10 Best antihistamine non drowsies of 2025

Save up to 32% off

Best Choice

1

Claritin
Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets
Main highlights

24-Hour Non-Drowsy Relief
Provides powerful, all-day allergy relief without causing drowsiness.

Ideal for Seasonal Allergies
Perfect for managing symptoms from pollen, dust, and pet allergens.

Highly Recommended for Spring
Praised for effectiveness during peak allergy seasons like Spring.
Key specs
- form:Tablet
- active ingredient:10 milligrams loratadine
- symptom relief:Allergy symptoms
- dosage:N/A
- pack size:100 days
9.9

Exceptional

Our Rating

9.7
simple to consume

8.9
worth the money
How do we rank?

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Real users impact

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Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Claritin
Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 30 Tablets + 1ct On-The-Go Relief
Main highlights

Powerful 24-Hour Relief
Provides non-drowsy relief for indoor and outdoor allergies.

Ideal for Travelers
Includes 31 tablets, with one conveniently packaged for travel.

Praised for Small Size
Customers appreciate the compact bottle for easy storage and travel.
Key specs
- form:Tablet
- active ingredient:Loratadine 10mg
- symptom relief:Sneezing, runny nose, itchy eyes
- dosage:10mg per tablet
- pack size:31 days
9.7

Exceptional

Our Rating
3

Curist

Curist Loratadine 10mg 365 Count - All Day Non Drowsy Allergy Medicine - 24 Hour Antihistamine Tablets for Runny Nose, Itchy Eyes, & Sneezing - Indoor & Outdoor Allergy Medicine for Adults

10% Off
9.6

Exceptional

Our Rating
4

Allegra
Allegra Hives Antihistamine 24-Hour Tablets, Non-Drowsy Hive Reduction and Hive Itch Relief, 180 mg Fexofenadine HCI, 30-Count

13% Off
Main highlights

24-Hour Non-Drowsy Relief
Offers 24-hour relief from hives and itching without causing drowsiness.

Ideal for Chronic Hives
Perfect for individuals with persistent hives seeking effective relief.

Highly Effective for Hives
Praised by users for being the only effective solution for hives.
Key specs
- form:Tablets
- active ingredient:fexofenadine HCI
- symptom relief:Hives and itching
- dosage:One tablet daily
- pack size:30-count
9.4

Excellent

Our Rating

9.7
quality of ingredients

9.3
pain management

8.0
worth the money
5

HealthA2Z
HealthA2Z® Allergy Relief | Loratadine 10mg | Antihistamine | Relief from Itchy Throat, Sneezing, Runny Noses | 24-Hours Allergy Medicine (300 Tablets)

32% Off
Main highlights

24-Hour Non-Drowsy Relief
Provides effective, non-drowsy allergy relief for 24 hours.

Ideal for Daily Allergy Management
Perfect for managing symptoms from pollen, dust, and pets.

Value for Money
Praised for its affordability and quantity compared to brands.
9.1

Excellent

Our Rating
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6

Amazon Basic Care
Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, Antihistamine, 10 mg, 365 Count (Packaging may vary)
Main highlights

24-Hour Relief
Provides up to 24 hours of temporary relief from allergy symptoms.

Indoor and Outdoor Use
Effective for both indoor and outdoor allergy symptom relief.

Budget-Friendly Alternative
Praised for being a cost-effective alternative to Zyrtec and Allertec.
Key specs
- form:tablets
- active ingredient:cetirizine hydrochloride
- symptom relief:allergy symptoms
- dosage:10 mg
- pack size:N/A
9.0

Excellent

Our Rating
7

Allegra

Allegra Adult 12-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 60 mg Fexofenadine HCI Antihistamine Pill, 24-Count

19% Off
8.8

Very Good

Our Rating
8

ValuMeds
ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))
Main highlights

24-Hour Allergy Relief
Experience effective, long-lasting relief from allergies with cetirizine hydrochloride.

Ideal for Busy Lifestyles
Non-drowsy formula perfect for work, school, or daily activities.

Highly Rated Value
Customers appreciate the quality and cost-effectiveness compared to brand names.
8.6

Very Good

Our Rating

9.9
simple to consume

9.3
worth the money

9.3
quality of ingredients
9

GenCare
GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

23% Off
Main highlights

24 Hour Non Drowsy Relief
Provides full-day relief from allergies without causing drowsiness.

Effective for Indoor and Outdoor Allergies
Ideal for hay fever, pollen, dust, pet dander, and seasonal allergies.

Comparable to Brand Name Effectiveness
Praised for being as effective as brand-name allergy medications.
Key specs
- form:Tablets
- active ingredient:Cetirizine HCL
- symptom relief:Allergy, itching, congestion
- dosage:10mg
- pack size:200 pills
8.5

Good

Our Rating

9.7
simple to consume

9.5
worth the money
10

Amazon Basic Care

Amazon Basic Care All Day Allergy Relief, Fexofenadine Hydrochloride Tablets, 180 mg, Antihistamine, Non-Drowsy, 24-Hour Relief, 30 Count
8.4

Good

Our Rating

10 Best antihistamine non drowsies of 2025

1

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 100 Tablets

9.7

8.9

How do we rank?

How do we rank?

Analyzing top stores

2

Claritin Allergy Medicine for Adults, 24-Hour Non-Drowsy Loratadine 10mg Pills, Antihistamine, 30 Tablets + 1ct On-The-Go Relief

3

Curist Loratadine 10mg 365 Count - All Day Non Drowsy Allergy Medicine - 24 Hour Antihistamine Tablets for Runny Nose, Itchy Eyes, & Sneezing - Indoor & Outdoor Allergy Medicine for Adults

4

Allegra Hives Antihistamine 24-Hour Tablets, Non-Drowsy Hive Reduction and Hive Itch Relief, 180 mg Fexofenadine HCI, 30-Count

9.7

9.3

8.0

5

HealthA2Z® Allergy Relief | Loratadine 10mg | Antihistamine | Relief from Itchy Throat, Sneezing, Runny Noses | 24-Hours Allergy Medicine (300 Tablets)

6

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, Antihistamine, 10 mg, 365 Count (Packaging may vary)

7

Allegra Adult 12-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 60 mg Fexofenadine HCI Antihistamine Pill, 24-Count

8

ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))

9.9

9.3

9.3

9

GenCare - Cetirizine HCL 10 mg (200 Caplets) - 24 Hour Allergy Relief Pills - Non Drowsy Generic OTC Allergy Medication - Antihistamine Medicine for Sneezing, Runny Nose & Itchy Eyes - Generic Zyrtec

9.7

9.5

10

Amazon Basic Care All Day Allergy Relief, Fexofenadine Hydrochloride Tablets, 180 mg, Antihistamine, Non-Drowsy, 24-Hour Relief, 30 Count

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