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10 Best cat flea and tick treatments of 2025

Save up to 22% off
  • Best Choice

    1

    PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 6 Dose, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs
    PetArmor

    PetArmor Plus Flea and Tick Prevention for Cats, Cat Flea and Tick Treatment, 6 Dose, Waterproof Topical, Fast Acting, Cats Over 1.5 lbs

    9.7
    Exceptional
    Our Rating
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  • Value for Money

    2

    FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments
    Frontline

    FRONTLINE Plus Flea and Tick Treatment for Cats Over 1.5 lbs. 3 Treatments

    22% Off
    9.5
    Excellent
    Our Rating

  • 3

    Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)
    Amazon Basics

    Amazon Basics Flea and Tick Topical Treatment for Cats (over 1.5 lbs), 6 Count (Previously Solimo)

    9.4
    Excellent
    Our Rating

  • 4

    Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply
    ProElobara

    Flea and Tick Prevention for Cats & Kittens: Waterproof Topical Cat Flea and Tick Treatment – Fast-Acting & Long-Lasting At Home Flea Control for Cats Over 1.5 lbs and 8 Weeks or Older – 6-Dose Supply

    9.3
    Excellent

  • 5

    Amazon Basics Flea Topical for Large Cats (over 9 pounds), 4 Count (Previously Solimo)
    Amazon Basics

    Amazon Basics Flea Topical for Large Cats (over 9 pounds), 4 Count (Previously Solimo)

    9.2
    Excellent
    Our Rating
  • See Today’s Deals & Prices

  • 6

    Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments
    Hartz

    Hartz UltraGuard Topical Flea & Tick Prevention for Cats and Kittens - 3 Monthly Treatments

    16% Off
    8.9
    Very Good
    Our Rating

  • 7

    Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 1-Month Supply
    Advantage

    Advantage II Large Cat Vet-Recommended Flea Treatment & Prevention | Cats Over 9 lbs. | 1-Month Supply

    8.7
    Very Good
    Our Rating

  • 8

    TevraPet FirstAct Plus Flea and Tick Topical for Cats over 1.5lbs, 3 Dose Waterproof Flea and Tick Control/Prevention for 3 Months
    TevraPet

    TevraPet FirstAct Plus Flea and Tick Topical for Cats over 1.5lbs, 3 Dose Waterproof Flea and Tick Control/Prevention for 3 Months

    8.6
    Very Good
    Our Rating

  • 9

    Amazon Basics Topical Flea Treatment for Medium Cats (5-9 Pounds), 4 Count (Previously Solimo)
    Amazon Basics

    Amazon Basics Topical Flea Treatment for Medium Cats (5-9 Pounds), 4 Count (Previously Solimo)

    8.4
    Good
    Our Rating

  • 10

    TevraPet Actispot II Flea Treatment for Small and Medium Cats 5-9 lbs | 6 Doses | Powerful Prevention and Control, Clear
    TevraPet

    TevraPet Actispot II Flea Treatment for Small and Medium Cats 5-9 lbs | 6 Doses | Powerful Prevention and Control, Clear

    10% Off
    8.3
    Good
    Our Rating