10 Best dog heartworm prevention non prescriptions of 2025

Save up to 34% off

Best Choice

1

PetSilver
PetSilver Immune Support, Natural Nebulizer Solution, Promotes Respiratory Health in Cats & Dogs, Allergies, Sinus & Cough Treatment, Easy to Use, Patented Chelated Silver, Made in The USA, 16 fl oz
Main highlights

Natural Immune Support
PetSilver Immune Support solution uses natural chelated silver to relieve lung and respiratory inflammation, infection, and irritations while supporting immune defenses.

Versatile Application Methods
Ideal for use in nebulizers or with syringes for pets who can't tolerate nebulizers. Suitable for chronic conditions and can complement veterinary treatments.

Ease of Use
Customers praise the product's ease of use, especially in nebulizers, and its effectiveness in improving respiratory conditions in pets.
9.8

Exceptional

Our Rating

9.9
worth the money

9.9
Simple to use

9.3
Simple to clean
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Value for Money

2

BestLife4Pets

Dog Kennel Cough Treatment & Natural Decongestant, Breathe Easy Cough Treatment for Wheezing, Sneezing, and Nasal Congestion, Supports Respiratory Health and Eases Cold Symptoms, 800 Small Pills
9.6

Exceptional

Our Rating
3

Interceptor

Interceptor Plus Prevention for Heartworm + 4 Other Worms for Dogs 50.1-100 lbs. | 6 Chews, 6-Month Supply
9.5

Excellent

Our Rating
4

K9 Advantix
K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply
Main highlights

30-Day Protection for Dogs 21-55 lbs
K9 Advantix II provides a 30-day treatment and prevention for fleas, ticks, mosquitoes, biting flies, and lice, suitable for dogs weighing 21-55 lbs.

Use Based on Dog's Weight
Ensure to purchase K9 Advantix II according to your dog's weight, not size, for effective flea and tick control. Ideal for suburban and rural areas.

Effective Flea and Tick Repellent
Customers praise K9 Advantix II for its effectiveness in repelling fleas and ticks, with noticeable results within 12 hours and long-lasting protection.
9.3

Excellent

Our Rating

8.7
Simple to use

8.0
Aroma

8.0
worth the money
5

Woyamay
Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
Main highlights

Natural Ingredients and Long-Term Protection
Made with natural ingredients, provides over 3 months of flea and tick prevention.

Ideal for All Dog Sizes and Ages
Suitable for small, medium, and large dogs, including puppies and seniors.

Delicious Flavor Enhances Compliance
Chicken flavor loved by dogs, making it easy to administer.
9.2

Excellent

Our Rating
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6

TevraPet
TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Medium Dogs 11-20 lbs | Topical Drops | 4 Months Flea Treatment
Main highlights

Fast Acting Protection
Uses Imidacloprid, Permethrin, and Pyriproxyfen for quick flea and tick control.

Ideal for Medium Dogs
Perfect for dogs 11-20 lbs, providing monthly protection.

Customer Praised Affordability
Praised for being cost-effective while maintaining effectiveness.
9.1

Excellent

Our Rating

8.2
Simple to use

8.0
worth the money

8.0
Aroma
7

K9 Advantix
K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply
Main highlights

Quick and Effective Protection
Kills fleas within 12 hours and repels ticks, mosquitoes, and more.

Ideal for Medium-Sized Dogs
Perfect for dogs weighing 11-20 lbs needing comprehensive pest protection.

Customer Satisfaction with Immediate Results
Highly praised for effectively stopping dogs from scratching.
8.9

Very Good

Our Rating

8.4
Simple to use

8.0
worth the money

8.0
Aroma
8

Petsology

Flea and Tick Prevention for Dogs Pills - Natural Dog Flea & Tick Control - 170 Soft Chewables - Oral Defense Treatment for Dogs Supplement - Vet Formulated Chews - All Breeds & Ages - Made in USA

34% Off
8.7

Very Good

Our Rating
9

PetArmor
PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting, Large Dogs Dogs (45-88 lbs)
Main highlights

Comprehensive Flea and Tick Protection
PetArmor Plus offers waterproof flea and tick prevention, killing fleas, eggs, larvae, ticks, and lice for up to 30 days.

Ideal for Large Dogs
Designed for dogs weighing 45-88 pounds, providing six months of effective flea and tick control.

Ease of Use
Customers praise its simple application process, making it hassle-free to keep pets pest-free.
8.6

Very Good

Our Rating

9.3
Water tight

8.2
Simple to use

8.0
Aroma
10

K9 Advantix
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply
Main highlights

Comprehensive Protection
Protects dogs over 55 lbs from fleas, ticks, mosquitoes, biting flies, and lice with a 30-day treatment.

Ideal for Double Coated Breeds
Effective for breeds with dense coats like Siberian Huskies, ensuring thorough pest control.

Fast Acting and Mess-Free
Kills fleas within 12 hours without the need for a bath, praised for ease of use and effectiveness.
8.5

Good

Our Rating

9.9
Aroma

8.7
Simple to use

8.0
Water tight

10 Best dog heartworm prevention non prescriptions of 2025

1

PetSilver Immune Support, Natural Nebulizer Solution, Promotes Respiratory Health in Cats & Dogs, Allergies, Sinus & Cough Treatment, Easy to Use, Patented Chelated Silver, Made in The USA, 16 fl oz

9.9

9.9

9.3

How do we rank?

How do we rank?

Analyzing top stores

2

Dog Kennel Cough Treatment & Natural Decongestant, Breathe Easy Cough Treatment for Wheezing, Sneezing, and Nasal Congestion, Supports Respiratory Health and Eases Cold Symptoms, 800 Small Pills

3

Interceptor Plus Prevention for Heartworm + 4 Other Worms for Dogs 50.1-100 lbs. | 6 Chews, 6-Month Supply

4

K9 Advantix II Large Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 21 - 55 lbs. | 4-Mo Supply

8.7

8.0

8.0

5

Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes

6

TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Medium Dogs 11-20 lbs | Topical Drops | 4 Months Flea Treatment

8.2

8.0

8.0

7

K9 Advantix II Medium Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs 11-20 lbs. | 2-Mo Supply

8.4

8.0

8.0

8

Flea and Tick Prevention for Dogs Pills - Natural Dog Flea & Tick Control - 170 Soft Chewables - Oral Defense Treatment for Dogs Supplement - Vet Formulated Chews - All Breeds & Ages - Made in USA

9

PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting, Large Dogs Dogs (45-88 lbs)

9.3

8.2

8.0

10

K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 2-Mo Supply

9.9

8.7

8.0

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