9 Best cat flea treatments of 2025

Save up to 31% off

Best Choice

1

Frontline
FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

22% Off
Main highlights

Waterproof Long-Lasting Protection
Frontline Plus offers waterproof, fast-acting flea and tick control for cats over 1.5 lbs.

Ideal for Infestation Prevention
Perfect for preventing flea infestations and protecting against Lyme disease transmission.

Veterinarian Trusted
Praised for its effectiveness and long-standing trust among veterinarians.
9.7

Exceptional

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Simple to take off
How do we rank?

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Careful review Our team ensures quality, value, and fit based on real user feedback

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Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
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Value for Money

2

ProElobara
Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply
Main highlights

Fast-Acting and Long-Lasting Protection
Provides up to 30 days of continuous protection against fleas and ticks.

Ideal for Cats with Sensitive Skin
Safe and gentle formula suitable for all cats, including kittens and seniors.

Easy to Apply
Topical treatment applied to shoulder blades, praised for ease of use.
9.6

Exceptional

Our Rating
3

Amazon Basics
Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)
Main highlights

Fast-Acting Protection
Begins eliminating fleas and ticks within 24 hours.

Ideal for Multi-Cat Households
Provides six doses, perfect for homes with multiple cats.

High Customer Satisfaction
Praised for affordability and effectiveness in eliminating fleas.
9.5

Excellent

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Comfort
4

Advantage
Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 1-Month Supply
Main highlights

Comprehensive Flea Protection
Advantage II Large Cat kills adult fleas, larvae, and eggs.

Ideal for Large Cats
Perfect for cats over 9 lbs., aged 8 weeks or older.

Fast-Acting Formula
Praised for quick effectiveness, killing fleas within 12 hours.
9.3

Excellent

Our Rating

8.9
Simple to use

8.0
Aroma

8.0
worth the money
5

Amazon Basics
Amazon Basics Flea Topical for Large Cats (over 9 pounds), 4 Count (Previously Solimo)

31% Off
Main highlights

Quick Flea Elimination
Amazon Basics Flea Topical starts eliminating fleas within 12 hours.

Ideal for Large Cats
Perfect for cats over 9 pounds, offering effective flea control.

Customer Satisfaction Guarantee
Customers appreciate its effectiveness and affordability compared to name brands.
9.2

Excellent

Our Rating

8.2
Simple to use

8.0
Aroma

8.0
worth the money
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6

Advantage
Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 1-Month Supply
Main highlights

Total Flea Protection
Advantage II kills adult fleas, larvae, and eggs on contact.

Ideal for Small Cats
Perfect for cats weighing 5-9 lbs, aged 8 weeks+.

Fast Acting Relief
Customers appreciate its effectiveness within 12 hours.
9.1

Excellent

Our Rating

8.7
Simple to use

8.0
Aroma

8.0
Comfort
7

Hartz
Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

16% Off
Main highlights

Effective Flea and Tick Protection
Topical formula kills fleas and deer ticks; includes 3 monthly treatments.

Ideal for Cats and Kittens
Suitable for cats and kittens 12 weeks and older, weighing 5 pounds and over.

Highly Praised for Effectiveness
Customers appreciate its effectiveness in preventing fleas and ticks.
8.8

Very Good

Our Rating

8.0
Simple to use

8.0
worth the money

8.0
Aroma
8

Amazon Basics
Amazon Basics Topical Flea Treatment for Medium Cats (5-9 Pounds), 4 Count (Previously Solimo)

31% Off
Main highlights

Fast Flea Elimination
Begins killing fleas within 12 hours, providing quick relief.

Ideal for Small Cats
Perfect for cats weighing 5-9 pounds, ensuring safe use.

Customer Praised Effectiveness
Highly effective in keeping cats flea-free for 30 days.
8.6

Very Good

Our Rating

8.2
Comfort

8.0
Simple to use

8.0
worth the money
9

PetArmor
PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses
Main highlights

Fast-Acting Flea Treatment
Begins killing fleas within 30 minutes of administration.

Versatile for Cat Sizes
Suitable for cats weighing 2 to 25 pounds.

Proven Customer Satisfaction
Highly praised for visible flea reduction and ease of use.
8.5

Good

Our Rating

8.4
Simple to use

8.0
Comfort

8.0
worth the money

9 Best cat flea treatments of 2025

1

FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

8.0

8.0

8.0

How do we rank?

How do we rank?

Analyzing top stores

2

Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply

3

Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

8.0

8.0

8.0

4

Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 1-Month Supply

8.9

8.0

8.0

5

Amazon Basics Flea Topical for Large Cats (over 9 pounds), 4 Count (Previously Solimo)

8.2

8.0

8.0

6

Advantage II Small Cat Vet-Recommended Flea Treatment & Prevention | Cats 5-9 lbs. | 1-Month Supply

8.7

8.0

8.0

7

Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

8.0

8.0

8.0

8

Amazon Basics Topical Flea Treatment for Medium Cats (5-9 Pounds), 4 Count (Previously Solimo)

8.2

8.0

8.0

9

PetArmor CAPACTION (nitenpyram) Oral Flea Treatment for Cats, Fast Acting Tablets Start Killing Fleas in 30 Minutes, Cats 2-25 lbs, 6 Doses

8.4

8.0

8.0

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