10 Best cold and flus of 2025

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Best Choice

1

Boiron
Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

20% Off
Main highlights

Comprehensive Flu Symptom Relief
Oscillococcinum helps relieve fatigue, headache, body aches, chills, and fever safely for ages 2 and up.

Ideal for Early Flu Onset
Best used at the first sign of flu-like symptoms to reduce duration and severity.

Customer Praised Quick Dissolving
Sweet-tasting pellets dissolve easily under the tongue, praised for convenience.
Key specs
- flavor:Sweet-tasting
- form:Pellets
- symptom relief:Fatigue, headache, body aches
- dosage:At first sign of flu
- active ingredient:Oscillococcinum
9.7

Exceptional

Our Rating

9.7
simple to consume

9.7
Simple to use

9.7
Flavor
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Value for Money

2

Vicks
VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps
Main highlights

Powerful 9-Symptom Relief
Vicks DayQuil and NyQuil Severe provide maximum strength relief for 9 common cold and flu symptoms.

Day and Night Use
Ideal for daytime use with DayQuil's non-drowsy formula and nighttime relief with NyQuil for restful sleep.

Quick Symptom Relief
Customers praise the fast-acting nature, clearing congestion in 10-15 minutes.
9.5

Excellent

Our Rating

8.9
Flavor

8.7
simple to consume

8.2
worth the money
3

Amazon Basic Care
Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)
Main highlights

Multi-Symptom Relief
Provides effective relief from headache, fever, sore throat, and more.

Day and Night Use
Ideal for continuous relief of cold and flu symptoms.

Quick Action
Praised for fast-acting relief within a few hours.
9.4

Excellent

Our Rating

9.3
simple to consume

9.3
Flavor

9.1
worth the money
4

Amazon Basic Care
Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count
Main highlights

Maximum Strength Multi-Symptom Relief
Provides around-the-clock relief for cold and flu symptoms with a combination of daytime and nighttime caplets.

Ideal for Families and Busy Individuals
Perfect for those needing effective relief during the day and restful sleep at night.

Highly Praised Nighttime Formula
Customers appreciate the nighttime caplets for aiding sleep and symptom relief.
Key specs
- flavor:Vapor Ice
- form:Coated caplets
- symptom relief:Cold and flu symptoms
- dosage:N/A
- active ingredient:Compare to Vicks DayQuil/NyQuil
9.2

Excellent

Our Rating

9.3
simple to consume

9.1
worth the money

8.7
Flavor
5

Tylenol
Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

28% Off
Main highlights

Comprehensive Symptom Relief
Relieves fever, pain, congestion, cough, and loosens mucus.

Ideal for Cold and Flu
Perfect for adults and children 12+ with cold and flu symptoms.

Praised Effectiveness
Customers appreciate its superior efficacy over generic alternatives.
9.1

Excellent

Our Rating

9.9
pain management

9.3
worth the money

8.7
simple to consume
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6

Amazon Basic Care
Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

21% Off
Main highlights

Multi-Symptom Relief
Combines pain relief, cough suppressant, and antihistamine for comprehensive cold and flu care.

Nighttime Use
Ideal for nighttime relief, helping you rest and recover.

Sleep Aid Effectiveness
Praised for its fast-acting sleep-inducing properties.
8.9

Very Good

Our Rating

9.3
worth the money

9.1
Flavor
7

Tylenol
Tylenol Cold + Flu Severe Day & Night Caplets Combo Pack for Multi-Symptom Cold & Flu Symptom Relief, Cough, Sore Throat, and Headache Relief, Acetaminophen Pain Reliever, 24 ct

27% Off
Main highlights

Comprehensive Cold Flu Relief
24-count pack offers multi-symptom relief for cold and flu.

Day Night Usage
Ideal for day and night relief with separate formulas.

Highly Praised Value
Customers appreciate the value and effectiveness of the product.
Key specs
- features:Cold & flu relief
- product dimensions:4.52 x 0.78 x 2.95 inches
- active ingredients:Acetaminophen, Phenylephrine HCl
- decongestant:Phenylephrine HCl
- saline solution:N/A
8.7

Very Good

Our Rating
8

Amazon Basic Care

Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Medicine, Combo Pack, Liquid Medication for Day and Night, Original and Berry, 24 fl oz (Pack of 1)

15% Off
8.5

Good

Our Rating

9.1
worth the money

9.1
Comfort

8.4
Flavor
9

ALKA-SELTZER PLUS
Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat 24 Count, Packaging May Vary

21% Off
Main highlights

Fast Relief Formula
Provides liquid fast relief for cold and flu symptoms.

On-the-Go Convenience
Ideal for busy individuals needing quick, portable relief.

Effective Nausea Relief
Effervescence praised for alleviating nausea effectively.
Key specs
- flavor:Citrus
- form:Effervescent
- symptom relief:Cold & Flu
- dosage:10 Sachets
- active ingredient:N/A
8.4

Good

Our Rating
10

Nature's Way
Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

20% Off
Main highlights

Symptom Relief Formula
Natures Way Umcka Cold & Flu Relief offers multi-symptom relief for body aches, congestion, cough, fever, runny nose, and sore throat.

Effective for Quick Recovery
Ideal for reducing cold and flu duration and severity, even when taken after symptoms start.

Great Taste and Easy Use
Customers praise its delicious berry flavor and convenient chewable form.
8.3

Good

Our Rating

9.7
Flavor

8.9
worth the money

10 Best cold and flus of 2025

1

Boiron Oscillococcinum for Relief from Flu-Like Symptoms of Body Aches, Headache, Fever, Chills, and Fatigue - 30 Doses

9.7

9.7

9.7

How do we rank?

How do we rank?

Analyzing top stores

2

VICKS DayQuil & NyQuil SEVERE Co-Pack, Cold & Flu Medicine, Powerful Relief for Headache, Fever, Sore Throat, Minor Aches & Pains, Congestion, Sinus Pressure, Stuffy Nose, and Cough, 48 LiquiCaps

8.9

8.7

8.2

3

Amazon Basic Care Cold and Flu Relief, Daytime and Nighttime Combo Pack Softgels, Powerful Cold Medicine for Day and Night Multi-Symptom Relief, 48 Count(Pack of 1)

9.3

9.3

9.1

4

Amazon Basic Care Vapor Ice Day and Night Severe Cold and Flu Relief Caplets, Maximum Strength Medicine, Combo Pack, 48 Count

9.3

9.1

8.7

5

Tylenol Cold + Flu Severe Medicine Caplets for Fever, Pain, Cough & Congestion, 24 ct.

9.9

9.3

8.7

6

Amazon Basic Care Night Time Cold & Flu Liquid, Cherry, 12 fl oz (Pack of 1)

9.3

9.1

7

Tylenol Cold + Flu Severe Day & Night Caplets Combo Pack for Multi-Symptom Cold & Flu Symptom Relief, Cough, Sore Throat, and Headache Relief, Acetaminophen Pain Reliever, 24 ct

8

Amazon Basic Care Daytime and Nighttime Max Strength Severe Cold and Flu Relief Medicine, Combo Pack, Liquid Medication for Day and Night, Original and Berry, 24 fl oz (Pack of 1)

9.1

9.1

8.4

9

Alka-Seltzer Plus Severe, Cold & Flu Medicine, Citrus Effervescent Tablets, Nasal & Sinus Congestion, Sneezing, Runny Nose, Cough, Sore Throat 24 Count, Packaging May Vary

10

Nature's Way Cold+Flu Relief, Umcka, Shortens Duration and Reduces Severity, Multi-Symptom Relief, Homeopathic, Phenylephrine Free, Non-Drowsy, Berry Flavored, 20 Chewable Tablets (Packaging May Vary)

9.7

8.9

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