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10 Best canker sore medicines of 2025

Save up to 27% off
  • Best Choice

    1

    Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2
    Abreva

    Abreva 10 Percent Docosanol Cold Sore Treatment, Treats Your Fever Blister in 2.5 Days - 0.07 oz Tube x 2

    20% Off
    • active ingredients:10% docosanol
    • application:Portable tube
    • usage:Cold sore treatment
    • weight:1.76 ounces
    • formula:Docosanol cream
    9.9
    Exceptional
    Our Rating
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  • Value for Money

    2

    DenTek Canker Relief Patches for Canker Sore Pain Relief, Helps Relieve Soreness from Braces & Oral Wounds, 6 Count
    DenTek

    DenTek Canker Relief Patches for Canker Sore Pain Relief, Helps Relieve Soreness from Braces & Oral Wounds, 6 Count

    9.8
    Exceptional
    Our Rating

  • 3

    Zilactin-B Fast Acting Canker Sore Treatment - Long Lasting Protection and Oral Pain Relief of Canker Sores, Mouth Sores and Gum Irritations, Made in USA, 0.25oz Gel, Pack of 1
    Zilactin

    Zilactin-B Fast Acting Canker Sore Treatment - Long Lasting Protection and Oral Pain Relief of Canker Sores, Mouth Sores and Gum Irritations, Made in USA, 0.25oz Gel, Pack of 1

    • Pain Relief:Immediate, long lasting
    • Active Ingredients:10% Benzocaine
    • Application Method:Bioadhesive technology
    • Formulation:Proprietary blend
    • Target Area:Mouth, gums
    9.6
    Exceptional

  • 4

    Orajel 3X for Mouth Sores: Maximum Strength Gel Tube 0.42oz- From #1 Oral Pain Relief Brand
    Orajel

    Orajel 3X for Mouth Sores: Maximum Strength Gel Tube 0.42oz- From #1 Oral Pain Relief Brand

    27% Off
    • Pain Relief:Instant pain relief
    • Active Ingredients:20% Benzocaine
    • Application Method:Gel
    • Formulation:Maximum strength gel
    • Target Area:Mouth
    9.4
    Excellent
    Our Rating

  • 5

    Canker-X Mouth Sore Gel, Fast Pain Relief & Healing for Canker Sores, Cheek Bites and Oral Abrasions, Oral Pain Relief Gel, Benzocaine-Free and Alcohol-Free, Adults and Kids 6+ Years, 0.28 fl oz
    Canker-X

    Canker-X Mouth Sore Gel, Fast Pain Relief & Healing for Canker Sores, Cheek Bites and Oral Abrasions, Oral Pain Relief Gel, Benzocaine-Free and Alcohol-Free, Adults and Kids 6+ Years, 0.28 fl oz

    • Pain Relief:Fast, long-lasting
    • Active Ingredients:Aloe Vera, Sodium Hyaluronate
    • Application Method:Extended nozzle, finger, swab
    • Formulation:Gel
    • Target Area:Mouth sores
    9.1
    Excellent
    Our Rating
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  • 6

    Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)
    Anbesol

    Anbesol Maximum Strength Oral Pain Relief Gel, Instant Pain Relief For Toothache Pain, Canker Sores, Sore Gums, Mouth Sores, Denture Pain, and Aligner Pain, ADA Accepted, 0.33 oz (packaging may vary)

    15% Off
    9.0
    Excellent
    Our Rating

  • 7

    Dentemp Canker Cover - Canker Sore Medicine Pain Reliever (8 Count) - Canker Sore Treatment to Relieve Canker Pain, Mouth Sores & Mouth Irritation - Fast Acting Canker Sore Relief Tablets for Adults
    Dentemp

    Dentemp Canker Cover - Canker Sore Medicine Pain Reliever (8 Count) - Canker Sore Treatment to Relieve Canker Pain, Mouth Sores & Mouth Irritation - Fast Acting Canker Sore Relief Tablets for Adults

    • Pain Relief:Immediate pain relief
    • Active Ingredients:Menthol
    • Application Method:Place on sore
    • Formulation:Mint-flavored patches
    • Target Area:Inside the mouth
    8.9
    Very Good

  • 8

    Anbesol Maximum Strength Liquid, Instant Oral Pain Relief For Toothaches, Mouth Sores*, Gum, Braces & Denture Pain, ADA Accepted, 0.41 oz
    Anbesol

    Anbesol Maximum Strength Liquid, Instant Oral Pain Relief For Toothaches, Mouth Sores*, Gum, Braces & Denture Pain, ADA Accepted, 0.41 oz

    17% Off
    • Pain Relief:Instant Oral Pain Relief
    • Active Ingredients:Benzocaine
    • Application Method:Apply directly
    • Formulation:Liquid Formula
    • Target Area:Mouth
    8.8
    Very Good

  • 9

    Kank-A Triple Action Gel, 0.42 oz, Maximum Strength Mouth Pain Relief Gel for Canker Sores, Triple Action Treatment, Fast Acting and Long-Lasting Pain Relief, Cools and Soothes Irritation, 0.42 oz
    Kank-A

    Kank-A Triple Action Gel, 0.42 oz, Maximum Strength Mouth Pain Relief Gel for Canker Sores, Triple Action Treatment, Fast Acting and Long-Lasting Pain Relief, Cools and Soothes Irritation, 0.42 oz

    8.6
    Very Good

  • 10

    Prevention Mouth Sore Mouth Rinse, Canker Sore Treatment, Oral Pain Relief Mouthwash for Ulcers and Sores, Braces, with Hydrogen Peroxide, Alcohol-Free, Fluoride Free, 16 oz, Soothing Mint, 1 Pack
    PHS Brands

    Prevention Mouth Sore Mouth Rinse, Canker Sore Treatment, Oral Pain Relief Mouthwash for Ulcers and Sores, Braces, with Hydrogen Peroxide, Alcohol-Free, Fluoride Free, 16 oz, Soothing Mint, 1 Pack

    • Active Ingredients:Hydrogen peroxide, sodium citrate
    • Usage:Rinse 3-5 times daily
    • Flavors:Mint
    • Dimensions:9.09 x 5.43 x 5.35 inches
    • Alcohol Free:Yes
    8.4
    Good
    Our Rating