary

8.4

8.0

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