10 Best arthritis relief sprays of 2025

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Best Choice

1

Medline
Medline ActivICE Spray Cooling Gel, Topical Pain Relief for Arthritis, Joint, Muscle, Back & Body Aches & Pain, 4 oz (3 Count)
Main highlights

Cooling and Long-Lasting Relief
Provides quick, cooling relief with 8% menthol in a non-greasy, water-based spray.

Perfect for Active Lifestyles
Ideal for backaches, sore muscles, and stiff joints, especially before or after workouts.

Rapid Absorption Praised
Customers appreciate its fast absorption and immediate soothing sensation.
9.6

Exceptional

Our Rating
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Value for Money

2

Biofreeze
Biofreeze Professional Strength Pain Relief Aerosol Spray, Arthritis Pain Reliever, Knee & Lower Back Pain Relief, Sore Muscle Relief, FSA Eligible, 2 Pack (4 FL OZ Biofreeze Menthol Spray)

15% Off
Main highlights

Key Features
Fast-acting, cooling menthol relief for minor aches, with upside-down spray technology. Clinician recommended, animal-friendly, NSAID-free.

Ideal Use Cases
Perfect for backache, arthritis, strains, bruises, sprains, and hard-to-reach areas like the middle back, neck, and lower extremities.

Customer Praise
Users highly value its quick pain relief and the convenience of the 360 spray bottle, especially for reaching difficult areas.
9.5

Excellent

Our Rating

9.1
pain management

8.7
worth the money

8.4
Long life
3

TIDL
TIDL Cryotherapy Pain Relief Spray, 3 Oz, Targeted Neck Pain, Joint & Muscle Pain Relief, Organic, Plant-Based Menthol, Instant Cooling for Arthritis, Back & Knee Pain
Main highlights

Fast-Acting and Potent Pain Relief
Our Plant-Powered Cryotherapy Spray offers rapid relief for muscle and joint pain using all-natural, plant-based ingredients.

Ideal for Post-Workout Recovery
Perfect for athletes and those with active lifestyles, providing comprehensive relief from inflammation, back pain, arthritis, and muscle soreness.

Easy and Effective Application
Customers appreciate the 360-Degree Spray Technology for even coverage and the cooling effect without stickiness, despite some complaints about the strong smell.
9.4

Excellent

Our Rating

9.3
pain management

8.9
Simple to use

8.0
Aroma
4

Icy Hot

Icy Hot Original Pain Relief Dry Spray with 16% Menthol, Pain Relief for Muscles & Joints, 4 oz.
9.3

Excellent

Our Rating
5

Aleve
AleveX Pain Relieving Spray, Fast Acting & Fast Drying for Targeted Pain Relief, 3.2 oz Spray
Main highlights

Powerful Topical Pain Relief
Made with Camphor and maximum strength Menthol 16, providing fast-acting, long-lasting relief for minor muscle and joint aches.

Ideal for Active Lifestyles
Perfect for those experiencing arthritis, backaches, strains, sprains, and bruises, especially beneficial for physically active individuals.

Fast Acting and Effective
Customers consistently praise the product's immediate pain relief and ease of use, highlighting its effectiveness and convenience.
9.1

Excellent

Our Rating

9.3
pain management

8.9
Simple to use

8.4
Long life
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6

Icy Hot

Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces
8.9

Very Good

Our Rating
7

Biofreeze
Biofreeze Menthol Spray 3 FL OZ Colorless Aerosol Spray Associated with Sore Muscles, Arthritis, Simple Backaches, and Joint Pain (Packaging May Vary) (1)
Main highlights

Key Features and Benefits
Clinician-recommended, fast-acting menthol formula with 360 spray technology for hard-to-reach areas; FSA/HSA eligible and not tested on animals.

Ideal Use Cases
Perfect for relieving minor aches and pains of muscles and joints associated with backache, strains, bruises, and sprains.

Customer Reviews Highlight
Most praised for its quick pain relief and ease of use, especially the continuous flow spray design for reaching difficult areas.
8.8

Very Good

Our Rating

8.9
pain management

8.0
Simple to use

8.0
Long life
8

Stopain
Stopain Pain Relief Spray 4oz, USA Made, Max Strength Fast Acting with Menthol, MSM, Glucosamine for Lower Back, Arthritis, Knee, Neck, Joints, HSA FSA Approved OTC Topical Analgesic Product
Main highlights

Immediate Penetrating Relief
Stopain spray offers fast-acting relief from joint, muscle, and arthritis pain with a non-greasy, non-irritating formula free from dyes, fragrances, and preservatives.

Ideal for Hard-to-Reach Areas
Perfect for back, knees, shoulders, and other hard-to-reach areas, this spray provides easy application without the need for patches or ointments.

Highly Effective for Quick Pain Relief
Customers frequently praise the product for its instant pain relief, especially for conditions like knee pain, neuropathy, and joint stiffness.
8.7

Very Good

Our Rating

9.7
pain management

9.3
Simple to use

8.0
Aroma
9

Aspercreme
Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.
Main highlights

Key Features
Max Strength Lidocaine for muscle, joint, and back pain relief. Odor-free, fast-acting, and dries quickly. Non-greasy and works at any angle.

Ideal Use Cases
Perfect for athletes, seniors, or anyone seeking quick pain relief in muscles and joints without the mess or smell.

Customer Reviews
Most praised for its quick pain relief and convenience. Users love the odor-free formula and how it doesn`t leave hands or skin greasy.
8.6

Very Good

Our Rating

9.1
Simple to use

8.0
worth the money

8.0
pain management
10

Dr. Hess

Dr. Hess Spray, Extra Strength Natural Joint & Muscle Relief for Sports Injuries, Arthritis, Swelling & Aching, with Aloe, Arnica, Tea Tree Oil & Camphor, Travel Size, 3.4 Oz (96g)
8.5

Good

Our Rating

10 Best arthritis relief sprays of 2025

1

Medline ActivICE Spray Cooling Gel, Topical Pain Relief for Arthritis, Joint, Muscle, Back & Body Aches & Pain, 4 oz (3 Count)

How do we rank?

How do we rank?

Analyzing top stores

2

Biofreeze Professional Strength Pain Relief Aerosol Spray, Arthritis Pain Reliever, Knee & Lower Back Pain Relief, Sore Muscle Relief, FSA Eligible, 2 Pack (4 FL OZ Biofreeze Menthol Spray)

9.1

8.7

8.4

3

TIDL Cryotherapy Pain Relief Spray, 3 Oz, Targeted Neck Pain, Joint & Muscle Pain Relief, Organic, Plant-Based Menthol, Instant Cooling for Arthritis, Back & Knee Pain

9.3

8.9

8.0

4

Icy Hot Original Pain Relief Dry Spray with 16% Menthol, Pain Relief for Muscles & Joints, 4 oz.

5

AleveX Pain Relieving Spray, Fast Acting & Fast Drying for Targeted Pain Relief, 3.2 oz Spray

9.3

8.9

8.4

6

Icy Hot Max Strength Pain Relief Spray with Lidocaine Plus Menthol, 4 Ounces

7

Biofreeze Menthol Spray 3 FL OZ Colorless Aerosol Spray Associated with Sore Muscles, Arthritis, Simple Backaches, and Joint Pain (Packaging May Vary) (1)

8.9

8.0

8.0

8

Stopain Pain Relief Spray 4oz, USA Made, Max Strength Fast Acting with Menthol, MSM, Glucosamine for Lower Back, Arthritis, Knee, Neck, Joints, HSA FSA Approved OTC Topical Analgesic Product

9.7

9.3

8.0

9

Aspercreme Lidocaine Dry Spray Soothes Aggravated Nerves, Numbing Topical Pain Relief Spray with Max-Strength 4% Lidocaine Sprays at Any Angle, 4 Oz.

9.1

8.0

8.0

10

Dr. Hess Spray, Extra Strength Natural Joint & Muscle Relief for Sports Injuries, Arthritis, Swelling & Aching, with Aloe, Arnica, Tea Tree Oil & Camphor, Travel Size, 3.4 Oz (96g)

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