10 Best flea and tick drops for dogs of 2025

Save up to 21% off

Best Choice

1

Advecta
Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Medium, Fast Acting Waterproof Topical Drops, 6 Month Supply
Main highlights

Kills and Repels Fleas
ADVECTA Ultra for Dogs kills and repels fleas, ticks, and mosquitoes without needing a bite, ensuring your pet's comfort and safety.

Ideal for Active Dogs
Perfect for dogs that swim or get wet, as the formula remains effective and waterproof after 24 hours.

Highly Effective Flea Cycle Control
Customers praise its ability to break the flea life cycle by targeting adult fleas, eggs, and larvae, preventing reinfestation.
Key specs
- Active Ingredients:imidacloprid, permethrin, pyriproxyfen
- Application Method:Topical
- Protection Type:Fleas, ticks, mosquitoes
- Flavor:Fragrance-free
- Target Weight:N/A
9.6

Exceptional

Our Rating
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Value for Money

2

NEXTSTAR

NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses
9.4

Excellent

Our Rating
3

Woyamay
Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
Main highlights

Natural Ingredients and Long-Term Protection
Made with natural ingredients, provides over 3 months of flea and tick prevention.

Ideal for All Dog Sizes and Ages
Suitable for small, medium, and large dogs, including puppies and seniors.

Delicious Flavor Enhances Compliance
Chicken flavor loved by dogs, making it easy to administer.
Key specs
- Active Ingredients:Coconut oil, flaxseed, yeast
- Application Method:Oral chews
- Protection Type:Flea and tick prevention
- Flavor:Chicken
- Target Weight:Small, medium, large dogs
9.3

Excellent

Our Rating
4

FRONTLINE
FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

11% Off
Main highlights

Long-Lasting Protection
FRONTLINE Plus offers month-long protection against fleas, ticks, and lice with waterproof, fast-acting formula.

Ideal for Small Dogs
Perfect for dogs 5-22 lbs, ensuring safe and effective flea and tick control.

Highly Effective
Praised for consistent month-long effectiveness, even in challenging environments.
9.0

Excellent

Our Rating

8.2
Simple to take off

8.0
Simple to use

8.0
Aroma
5

MaxBuddy
Flea and Tick Oral Prevention Support & Treatment for Dogs and Cats – Natural Flea Control with Multivitamin - Supplement Drops for Small and Large Dogs – Made in The USA

20% Off
Main highlights

Comprehensive Flea Tick Protection
Offers daily defense against fleas, ticks, eggs, larvae, and mosquitoes.

Ideal for All Pet Sizes
Perfect for puppies, kittens, and adult pets of any size.

Highly Praised Health Benefits
Customers love the added multivitamins and enzymes for joint and immune support.
8.8

Very Good

Our Rating
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6

TevraPet
Activate II Flea and Tick Prevention for Dogs | 4 Count | Large Dogs 21-55 lbs | Topical Drops | 4 Months Flea Treatment
Main highlights

Fast Acting Flea and Tick Protection
Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen to repel and kill fleas and ticks on contact.

Ideal for Outdoor Dogs
Perfect for dogs frequently exposed to fleas and ticks, especially in areas with high deer populations.

Affordable and Effective
Praised for its reasonable cost and effectiveness in reducing flea and tick infestations.
8.7

Very Good

Our Rating

8.2
Simple to use

8.0
worth the money

8.0
Aroma
7

PetArmor
PetArmor for Dogs, Flea and Tick Treatment for Large Dogs (45-88 Pounds), Includes 3 Month Supply of Topical Flea Treatments

21% Off
Main highlights

Effective Flea and Tick Protection
PetArmor for Dogs offers vet-quality flea and tick prevention, utilizing fipronil to eliminate adult fleas, ticks, and lice.

Ideal for Large Dogs
Designed for dogs weighing 45-88 pounds, perfect for large breeds.

Affordable and Easy Application
Customers praise its affordability and straightforward application process.
8.6

Very Good

Our Rating

9.9
Comfort

8.4
Simple to use

8.0
Aroma
8

Amazon Basics
Amazon Basics Flea and Tick Topical Treatment for Small Dogs (5-22 pounds), 3 Count (Previously Solimo)
Main highlights

Long-Lasting Protection
Provides up to 30 days of flea and tick prevention.

Ideal for Small Dogs
Perfect for small dogs weighing 5-22 pounds.

Easy Application Praised
Users appreciate the easy and quick application process.
8.5

Good

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Comfort
9

Hartz
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

16% Off
Main highlights

Effective Flea and Tick Protection
Topical formula kills fleas and deer ticks; includes 3 monthly treatments.

Ideal for Cats and Kittens
Suitable for cats and kittens 12 weeks and older, weighing 5 pounds and over.

Highly Praised for Effectiveness
Customers appreciate its effectiveness in preventing fleas and ticks.
8.2

Good

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
Aroma
10

K9 Advantix
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply
Main highlights

Quick and Effective Protection
Kills fleas within 12 hours and repels ticks, mosquitoes, and more.

Ideal for Medium-Sized Dogs
Perfect for dogs weighing 11-20 lbs needing comprehensive pest protection.

Customer Satisfaction with Immediate Results
Highly praised for effectively stopping dogs from scratching.
8.0

Good

Our Rating

8.4
Simple to use

8.0
worth the money

8.0
Aroma

10 Best flea and tick drops for dogs of 2025

1

Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Medium, Fast Acting Waterproof Topical Drops, 6 Month Supply

How do we rank?

How do we rank?

Analyzing top stores

2

NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses

3

Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes

4

FRONTLINE Plus Flea and Tick Treatment for Small Dogs Upto 5 to 22 lbs. 3 Treatments

8.2

8.0

8.0

5

Flea and Tick Oral Prevention Support & Treatment for Dogs and Cats – Natural Flea Control with Multivitamin - Supplement Drops for Small and Large Dogs – Made in The USA

6

Activate II Flea and Tick Prevention for Dogs | 4 Count | Large Dogs 21-55 lbs | Topical Drops | 4 Months Flea Treatment

8.2

8.0

8.0

7

PetArmor for Dogs, Flea and Tick Treatment for Large Dogs (45-88 Pounds), Includes 3 Month Supply of Topical Flea Treatments

9.9

8.4

8.0

8

Amazon Basics Flea and Tick Topical Treatment for Small Dogs (5-22 pounds), 3 Count (Previously Solimo)

8.0

8.0

8.0

9

Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

8.0

8.0

8.0

10

K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply

8.4

8.0

8.0

Similar products on Amazon

Sergeant's Guardian Flea & Tick Squeeze On for Dogs 7-33 lbs., 3 Count

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