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10 Best otc dog flea treatments of 2025

Save up to 14% off
  • Best Choice

    1

    Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Medium, Fast Acting Waterproof Topical Drops, 6 Month Supply
    Advecta

    Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Medium, Fast Acting Waterproof Topical Drops, 6 Month Supply

    • Active Ingredients:imidacloprid, permethrin, pyriproxyfen
    • Application Method:Topical
    • Protection Type:Fleas, ticks, mosquitoes
    • Flavor:Fragrance-free
    • Target Weight:N/A
    9.6
    Exceptional
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  • Value for Money

    2

    NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses
    NEXTSTAR

    NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses

    9.4
    Excellent

  • 3

    Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
    Woyamay

    Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes

    • Active Ingredients:Coconut oil, flaxseed, yeast
    • Application Method:Oral chews
    • Protection Type:Flea and tick prevention
    • Flavor:Chicken
    • Target Weight:Small, medium, large dogs
    9.3
    Excellent

  • 4

    FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
    Frontline

    FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

    11% Off
    9.2
    Excellent
    Our Rating

  • 5

    PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses (Pack of 1) (Packaging May Vary)
    PetArmor

    PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Dogs, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Dogs Over 25 lbs, 6 Doses (Pack of 1) (Packaging May Vary)

    9.1
    Excellent
    Our Rating
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  • 6

    PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large Dogs (45-88 lbs)
    PetArmor

    PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 3 Doses, Waterproof Topical, Fast Acting, Large Dogs (45-88 lbs)

    14% Off
    8.8
    Very Good
    Our Rating

  • 7

    FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments
    FRONTLINE

    FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

    11% Off
    8.5
    Good
    Our Rating

  • 8

    TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Medium Dogs 11-20 lbs | Topical Drops | 4 Months Flea Treatment
    TevraPet

    TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Medium Dogs 11-20 lbs | Topical Drops | 4 Months Flea Treatment

    8.4
    Good
    Our Rating

  • 9

    Dog Flea and Tick Treatment Chewable 200 Treatment Chews Natural Soft Chew Fleas Ticks Treatment Dog Oral Chewables Support Supplement Pest Defense Breeds and Ages Dogs Chicken Flavor
    TTLXBL

    Dog Flea and Tick Treatment Chewable 200 Treatment Chews Natural Soft Chew Fleas Ticks Treatment Dog Oral Chewables Support Supplement Pest Defense Breeds and Ages Dogs Chicken Flavor

    8.3
    Good

  • 10

    FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments
    Frontline

    FRONTLINE Plus Flea and Tick Treatment for Medium Dogs Up to 23 to 44 lbs. 3 Treatments

    11% Off
    8.2
    Good
    Our Rating

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