10 Best cold and flus of 2025

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Best Choice

1

Vicks

Vicks DayQuil & NyQuil Ultra Concentrated Liquicaps Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 96ct
9.8

Exceptional

Our Rating
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Value for Money

2

Boiron
Boiron Oscillococcinum Natural Relief for Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

22% Off
Main highlights

Comprehensive Flu Symptom Relief
Oscillococcinum helps relieve fatigue, headache, body aches, chills, and fever safely for ages 2 and up.

Ideal for Early Flu Onset
Best used at the first sign of flu-like symptoms to reduce duration and severity.

Customer Praised Quick Dissolving
Sweet-tasting pellets dissolve easily under the tongue, praised for convenience.
Key specs
- active ingredient:Oscillococcinum
- symptom relief:Fatigue, headache, body aches
- form:Pellets
- flavor:Sweet-tasting
- dosage:At first sign of flu
9.7

Exceptional

Our Rating

9.7
simple to consume

9.7
Simple to use

9.7
Flavor
3

Tylenol
Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

19% Off
Main highlights

Comprehensive Cold Flu Relief
24-count pack offers multi-symptom relief for cold and flu.

Day Night Usage
Ideal for day and night relief with separate formulas.

Highly Praised Value
Customers appreciate the value and effectiveness of the product.
Key specs
- features:Cold & flu relief
- product dimensions:4.52 x 0.78 x 2.95 inches
- active ingredients:Acetaminophen, Phenylephrine HCl
- decongestant:Phenylephrine HCl
- saline solution:N/A
9.6

Exceptional

Our Rating
4

Amazon Basic Care
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
Main highlights

Multi-Symptom Relief
Provides effective relief from headache, fever, sore throat, and more.

Day and Night Use
Ideal for continuous relief of cold and flu symptoms.

Quick Action
Praised for fast-acting relief within a few hours.
9.5

Excellent

Our Rating

9.3
simple to consume

9.3
Flavor

9.1
worth the money
5

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.3

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
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6

Amazon Basic Care
Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)
Main highlights

Multi-Symptom Relief
Combines pain relief, cough suppressant, and antihistamine for comprehensive cold and flu care.

Nighttime Use
Ideal for nighttime relief, helping you rest and recover.

Sleep Aid Effectiveness
Praised for its fast-acting sleep-inducing properties.
9.1

Excellent

Our Rating

9.3
worth the money

9.1
Flavor
7

Amazon Basic Care
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
Main highlights

Maximum Strength Multi-Symptom Relief
Provides around-the-clock relief for cold and flu symptoms with a combination of daytime and nighttime caplets.

Ideal for Families and Busy Individuals
Perfect for those needing effective relief during the day and restful sleep at night.

Highly Praised Nighttime Formula
Customers appreciate the nighttime caplets for aiding sleep and symptom relief.
Key specs
- active ingredient:Compare to Vicks DayQuil/NyQuil
- symptom relief:Cold and flu symptoms
- form:Coated caplets
- flavor:Vapor Ice
- dosage:N/A
8.9

Very Good

Our Rating

9.3
simple to consume

9.1
worth the money

8.7
Flavor
8

Mucinex
Mucinex Fast-Max Liquid Gels for Day/Night Cold and Flu, 24 Count

32% Off
Main highlights

Multi-Symptom Relief Efficiency
Provides fast, powerful relief for 9 cold and flu symptoms.

Ideal for Day and Night Use
Designed for comprehensive symptom management, both day and night.

Quick Symptom Relief Praised
Customers appreciate the fast-acting relief, often within two doses.
Key specs
- active ingredient:Acetaminophen, Dextromethorphan, Guaifenesin
- symptom relief:Cold & flu symptoms
- form:Liquid gel
- flavor:N/A
- dosage:1 dose
8.8

Very Good

Our Rating

9.7
quality of ingredients

9.5
pain management

8.0
simple to consume
9

Amazon Basic Care
Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count
Main highlights

Multi-Symptom Relief and Non-Drowsy
Provides relief from headache, fever, sore throat, nasal congestion, and cough without causing drowsiness.

Ideal for Daytime Cold and Flu Relief
Best used during the day for managing cold and flu symptoms while staying active.

Quick and Effective Relief Praised
Customers appreciate the fast-acting relief and easy-to-swallow softgels.
Key specs
- active ingredient:acetaminophen, dextromethorphan, phenylephrine
- symptom relief:headache, fever, sore throat
- form:LiquiCaps
- flavor:N/A
- dosage:N/A
8.6

Very Good

Our Rating

9.3
simple to consume

9.3
Flavor

9.1
worth the money
10

Amazon Basic Care
Amazon Basic Care Nighttime Cold and Flu Relief Softgels, 6 Hour Cold Medicine, Relieves Major Flu Symptoms So You Can Rest, 48 Count (Pack of 1)
Main highlights

Powerful Nighttime Relief
This cold and flu medicine provides multi-symptom relief of common cold and flu symptoms while you sleep, including pain, fever, cough, and runny nose.

Ideal for Online Purchase
Convenient for those who prefer not to go out when sick. Works effectively and is cost-efficient compared to name brands.

Effective and Affordable
Customers appreciate the effective relief comparable to name brands at a lower cost, with fast delivery being a significant advantage.
Key specs
- active ingredient:acetaminophen, dextromethorphan, doxylamine
- symptom relief:cold, flu, cough
- form:N/A
- flavor:N/A
- dosage:N/A
8.4

Good

Our Rating

9.9
worth the money

9.3
pain management

8.7
simple to consume

10 Best cold and flus of 2025

1

Vicks DayQuil & NyQuil Ultra Concentrated Liquicaps Co-Pack, Cold & Flu Medicine, Powerful Multi-Symptom Daytime & Nighttime Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, & Cough, 96ct

How do we rank?

How do we rank?

Analyzing top stores

2

Boiron Oscillococcinum Natural Relief for Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

9.7

9.7

9.7

3

Tylenol Cold + Flu Severe Day & Night Caplets for Fever, Pain, Cough & Congestion Relief, 24 Count

4

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

9.3

9.3

9.1

5

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

6

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

9.3

9.1

7

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

9.3

9.1

8.7

8

Mucinex Fast-Max Liquid Gels for Day/Night Cold and Flu, 24 Count

9.7

9.5

8.0

9

Amazon Basic Care Daytime Cold and Flu Relief Liquid Caps Softgel, Non-Drowsy Cold Medicine, Relief of Pain, Fever, Cough, Sore Throat, Nasal Congestion, 48 Count

9.3

9.3

9.1

10

Amazon Basic Care Nighttime Cold and Flu Relief Softgels, 6 Hour Cold Medicine, Relieves Major Flu Symptoms So You Can Rest, 48 Count (Pack of 1)

9.9

9.3

8.7

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