10 Best allergy medicine for adults of 2025

Save up to 29% off

Best Choice

1

Allegra
Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 180 mg Fexofenadine HCI Antihistamine Pill, 100-Count

20% Off
Main highlights

24-Hour Relief
One tablet provides round-the-clock relief from allergy symptoms.

Versatile Allergy Use
Effective for indoor, outdoor, seasonal, and pet allergies.

Convenience and Availability
Praised for being easy to carry and readily available.
Key specs
- dosage:24-hour
- form:tablet
- active ingredient:fexofenadine HCI
- usage instructions:One tablet daily
- symptom relief:sneezing, runny nose, itchy eyes
9.8

Exceptional

Our Rating
How do we rank?

Powerful technology We scan thousands of products and stores, analyzing reviews to find what matters most to users like you

Careful review Our team ensures quality, value, and fit based on real user feedback

Trusted insights AI and human analysis guide your decisions, reflecting real user priorities
Real users impact

Thousands of users trust our site daily

Based on millions of stores and reviews

Shoppers influence our rankings
Analyzing top stores
Value for Money

2

Amazon Basic Care
Amazon Basic Care All Day Allergy Relief, Fexofenadine Hydrochloride Tablets, 180 mg, Antihistamine, Non-Drowsy, 24-Hour Relief, 150 Count
Main highlights

24-Hour Non-Drowsy Relief
Contains fexofenadine hydrochloride 180 mg for all-day allergy relief.

Ideal for All Allergy Types
Effective against indoor and outdoor allergy symptoms for ages 12+.

Cost-Effective Alternative
Praised for affordability and comparable effectiveness to Allegra.
Key specs
- dosage:One dose
- form:tablets
- active ingredient:fexofenadine hydrochloride 180 mg
- usage instructions:adults and children 12+
- symptom relief:itchy, watery eyes, runny nose
9.7

Exceptional

Our Rating
3

Amazon Basic Care
Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 90 Count (Packaging may vary)
Main highlights

24-Hour Allergy Relief
Provides relief from indoor and outdoor allergy symptoms for 24 hours.

Effective for Dermatographism
Ideal for reducing itchiness and hives associated with skin allergies.

Budget-Friendly Alternative
Praised by customers for being a cost-effective substitute for Zyrtec.
9.6

Exceptional

Our Rating
4

MAJOR
Major Allergy Loratadine 10 mg Tablets - Non-Drowsy Allergy Medicine for Adults and Kids Ages 6+ - Promotes 24-Hour Allergy Relief - Daily Allergy Tablets - Antihistamine - 300 Tablets
Main highlights

Large Quantity and Cost Efficiency
300 tablets provide a long-lasting supply, reducing frequent purchases and offering great value for money.

Ideal for Daily Allergy Relief
Perfect for individuals needing consistent allergy management without frequent re-purchasing.

Highly Praised for Affordability
Customers appreciate the significant cost savings compared to national brands.
9.5

Excellent

Our Rating
5

ValuMeds
ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))
Main highlights

24-Hour Allergy Relief
Experience effective, long-lasting relief from allergies with cetirizine hydrochloride.

Ideal for Busy Lifestyles
Non-drowsy formula perfect for work, school, or daily activities.

Highly Rated Value
Customers appreciate the quality and cost-effectiveness compared to brand names.
9.3

Excellent

Our Rating

9.9
simple to consume

9.3
worth the money

9.3
quality of ingredients
See Today’s Deals & Prices
6

Xyzal
Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 80 Count

27% Off
Main highlights

24-Hour Allergy Relief
Xyzal provides effective 24-hour relief from allergy symptoms.

Ideal for Nighttime Use
Best taken at night to prevent morning allergy symptoms.

Highly Effective for Most Allergies
Praised for clearing allergies, especially in winter and spring.
9.2

Excellent

Our Rating

9.9
simple to consume

9.3
Flavor

9.3
worth the money
7

HealthA2Z

HealthA2Z® Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses (300 Count (Pack of 1))

15% Off
8.9

Very Good

Our Rating
8

Benadryl
Benadryl Ultratabs Allergy Relief Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Relief of Cold & Allergy Symptoms Like Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct

29% Off
Main highlights

Powerful Allergy Relief
Benadryl Ultratabs provide fast relief from sneezing, runny nose, itchy eyes, and throat.

Ideal for Seasonal Allergies
Perfect for managing symptoms from pollen, dust, mold, and pet dander.

Highly Effective
Customers praise its effectiveness in relieving allergy symptoms quickly.
8.6

Very Good

Our Rating

9.7
simple to consume

9.5
worth the money
9

Amazon Basic Care
Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count
Main highlights

Powerful Allergy Relief
Contains diphenhydramine HCl 25 mg for effective multi-symptom relief.

Nighttime Use
Ideal for nighttime use to relieve allergies and aid sleep.

Highly Praised Sleep Aid
Customers appreciate its effectiveness as a sleep aid.
8.5

Good

Our Rating

9.9
simple to consume

9.7
worth the money

9.3
Flavor
10

Zyrtec
Zyrtec 24 Hour Allergy Relief Liquid Gels, Antihistamine Capsules with Cetirizine HCl Allergy Medicine for All-Day Relief from Runny Nose, Sneezing, Itchy Eyes & More, 40 Count

18% Off
Main highlights

24-Hour Relief with Cetirizine Hydrochloride
Provides all-day relief from runny nose, sneezing, and itchy eyes.

Ideal for Indoor and Outdoor Allergies
Treats allergies caused by dust, mold, pet dander, pollen, and grasses.

Fast-Acting and Non-Drowsy Formula
Praised for being reliable and not causing drowsiness.
8.2

Good

Our Rating

9.9
simple to consume

9.1
worth the money

10 Best allergy medicine for adults of 2025

1

Allegra Adult 24-Hour Allergy Relief Tablets, Non-Drowsy Indoor and Outdoor Allergy Medicine, 180 mg Fexofenadine HCI Antihistamine Pill, 100-Count

How do we rank?

How do we rank?

Analyzing top stores

2

Amazon Basic Care All Day Allergy Relief, Fexofenadine Hydrochloride Tablets, 180 mg, Antihistamine, Non-Drowsy, 24-Hour Relief, 150 Count

3

Amazon Basic Care All Day Allergy, Cetirizine Hydrochloride Tablets, 10 mg, Antihistamine, 90 Count (Packaging may vary)

4

Major Allergy Loratadine 10 mg Tablets - Non-Drowsy Allergy Medicine for Adults and Kids Ages 6+ - Promotes 24-Hour Allergy Relief - Daily Allergy Tablets - Antihistamine - 300 Tablets

5

ValuMeds 24-Hour Allergy Medicine Antihistamine for Pollen, Hay Fever, Dry, Itchy Eyes, Allergies | Cetirizine HCl 10mg Caplets, Compare to Leading Brand (300 Count (Pack of 1))

9.9

9.3

9.3

6

Xyzal 24 Hour Allergy Relief Medicine, Original Prescription Strength Antihistamine, Levocetirizine Dihydrochloride Tablets, 5 mg, 80 Count

9.9

9.3

9.3

7

HealthA2Z® Allergy Relief | Cetirizine 10mg | All Day Allergy Relief | Indoor & Outdoor | Relief from Itchy Throat, Sneezing, Runny Noses (300 Count (Pack of 1))

8

Benadryl Ultratabs Allergy Relief Medicine, 25 mg Diphenhydramine HCl Antihistamine Tablets For Relief of Cold & Allergy Symptoms Like Sneezing, Runny Nose, & Itchy Eyes & Throat, 100 ct

9.7

9.5

9

Amazon Basic Care Complete Allergy Relief, Diphenhydramine HCl 25 mg, Relieves Symptoms, Antihistamine Tablets, 400 Count

9.9

9.7

9.3

10

Zyrtec 24 Hour Allergy Relief Liquid Gels, Antihistamine Capsules with Cetirizine HCl Allergy Medicine for All-Day Relief from Runny Nose, Sneezing, Itchy Eyes & More, 40 Count

9.9

9.1

Sign up and get exclusive special deals