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10 Best oral pain relief medications of 2026

Save up to 27% off
  • Best Choice

    1

    Orajel 4X Toothache and Gum Pain Medicated Pain Relief Cream, 0.33 Oz
    Orajel
    9.9
    Exceptional

    Orajel 4X Toothache and Gum Pain Medicated Pain Relief Cream, 0.33 Oz

    25% Off
    • asin:B08CBQ59CB
    • product dimensions:4.38 x 1 x 3.69 inches 0.34 ounces
    • date first available:July 2, 2020
    • item model number:Orajel, orajel, toothache
    • manufacturer:Church & Dwight - Personal Care
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  • Value for Money

    2

    DenTek Instant Oral Pain Relief Kit with Benzocaine, 50 Treatments
    DenTek
    9.7
    Exceptional

    DenTek Instant Oral Pain Relief Kit with Benzocaine, 50 Treatments

    15% Off
    • is discontinued by manufacturer:No
    • product dimensions:3.95 x 1.19 x 4.03 inches 2.12 ounces
    • country of origin:USA
    • asin:B00JAD7YD4
    • date first available:March 27, 2014

  • 3

    Orajel 3X Mouth Sores Medicated Pain Relief Gel, Extra Strength, 0.42 Oz
    Orajel
    9.6
    Exceptional

    Orajel 3X Mouth Sores Medicated Pain Relief Gel, Extra Strength, 0.42 Oz

    27% Off

  • 4

    Orajel 2X Medicated Toothache & Mouth Sores Liquid, 0.45 Fl Oz
    Orajel
    9.5
    Excellent

    Orajel 2X Medicated Toothache & Mouth Sores Liquid, 0.45 Fl Oz

    • asin:B00A6VAV8O
    • product dimensions:6 x 4 x 4 inches 1.76 ounces
    • date first available:February 11, 2011
    • item model number:7138Q
    • manufacturer:Church & Dwight

  • 5

    Benzodent Maximum Strength Dental and Oral Pain Relieving Cream for Dentures, Mouth Sores, and Braces, Long lasting Topical Anesthetic, 0.25 oz
    Benzodent
    9.3
    Excellent

    Benzodent Maximum Strength Dental and Oral Pain Relieving Cream for Dentures, Mouth Sores, and Braces, Long lasting Topical Anesthetic, 0.25 oz

    • asin:B01MTDQXM5
    • product dimensions:3.75 x 1.06 x 3.13 inches; 0.25 ounces
    • date first available:January 20, 2017
    • item model number:10532-A
    • manufacturer:EMCW9
  • See Today’s Deals & Prices

  • 6

    Safetec Oral Pain Relief, .75 g Packets, Box of 144
    Safetec
    9.1
    Excellent

    Safetec Oral Pain Relief, .75 g Packets, Box of 144

    11% Off

  • 7

    Orajel Mouth Sore Medicated Rinse for Oral Pain Relief, Mint, 16 Oz, 3-Pack
    Orajel
    8.9
    Very Good

    Orajel Mouth Sore Medicated Rinse for Oral Pain Relief, Mint, 16 Oz, 3-Pack

    27% Off

  • 8

    Zilactin B Fast Acting Canker Sore Treatment Gel 0.25 Oz, Pack of 1
    Zilactin
    8.7
    Very Good

    Zilactin B Fast Acting Canker Sore Treatment Gel 0.25 Oz, Pack of 1

    • asin:B0D642ZD22
    • product dimensions:3.5 x 0.9 x 3.5 inches; 0.25 ounces
    • date first available:June 4, 2024
    • item model number:N/A
    • manufacturer:Ascent Consumer Products, Inc.

  • 9

    Oral Analgesic Gel – Fast Numbing Oral Pain Relief for Toothaches, Canker Sores, Sore Gums, Mouth Sores, Denture & Cheek Bite – 0.42 OZ (Pack of 1)
    Generic
    8.6
    Very Good

    Oral Analgesic Gel – Fast Numbing Oral Pain Relief for Toothaches, Canker Sores, Sore Gums, Mouth Sores, Denture & Cheek Bite – 0.42 OZ (Pack of 1)

  • 10

    Orajel 3X Toothache and Gum Pain Medicated Pain Relief Gel, 0.42 Oz
    Orajel
    8.3
    Good

    Orajel 3X Toothache and Gum Pain Medicated Pain Relief Gel, 0.42 Oz