10 Best dog flea tick worm treatments of 2025

Save up to 11% off

Best Choice

1

Advecta
Advecta Ultra Flea and Tick Prevention for Dogs - Dog and Puppy Treatment and Control - Mosquito Repellent - Medium, Fast Acting Waterproof Topical Drops, 6 Month Supply
Main highlights

Kills and Repels Fleas
ADVECTA Ultra for Dogs kills and repels fleas, ticks, and mosquitoes without needing a bite, ensuring your pet's comfort and safety.

Ideal for Active Dogs
Perfect for dogs that swim or get wet, as the formula remains effective and waterproof after 24 hours.

Highly Effective Flea Cycle Control
Customers praise its ability to break the flea life cycle by targeting adult fleas, eggs, and larvae, preventing reinfestation.
Key specs
- Application Method:Topical
- Protection Type:Fleas, ticks, mosquitoes
- Active Ingredients:imidacloprid, permethrin, pyriproxyfen
- Treatment Duration:N/A
- Flavor:Fragrance-free
9.6

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

NEXTSTAR

NEXTSTAR Flea and Tick Prevention for Dogs, Repellent, and Control, Fast Acting Waterproof Topical Drops for Large Dogs, 6 Monthly Doses
9.4

Excellent

Our Rating
3

Woyamay
Woyamay Flea and Tick Prevention for Dogs Chewables, 200 Soft Treats, Natural Dog Flea and Tick Treatment, Oral Flea Chews for Dogs Supplement, Flea and Tick Chews for Dogs Puppies, All Breeds & Sizes
Main highlights

Natural Ingredients and Long-Term Protection
Made with natural ingredients, provides over 3 months of flea and tick prevention.

Ideal for All Dog Sizes and Ages
Suitable for small, medium, and large dogs, including puppies and seniors.

Delicious Flavor Enhances Compliance
Chicken flavor loved by dogs, making it easy to administer.
Key specs
- Application Method:Oral chews
- Protection Type:Flea and tick prevention
- Active Ingredients:Coconut oil, flaxseed, yeast
- Treatment Duration:Over 3 months
- Flavor:Chicken
9.3

Excellent

Our Rating
4

Frontline
Frontline Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments

11% Off
Main highlights

Comprehensive Flea and Tick Protection
FRONTLINE Plus kills fleas, ticks, larvae, and lice effectively.

Ideal for Large Dogs
Perfect for dogs 45 to 88 lbs., including thick coats.

Waterproof and Long-lasting
Proven waterproof even through creeks and rivers.
9.2

Excellent

Our Rating

8.0
Simple to use

8.0
Aroma

8.0
Comfort
5

PetArmor
PetArmor Plus Flea and Tick Prevention for Dogs, Dog Flea and Tick Treatment, 6 Doses, Waterproof Topical, Fast Acting, Large Dogs Dogs (45-88 lbs)

11% Off
Main highlights

Comprehensive Flea and Tick Protection
PetArmor Plus offers waterproof flea and tick prevention, killing fleas, eggs, larvae, ticks, and lice for up to 30 days.

Ideal for Large Dogs
Designed for dogs weighing 45-88 pounds, providing six months of effective flea and tick control.

Ease of Use
Customers praise its simple application process, making it hassle-free to keep pets pest-free.
Key specs
- Application Method:Topical
- Protection Type:Flea and tick
- Active Ingredients:fipronil, S-methoprene
- Treatment Duration:Up to 30 days
- Flavor:N/A
9.1

Excellent

Our Rating

9.3
Water tight

8.2
Simple to use

8.0
Aroma
See Today’s Deals & Prices
6

TevraPet
TevraPet Activate II Flea and Tick Prevention for Dogs | 4 Count | Extra Large Dogs 55+ lbs | Topical Drops | 4 Months Flea Treatment
Main highlights

Fast Acting Flea and Tick Protection
Activate II uses Imidacloprid, Permethrin, and Pyriproxyfen for quick and effective pest control.

Ideal for Large Dogs
Perfect for extra-large dogs 55+ lbs needing monthly flea and tick prevention.

Easy Application Praised by Users
Customers appreciate the simple application process and effective pest prevention.
9.0

Excellent

Our Rating

8.2
Simple to use

8.0
worth the money

8.0
Aroma
7

K9 Advantix
K9 Advantix II XL Dog Vet-Recommended Flea, Tick & Mosquito Treatment & Prevention | Dogs Over 55 lbs. | 1-Mo Supply
Main highlights

Comprehensive Protection
Protects dogs over 55 lbs from fleas, ticks, mosquitoes, biting flies, and lice with a 30-day treatment.

Ideal for Large Breeds
Perfect for large dogs needing effective flea and tick prevention without a prescription.

Quick Flea Elimination
Kills fleas within 12 hours of application, praised for fast effectiveness.
8.9

Very Good

Our Rating

8.7
Simple to use

8.0
Water tight

8.0
worth the money
8

Amazon Basics
Amazon Brand - Solimo for Dogs Large Dog (45-88 pounds) Flea and Tick Treatment, 6 Doses
Main highlights

Fast-Acting Protection
Starts eliminating fleas and ticks within 24 hours, offering up to 30 days of protection.

Ideal for Large Dogs
Perfect for dogs weighing between 45-88 pounds, ensuring effective flea and tick prevention.

Affordable and Effective
Praised for its cost-effectiveness compared to similar brands like Frontline and Advantix.
8.8

Very Good

Our Rating

9.9
Precision

8.0
Simple to use

8.0
Aroma
9

Trifexis

Trifexis Heartworm Prevention | Treats & Controls Flea Infestations + 4 Other Worms | Dogs 40.1-60 lbs.|1 Chewable
8.7

Very Good

Our Rating
10

YUMA'S
Flea and Tick Prevention for Dogs Chewables - 170 Treats - Natural Dog Flea and Tick Treatment Chewable Supplement - Oral Pills - All Breeds & Ages - Soft Chews - Made in USA - Chicken Flavor
Main highlights

Natural Flea Prevention
Defend your dogs from pests naturally, ensuring itch-free protection without harmful chemicals.

Ideal for All Breeds
Perfect for teacup pups to gentle giants, effective across all breeds and ages.

Customer Praised Taste
Highly praised for its chicken flavor, making daily administration hassle-free.
Key specs
- Application Method:Chewable tablets
- Protection Type:Flea & tick prevention
- Active Ingredients:N/A
- Treatment Duration:Daily
- Flavor:Chicken
8.6

Very Good

Our Rating

9.1
Simple to use

8.0
Flavor

8.0
worth the money